Patents Assigned to Arizona Board of Regents For and On Behalf of the University of Arizona
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Patent number: 10647810Abstract: Thermally reworkable epoxy resins prepared through a Diels-Alder reaction are described herein. A maleimide component is reacted with an electron donating component having a furan ring attached to an epoxy ether to produce the epoxy resins. The epoxy component generated by this method can be cured with different diamines lo form a robust network of epoxy material. The robust epoxy material is used as a reversible thermoset and as an adhesive. The robust epoxy network is heated at 90° C. temperature in a retro Diels-Alder fashion to produce colorless starting materials of the maleimide component and the furan component.Type: GrantFiled: August 9, 2016Date of Patent: May 12, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Douglas A. Loy, Peter McFadden, Robb E. Bagge
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Patent number: 10646695Abstract: Minimally invasive percutaneous methods, devices, and systems for placing guide wires in bones in a desired position and orientation and for facilitating the treatment of fractures such as but not limited to intertrochanteric fractures or other applications such as osteotomies. The methods, devices, and systems may allow for rapid and reproducible placement of a guide wire in a bone. Each degree of freedom may be controlled independently.Type: GrantFiled: July 7, 2016Date of Patent: May 12, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Daniel Latt, Ariana M. Nicolini, Mary Coffelt
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Publication number: 20200143906Abstract: The invention is directed to methods for selecting a treatment option for an activated B cell-like diffuse large B cell lymphoma (ABC DLBCL) subject, a germinal center B cell-like diffuse large B cell lymphoma (GCB DLBCL) subject, a primary mediastinal B cell lymphoma (PMBL) subject, a Burkitt lymphoma (BL) subject, or a mantle cell lymphoma (MCL) subject by analyzing digital gene expression data obtained from the subject, e.g., from a biopsy sample.Type: ApplicationFiled: January 17, 2020Publication date: May 7, 2020Applicants: The United States of America,as represented by the Secretary,Department of Health and Human Services, British Columbia Cancer Agency Branch, Arizona Board of Regents on Behalf of the University of Arizona, Universitat de Barcelona, Hospital Clinic de Barcelona, The Cleveland Clinic Foundation, Board of Regents of the University of Nebraska, Oregon Health & Science University, Julius-Maximilians-University of Würzburg, Oslo University Hospital HFInventors: Louis M. Staudt, George W. Wright, David William Scott, Joseph M. Connors, Randy D. Gascoyne, Lisa Rimsza, Elias Campo Guerri, Raymond Tubbs (Deceased), Timothy C. Greiner, James Robert Cook, Kai Fu, Paul Michael Williams, Chih-Jian Lih, Elaine S. Jaffe, Rita M. Braziel, Andreas Rosenwald, Erlend B. Smeland, Wing C. Chan, German Ott, Jan Delabie, Dennis Weisenburger
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Publication number: 20200138850Abstract: Disclosed herein is a method for promoting reduction of heat stress in animals, as well as a composition for use in the disclosed method. The composition comprises a glucan, silica, mineral clay, mannan, and optionally an endoglucanohydrolase, and may be administered to an animal that is susceptible to or suffers from heat stress.Type: ApplicationFiled: December 20, 2019Publication date: May 7, 2020Applicants: OmniGen Research, L.L.C., The Arizona Board of Regents on Behalf of the University of ArizonaInventors: James D. Chapman, David Calabotta, Neil E. Forsberg, Steven B. Puntenney, Robert Collier, Laun Hall
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Patent number: 10644801Abstract: A proactive and non-obtrusive channel probing scheme is provided to accurately predict channel power, gain, and optical signal to noise ratio (OSNR) without disrupting the existing connections. In one example, using a probe signal with 5 ?s pulse duration in a single-hop network, rapid wavelength switching is achieved with power excursions less than or equal to 0.2 dB for different loading configurations.Type: GrantFiled: June 29, 2017Date of Patent: May 5, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Daniel Kilper, Weiyang Mo, Houman Rastegarfar, Mariya A. Bhopalwala
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Patent number: 10645589Abstract: Systems and methods for adaptive method exploits self-interference suppression (SIS) and full-duplex (FD) capabilities in cognitive radio and dynamic spectrum access (DSA) systems to enable simultaneous transmission-and-sensing (TS) or transmission-and-reception (TR) over the same frequency channel in a single operation. The adaptive methods enable secondary users or units (SUs) to switch between different modes of operation, taking into account the primary units (PUs) state, the SUs' traffic, and standards' rules. These adaptive methods significantly enhance the SU throughput and reduce the probability of colliding with PU transmissions.Type: GrantFiled: October 30, 2017Date of Patent: May 5, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Marwan M. Krunz, Wessam Ahmed
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Publication number: 20200129124Abstract: A compliance monitor for wear on a head includes a data logger with processor, and memory containing firmware; with sensors that may include one or more of magnetometers, accelerometers, gyroscopes, and temperature sensors. The firmware is adapted to process sensor readings to determine intervals where the compliance monitor is attached to a person's head, and in embodiments is adapted to scan for signatures indicating donning of the compliance monitor. The method of determining wear of a head-mounted device by a person includes determining differences between a magnetic field measured at the start of a time interval and the time interval, differences between a temperature reading at a sensor on a head side of the head-mounted device and on an ambient side of the head-mounted device, accelerations of the head-mounted device indicative of wear, and rotations of the head-mounted device indicative of wear.Type: ApplicationFiled: July 21, 2017Publication date: April 30, 2020Applicant: Arizona Board of Regents on Behalf of the University of ArizonaInventors: Erin M. HARVEY, Joseph M. MILLER, Martha J. MOHLER, Janet M. ROVEDA
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Patent number: 10636955Abstract: Superconducting Meissner effect transistors, methods of modulating, and systems are disclosed. In one aspect a disclosed transistor includes a superconducting bridge between a first and a second current probe, the first and second current probe being electrically connected to a source and a drain electrical connection, respectively and a control line configured to emit a magnetic field signal having signal strength Hsig at the superconducting bridge. In one aspect the emitted magnetic field is configured to break Cooper pairs in the superconducting bridge.Type: GrantFiled: May 19, 2017Date of Patent: April 28, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventor: Christopher K. Walker
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Patent number: 10633517Abstract: Hydrotetrazine compounds having antioxidant properties and uses thereof are described herein. These compounds may be dihydrotetrazines, tetrahydrotetrazines, or hexahydrotetrazines that can be utilized as antioxidants for use in thermoplastics, thermosets and elastomers; free radical inhibitors to stabilize reactive chemicals, such as monomers against free radical polymerizations; and as anticorrosion agents in coatings to protect against metal oxidation. The hydrogenated tetrazines can donate hydrogen atom equivalents to terminate radical chain reactions. These compounds can change colors to signal when oxidation has occurred, and can be further recycled by reduction reactions.Type: GrantFiled: March 9, 2018Date of Patent: April 28, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Douglas A. Loy, Robb E. Bagge, Wenmo Sun
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Patent number: 10634743Abstract: The present invention provides a sample tube insertion guide that is adapted in reducing the possibility or the risk of breakage of a sample tube that is inserted into an orifice during insertion/removal of the sample tube through an orifice. In one particular embodiment, the sample tube insertion guide comprises: a plurality of rigid elongated guide elements (14), each of which comprises a top end (18T) and a bottom end (18B); and one or more slotted openings (38) between at least a pair of said rigid elongated guide elements (14), wherein said slotted openings (38) begin at the top end (18T) and extend continuously to at least 75% of the length of said rigid elongated guide elements (14).Type: GrantFiled: October 10, 2017Date of Patent: April 28, 2020Assignee: Arizona Board of Regents on behalf of the University of ArizonaInventors: Hamish S. Christie, Lee Macomber
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Patent number: 10633710Abstract: A method of identifying gene expression associated with recurrence free survival in a subject with cancer, comprising: a) assaying a sample from a subject diagnosed with cancer for the presence of altered gene expression of one or more genes selected from the group consisting of ADK, AP2B1, AVL9, CANX, DBT, DHRS7, DONSON, FAM190B, FGFR1, FOXN3, FZD5, GGH, GM2A, IGFBP5, ITSN2, LAMC1, LIFR, METTL7A, MT1F, MT1G, MT1P2, MT1X MT2A, NAB1, NCOA1, NCOR1, PAPOLA, PPME1, PPP1R13L, PRKAR2A, RABEP1, RBBP8, SGPL1, SIRT1, SNX2, SREK1, TAF1B, TMED5, and ZMIZ2; and b) identifying an outcome of decreased likelihood of recurrence free survival when altered gene expression relative to the level in a non-cancerous sample is present.Type: GrantFiled: August 14, 2015Date of Patent: April 28, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventor: Joe G. N. Garcia
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Patent number: 10617681Abstract: The present invention provides a compound of the formula: wherein ring Z is a 5-, 6- or 7-membered ring; R1 is C1-10 alkyl, C1-10 haloalkyl, optionally substituted aralkyl, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heteroaralkyl; R2 is C1-10 alkylene; and Y is optionally substituted aryl, optionally substituted heteroaryl, or a moiety of the formula —C(?O)—X1, wherein X1 is —OR3 or —NR4R5, where each of R3, R4 and R5 is H or C1-10 alkyl. The present invention also provides a method for using compound of Formula I to treat a wide variety of clinical conditions.Type: GrantFiled: December 31, 2018Date of Patent: April 14, 2020Assignee: Arizona Board of Regents on behalf of the University of ArizonaInventors: Ruben S. Vardanyan, Victor J. Hruby
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Patent number: 10619023Abstract: A method of making a solid composition by reacting a tetrazine component and a polymer component through an inverse electron demand Diels-Alder reaction (IEDDA). The solid composition formed by the Diels-Alder reaction is in the form of either a foam or a powder depending on the functional groups of the tetrazine component. The polymer component can be various substituted polybutadienes, mixtures of stereoisomeric polydienes, and polybutadiene copolymers. The gas produced during the reaction is nitrogen, hence, the solid composition can be considered a greener material than polyurethanes, which involves carbon monoxide release during the course of the reaction. The aromatized polymer can act as a built in anti-oxidant with up to two hydrogen atom equivalents per dihydropyridazine group. The polymers of dihydropyridazines are converted to polymeric pyridazine groups by aromatization and the aromatic polymer becomes more stable.Type: GrantFiled: August 9, 2016Date of Patent: April 14, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Douglas A. Loy, Robb E. Bagge
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Patent number: 10613328Abstract: Eye-tracked head-mounted displays are provide which, in one aspect, may utilize the same optics for eyetracking and image viewing, with a selected portion of the optics used for an eyetracking optical path and a selected portion of the display optics used for an image viewing optical path.Type: GrantFiled: March 1, 2017Date of Patent: April 7, 2020Assignees: THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, AUGMENTED VISION INCInventors: Hong Hua, Chunyu Gao
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Patent number: 10614966Abstract: Embodiments of the present disclosure are directed to carbon-containing composites which are suitable for use as electrodes in electrochemical systems. The composites are formed from a scaffold of graphene and carbon nanotubes. Graphene flakes form a plurality of generally planar sheets (e.g., extending in an x-y plane) separated in the direction of a composite axis (e.g., along a z-axis) and approximately parallel to one another. The carbon nanotubes extend between the graphene sheets and at least a portion of the carbon nanotubes are aligned in approximately the same direction, at a defined angle with respect to the composite axis. At least a portion of the scaffold is embedded within a porous carbon matrix (e.g., an activated carbon, a polymer derived graphitic carbon, etc.).Type: GrantFiled: August 11, 2015Date of Patent: April 7, 2020Assignee: Arizona Board of Regents on Behalf of the University of ArizonaInventors: Palash Gangopadhyay, Scott H. Tan
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Patent number: 10606080Abstract: Eye-tracked head-mounted displays are provide which, in one aspect, may utilize the same optics for eyetracking and image viewing, with a selected portion of the optics used for an eyetracking optical path and a selected portion of the display optics used for an image viewing optical path.Type: GrantFiled: December 21, 2017Date of Patent: March 31, 2020Assignees: THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, AUGMENTED VISION INC.Inventors: Hong Hua, Chunyu Gao
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Patent number: 10607717Abstract: The invention is directed to methods for selecting a treatment option for an activated B cell-like diffuse large B cell lymphoma (ABC DLBCL) subject, a germinal center B cell-like diffuse large B cell lymphoma (GCB DLBCL) subject, a primary mediastinal B cell lymphoma (PMBL) subject, a Burkitt lymphoma (BL) subject, or a mantle cell lymphoma (MCL) subject by analyzing digital gene expression data obtained from the subject, e.g., from a biopsy sample.Type: GrantFiled: November 5, 2014Date of Patent: March 31, 2020Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, British Columbia Cancer Agency Branch, Arizona Board of Regents on behalf of the University of Arizona, Universitat de Barcelona, Hospital Clinic de Barcelona, The Cleveland Clinic Foundation, Board of Regents of the University of Nebraska, Oregon Health and Science University, Julius-Maximilians-University of Würzburg, Oslo University Hospital HFInventors: Louis M. Staudt, George W. Wright, David William Scott, Joseph M. Connors, Randy D. Gascoyne, Lisa Rimsza, Elias Campo Guerri, Raymond Tubbs, Timothy C. Greiner, James Robert Cook, Kai Fu, Paul Michael Williams, Chih-Jian Lih, Elaine S. Jaffe, Rita M. Braziel, Andreas Rosenwald, Erlend B. Smeland, Wing C. Chan, German Ott, Jan Delabie, Dennis Weisenburger
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Patent number: 10604732Abstract: Disclosed herein are bioreactors that include a vessel with sides and a bottom, at least one opening in the vessel connected to a means for introducing a gas, and at least one scaffold in the vessel oriented substantially vertically in the vessel. The scaffolds are two substantially parallel sheets that are separated by a distance (dmin). Also disclosed herein are bioreactors that include a vessel with sides and a bottom, at least one opening in the vessel connected to a means for introducing a gas, and at least two scaffolds in the vessel oriented substantially vertically in the vessel. The disclosure also includes methods of culturing cells including incubating a suspension of cells in a disclosed bioreactor and introducing a gas through the at least one opening in the vessel. In some examples, the cells include microalgae, macroalgae, bacteria, fungi, insect cells, plant cells, or animal cells.Type: GrantFiled: November 25, 2015Date of Patent: March 31, 2020Assignees: Arizona Board of Regents on Behalf of the University of Arizona, Biopharmia ASInventors: Joel L. Cuello, Cody Brown, Roald A. Flo, Takanori Hoshino, Sara S. Kuwahara
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Patent number: 10598946Abstract: The present invention relates generally to stereoscopic displays, and more particularly, but not exclusively, to stereoscopic displays with addressable focus cues.Type: GrantFiled: July 23, 2019Date of Patent: March 24, 2020Assignee: THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Hong Hua, Xinda Hu
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Patent number: 10598939Abstract: Eye-tracked head-mounted displays are provide which, in one aspect, may utilize the same optics for eyetracking and image viewing, with a selected portion of the optics used for an eyetracking optical path and a selected portion of the display optics used for an image viewing optical path.Type: GrantFiled: April 10, 2019Date of Patent: March 24, 2020Assignees: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, AUGMENTED VISION, INCInventors: Hong Hua, Chunyu Gao