Abstract: A process for the preparation of optically pure (-)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid by reaction of L-phenylalanine with formaldehyde in aqueous solution or paraformaldehyde in the presence of hydroiodic acid is described.
Abstract: An expedient synthesis of 4-(6-methoxynaphth-2-yl)-2-butanone is carried out by reacting 2-bromo-6-methoxynaphthalene with 3-ethylenedioxybutene in the presence of PdCl.sub.2 and triphenylphosphine, hydrogenating the 6-methoxy-2-(3-ethylene-dioxybuten-1-yl)naphthalene obtained and then hydrolysing the latter with an acid.
Abstract: A process for the preparation of rufloxacin, a compound of the formula I ##STR1## and salts thereof is described. This is effected by reducing a quinoline disulfide of formula (II) as herein defined, and subjecting the resulting 2-mercaptoethyl quinoline of formula (III) as herein defined to a cyclization in a basic medium and hydrolyzing the rufloxacin ester thus obtained and, if desired, forming the salts thereof.
Abstract: A process for preparing rufloxacin using a compound of the formula I ##STR1## as a starting material is described, where R is herein defined.
Abstract: Propofol is purified by reaction of the raw 2,6-diisopropylphenol with an alkaline agent, by isolation of the alkaline metal salt and by neutralization thereof. There is thus obtained a propofol having a purity of at least 99.90%.
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