Abstract: The invention encompasses method of using quantitative PCR to detect fungal organisms in clinical and environmental samples to generate standards that allow the quantification of fungal organisms in the samples.
Type:
Grant
Filed:
May 12, 2014
Date of Patent:
September 6, 2016
Assignees:
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventors:
Cindy Liu, Sergey Kachur, Lance Price, Paul Keim
Abstract: The present invention provides assays, methods and kits that may be used to detect and differentiate MRSA isolates, e.g., USA100, USA300 and USA600 strains.
Type:
Grant
Filed:
September 7, 2012
Date of Patent:
May 17, 2016
Assignees:
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventors:
Paul Keim, Elizabeth Driebe, David Engelthaler, Jolene Bowers
Abstract: The invention pertains to sequences, methods, and kits useful in the identification of and differentiation between Burkholderia pseudomallei and Burkholderia mallei. The methods generally involve the addition of oligonucleotides to mixtures containing nucleic acid isolated from a sample and performing nucleic acid amplification on the mixture.
Type:
Grant
Filed:
May 19, 2011
Date of Patent:
May 17, 2016
Assignees:
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventors:
Jolene Bowers, David Engelthaler, Paul Keim
Abstract: Methods and kits used in the detection of variants of the Influenza virus are disclosed, including variants that are resistant to treatment with antiviral compositions.
Type:
Grant
Filed:
October 20, 2010
Date of Patent:
January 19, 2016
Assignees:
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventors:
Paul Keim, David Engelthaler, Elizabeth Driebe, Cindy Liu
Abstract: The present invention provides methods and kits that may be used to detect and quantify the presence of Coccidioides species. The methods include quantification PCR assays, and the kits and compositions include oligonucleotides used as primers and probes.
Type:
Grant
Filed:
October 6, 2011
Date of Patent:
September 8, 2015
Assignees:
The Translational Genomics Research Institute, The Arizona Board of Regents on Behalf of Northern Arizona University
Inventors:
David Engelthaler, Elizabeth Driebe, Paul Keim
Abstract: The compositions and methods relate to an organic polymer-inorganic particle sensor material for detecting analytes. Interactions between the polymer and the particles are affected by the presence of analyte, which displaces the polymer and increases its free volume. This change in free volume can be detected, e.g., using an embedded piezoresistive microcantilever (EPM) sensor. Analytes that can be detected include noxious substances, such as hydrogen cyanide gas and carbon monoxide.
Type:
Grant
Filed:
January 18, 2008
Date of Patent:
September 9, 2014
Assignees:
Cantimer, Inc., Arizona Board Of Regents For And On Behalf Of Northern Arizona University
Inventors:
Timothy L. Porter, Ray Stewart, Timothy L. Vail
Abstract: The invention encompasses method of using quantitative PCR to detect fungal organisms in clinical and environmental samples to generate standards that allow the quantification of fungal organisms in the samples.
Type:
Application
Filed:
May 12, 2014
Publication date:
September 4, 2014
Applicants:
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, Arizona Board Of Regents On Behalf Of Northern Arizona University
Inventors:
Cindy Liu, Sergey Kachur, Lance Price, Paul Keim
Abstract: Methods and kits used in the detection of the H1N1/09 influenza virus are provided. The methods include the use of nucleic acids to detect H1N1/09 generally as well as H1N1/09 variants resistant to antiviral compositions.
Type:
Grant
Filed:
November 1, 2010
Date of Patent:
August 19, 2014
Assignees:
The Translational Genomics Research Institute, Arizona Board of Regents on Behalf of Northern Arizona University
Inventors:
Paul Keim, Elizabeth Driebe, David Engelthaler
Abstract: The invention encompasses methods of using quantitative PCR to detect fungal organisms in clinical and environmental samples and to generate standards that allow the quantification of fungal organisms in the samples.
Type:
Grant
Filed:
January 26, 2011
Date of Patent:
May 13, 2014
Assignees:
The Translational Genomics Research Institute, Arizona Board of Regents on Behalf of Northern Arizona University
Inventors:
Cindy Liu, Sergey Kachur, Lance Price, Paul Keim
Abstract: The invention encompasses methods of using quantitative PCR to detect fungal organisms in clinical and environmental samples and to generate standards that allow the quantification of fungal organisms in the samples.
Type:
Application
Filed:
January 26, 2011
Publication date:
October 27, 2011
Applicants:
Arizona Board of Regents on Behalf of Northern Arizona University, THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
Abstract: Methods and kits used in the detection of variants of the Influenza virus are disclosed, including variants that are resistant to treatment with antiviral compositions.
Type:
Application
Filed:
October 20, 2010
Publication date:
April 21, 2011
Applicants:
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, THE ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventors:
PAUL KEIM, DAVID ENGELTHALER, ELIZABETH DRIEBE, CINDY LIU