Abstract: Forming a ferrite thin film laminate includes heating a layered assembly to form a laminate. The layered assembly includes a first coated substrate having a first ferrite layer opposite a first thermoplastic surface and a second coated substrate having a second ferrite layer opposite a second thermoplastic surface to form a laminate. Each coated substrate is formed by forming a ferrite layer on a surface of a thermoplastic substrate. The coated substrates are arranged such that the first ferrite layer contacts the second thermoplastic surface. Heating the layered assembly includes bonding the first coated substrate to the second coated substrate such that the first ferrite layer is sandwiched between a first thermoplastic substrate and a second thermoplastic substrate. The ferrite thin film laminate may include a multiplicity of coated substrates.
Type:
Grant
Filed:
October 26, 2012
Date of Patent:
April 18, 2017
Assignee:
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: The present invention relates to therapeutic agents comprising bispecific recombinant antibody fragments to selectively clear a protein associated with a neurological disease and methods of use of these therapeutic agents to treat neurological diseases.
Type:
Application
Filed:
October 24, 2016
Publication date:
April 13, 2017
Applicant:
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF
Abstract: A transition metal hydroxy-anion electrode material for lithium-ion battery cathodes includes the charge-neutral structure Mx(OH)n(XO4)m, where M is one or more transition metals, x is the total number of transition metal atoms, X is sulfur or phosphorus, and x, n, and m are integers. (OH)n(XO4)m is a hydroxysulfate or hydroxyphosphate, and M can be one or more (e.g., a solid solution of) transition metals selected from the group consisting of copper, iron, manganese, nickel, vanadium, cobalt, zinc, chromium, and molybdenum. A lithium-ion battery may have a cathode including Mx(OH)n(XO4)m as a cathode material, and an electronic device may include a lithium-ion battery having a cathode including Mx(OH)n(XO4)m as a cathode material.
Type:
Grant
Filed:
June 20, 2013
Date of Patent:
March 7, 2017
Assignee:
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: Some embodiments include a method. The method can comprise: providing a carrier substrate; providing an adhesion modification layer over the carrier substrate; providing a device substrate; and coupling the device substrate and the carrier substrate together, the adhesion modification layer being located between the device substrate and the carrier substrate when the device substrate and the carrier substrate are coupled together. In these embodiments, the adhesion modification layer can be configured so that the device substrate couples indirectly with the carrier substrate by way of the adhesion modification layer with a first bonding force that is greater than a second bonding force by which the device substrate couples with the carrier substrate absent the adhesion modification layer. Other embodiments of related methods and devices are also disclosed.
Type:
Application
Filed:
November 11, 2016
Publication date:
March 2, 2017
Applicant:
Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of Ariz
Inventors:
Emmett Howard, Nicholas Munizza, Paul Yee, Michael Marrs
Abstract: The invention provides compounds of formulae (I), (II), (III), and (IV): and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers and Alzheimer's disease.
Type:
Grant
Filed:
September 13, 2012
Date of Patent:
February 21, 2017
Assignee:
Arizona Board of Regents, A Body Corporate of the State of Arizona Acting for and on behalf of Arizona State University
Inventors:
Carl E. Wagner, Peter W. Jurutka, Pamela A. Marshall
Abstract: Some embodiments include an imaging system. The image sensor array includes multiple image sensor sheets configured in an array grid. Each image sensor sheet of the multiple image sensor sheets can include a flexible substrate layer, and the flexible substrate layer can include a first flexible substrate side and a second flexible substrate side opposite the first flexible substrate side. Meanwhile, each image sensor sheet of the multiple sensor sheets can include multiple image sensors over the first flexible substrate side, the multiple image sensors can include multiple flat panel image detectors configured in a sheet grid, and the image sensor array can include an approximately constant pixel pitch. Other embodiments of related systems and methods are also disclosed.
Type:
Grant
Filed:
December 12, 2014
Date of Patent:
February 14, 2017
Assignee:
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: The present invention provides methods for tumor treatment by administering an inhibitor of quiescin sulfhydryl oxidase 1 (QSOX1), compositions comprising such inhibitors, and methods for identifying such inhibitors.
Type:
Grant
Filed:
November 6, 2015
Date of Patent:
January 17, 2017
Assignee:
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: A method and related microfluidic chip and kit for high throughput detection of proteins of interest contained in a sample is disclosed. The method comprises of specifically labeling fusion proteins in a complex sample with fusion tag specific fluorophores that specifically bind the fusion tags coupled to the proteins of interest, and subjecting the sample to automated capillary electrophoresis, wherein the presence of the proteins of interest in the sample is detected by fluorescence signals associated with the fusion tag specific fluorophores.
Type:
Grant
Filed:
November 6, 2013
Date of Patent:
January 3, 2017
Assignee:
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
Inventors:
Justin Saul, Ji Qiu, Joshua LaBaer, Mitch Magee, John Chaput, Sujay Sau
Abstract: The present invention relates to therapeutic agents comprising bispecific recombinant antibody fragments to selectively clear a protein associated with a neurological disease and methods of use of these therapeutic agents to treat neurological diseases.
Type:
Grant
Filed:
January 10, 2013
Date of Patent:
December 6, 2016
Assignee:
Arizona Board of Regents, a Body Corporate of the State of Arizona, Acting for and on Behalf of Arizona State University
Abstract: Systems, methods, and media for optical recognition are provided. In some embodiments, systems for optical recognition are provided, the systems comprising: at least one hardware processor that: identifies a plurality of fixation points in optically detected data; identifies features of the plurality of fixation points; and identifies one or more characteristics of an object represented in the optically detected data. In some embodiments, methods for optical recognition are provided, the methods comprising: identifying a plurality of fixation points in optically detected data using a hardware processor; identifying features of the plurality of fixation points using the hardware processor; and identifying one or more characteristics of an object represented in the optically detected data using the hardware processor.
Type:
Grant
Filed:
July 1, 2013
Date of Patent:
November 22, 2016
Assignee:
Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University
Abstract: Some embodiments include a method. The method can include providing a carrier substrate, providing a release layer over the carrier substrate, and providing a device substrate over the carrier substrate and the release layer. Providing the device substrate can include bonding the device substrate to the carrier substrate, and bonding the device substrate to the release layer. Further, providing the release layer can include bonding the release layer to the carrier substrate. Meanwhile, the release layer can include polymethylmethacrylate, and the device substrate can be bonded to the carrier substrate with a first adhesion strength, the device substrate can be bonded to the release layer with a second adhesion strength less than the first adhesion strength, and the release layer can be bonded to the carrier substrate with a third adhesion strength greater than the second adhesion strength. Other embodiments of related methods and devices are also disclosed.
Type:
Application
Filed:
July 22, 2016
Publication date:
November 10, 2016
Applicant:
Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Ariz
Inventors:
Emmett Howard, Nicholas Munizza, Paul Yee
Abstract: The invention provides methods for identifying cell binding and/or lytic polypeptides that permit production of specific polypeptide therapeutics in a high throughput manner.
Type:
Grant
Filed:
November 1, 2012
Date of Patent:
November 1, 2016
Assignee:
Arizona Board of Regents, a Body Corporate of the State of Arizona, Acting for and on Behalf of Arizona State University
Inventors:
Valeriy Domenyuk, Chris Diehnelt, Stephen Johnston
Abstract: Methods, systems, and media for generating and/or analyzing medical images having elongated structures are provided. In some embodiments, a method for analyzing medical images is provided, the method comprising: receiving a plurality of images, wherein each of the plurality of images includes a portion of an elongated structure; receiving a location of interest within a least one of the plurality of images; determining an orientation of the elongated structure in response to receiving the location of interest; adjusting image planes of each of the plurality of images to correspond with the orientation of the elongated structure; and causing the elongated structure to be displayed in the adjusted image planes.
Type:
Grant
Filed:
September 10, 2013
Date of Patent:
September 20, 2016
Assignee:
Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University
Abstract: Some embodiments include a semiconductor device. The semiconductor device includes a transistor having a gate metal layer, a transistor composite active layer, and one or more contact elements over the transistor composite active layer. The transistor composite active layer includes a first active layer and a second active layer, the first active layer is over the gate metal layer, and the second active layer is over the first active layer. Meanwhile, the semiconductor device also includes one or more semiconductor elements forming a diode over the transistor. The semiconductor element(s) have an N-type layer over the transistor, an I layer over the N-type layer, and a P-type layer over the I layer. Other embodiments of related systems and methods are also disclosed.
Type:
Application
Filed:
March 9, 2015
Publication date:
September 8, 2016
Applicant:
Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Ariz
Abstract: Some embodiments include an imaging system. The imaging system includes an active matrix pixel array having a flexible substrate and a pixel. The pixel includes a transistor over the flexible substrate, and the transistor includes multiple active layers having a first active layer and a second active layer over the first active layer. Further, the active matrix pixel array also includes a photodiode over the transistor, and the photodiode includes an N-type layer over the transistor, an I layer over the N-type layer, and a P-type layer over the I layer. Meanwhile, the imaging system also includes a flexible scintillator layer over the active matrix pixel array. Other embodiments of related systems and methods are also disclosed.
Type:
Application
Filed:
March 9, 2015
Publication date:
September 8, 2016
Applicant:
Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Ariz
Abstract: Substrates may be bonded according to a method comprising contacting a first bonding surface of a first substrate with a second bonding surface of a second substrate to form an assembly, and compressing the assembly in the presence of an oxidizing atmosphere under suitable conditions to form a bonding layer between the first and second surfaces, wherein the first bonding surface comprises a polarized surface layer; the second bonding surface comprises a hydrophilic surface layer; the first and second bonding surfaces are different.
Type:
Grant
Filed:
September 25, 2013
Date of Patent:
August 16, 2016
Assignee:
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
Inventors:
Nichole Herbots, Ross Bennett-Kennett, Ashlee Murphy, Brett Hughes, Ajjya Acharya, Clarizza Watson, Robert Culbertson
Abstract: The present disclosure provides methods for identifying therapeutic agents that are multifunctional radical quenchers. It also provides compounds of formula: and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.
Type:
Grant
Filed:
June 5, 2015
Date of Patent:
July 12, 2016
Assignee:
Arizona Board of Regents, a Body Corporate of the State of Arizona, Acting for and on Behalf of Arizona State University
Inventors:
Sidney Hecht, Omar Khdour, Sandipan Roy Chowdhury, Poulami Talukder