Patents Assigned to Arena Phamaceuticals, Inc.
  • Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates related thereto
    Patent number: 8802845
    Abstract: The present invention provides processes, methods and intermediates for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, salts, hydrates and crystal forms thereof which are useful as serotonin (5-HT) receptor agonists for the treatment of, for example, central nervous system disorders such as obesity.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 12, 2014
    Assignee: Arena Phamaceuticals, Inc.
    Inventors: Ulrich Weigl, Frank Porstmann, Christoph Straessler, Lars Ulmer, Ulf Koetz
  • Constitutively activated human G protein coupled receptors
    Patent number: 8440391
    Abstract: The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown (“orphan GPCR receptors”), and most particularly to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: May 14, 2013
    Assignee: Arena Phamaceuticals, Inc.
    Inventors: Ruoping Chen, Chen W. Liaw, Kevin P. Lowitz, Derek T. Chalmers, Dominic P. Behan
  • Crystalline Forms Of (R)-8-Chloro-1-Methyl-2,3,4,5-Tetrahydro-1H-3-Benzazepine Hydrochloride
    Publication number: 20100004223
    Abstract: The present invention is directed to crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, compositions containing the same, preparations, and uses thereof.
    Type: Application
    Filed: December 20, 2005
    Publication date: January 7, 2010
    Applicant: Arena Phamaceuticals, Inc.
    Inventors: Rajesh K. Agarwal, William l. Betts, James A. Henshilwood, Yuan-Hon Kiang, Noah Post