Patents Assigned to Arizona Board of Regents, The University of Arizona
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Patent number: 10172908Abstract: The present invention provides compositions and methods for treating cognitive impairment or dysfunction in a subject. In particular, the present invention provides a method for using a composition comprising an angiotensin-(1-7) receptor agonist to treat cognitive dysfunction or impairment that is due to a various clinical conditions including, but not limited to, those associated with increase in inflammation, cytokine production, increases in reactive oxygen species, changes in expression of brain inflammatory related genes and/or in the expression of genes involved in learning and memory within the central nervous system of a subject.Type: GrantFiled: January 4, 2016Date of Patent: January 8, 2019Assignee: ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONAInventors: Meredith Hay, Carol Barnes, John Konhilas
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Publication number: 20180179144Abstract: The present invention provides a process for nitrating aromatic compounds without the need for a solid catalyst and/or any organic solvents and/or any other additives. A typical process includes combining or admixing a nitric acid and an anhydride compound under conditions sufficient to produce a reactive intermediate. The aromatic compound to be nitrated is then added to this reactive intermediate to produce a nitroaromatic compound. The nitroaromatic compound can be substituted with one or more, typically, one to three, and often one or two nitrate (—NO2) groups.Type: ApplicationFiled: January 18, 2016Publication date: June 28, 2018Applicant: Arizona Board of Regents for the University of ArizonaInventors: Bhumasamudram Jagadish, Eugene Mash
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Publication number: 20160135751Abstract: The present invention provides a system and a method for detecting a neuromotor disorder or condition in a subject using an electronic device that comprises an input device. The method generally involves determining input device usage characteristics of the subject and comparing the result to a reference input device usage characteristic.Type: ApplicationFiled: June 20, 2014Publication date: May 19, 2016Applicant: Arizona Board of Regents for the University of ArizonaInventors: Joseph S. Valacich, Jeffrey L. Jenkins, John Howie
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Publication number: 20100328742Abstract: The present invention provides a hologram which forms a light intensity distribution on a predetermined plane by using an incident light. The hologram includes a plurality of cells configured to control both a phase of a first polarized light component of the incident light and a phase of a second polarized light component. The plurality of cells are designed to form a portion in an overlap region in which a first light intensity distribution region formed on the predetermined plane by the first polarized light component and a second light intensity distribution region formed on the predetermined plane by the second polarized light component are superposed on each other. The phase of the first polarized light component is diffused in the portion formed in the overlap region.Type: ApplicationFiled: June 24, 2009Publication date: December 30, 2010Applicants: CANON KABUSHIKI KAISHA, ARIZONA BOARD OF REGENTS / UNIVERSITY OF ARIZONAInventors: Isao Matsubara, Yasuyuki Unno, William Dallas
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Patent number: 5437976Abstract: The present invention is directed to a multi-domain oligonucleotide ligand having multiple functions conferred by each of the domains. The ligand is bound to a solid phase matrix for use in both mRNA-affinity chromatography and as a priming matrix for generating matrix-bound cDNA from the mRNA bound to the matrix. The resultant cDNA was tested and found to function as a solid-phase template for PCR. This solid-phase template approach to PCR is demonstrated with oligo-d(T) paper. The functional domains are defined by polynucleotide sequences on the ligand to confer the different functions.Type: GrantFiled: August 8, 1991Date of Patent: August 1, 1995Assignee: Arizona Board of Regents, The University of ArizonaInventor: Joseph G. Utermohlen
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Patent number: 5055130Abstract: A method for recovering silver from a refractory manganese dioxide-silver ore. The ore is contacted with an effective amount of a culture of direct manganese-reducing Bacillus polymyxa bacteria. The ore-bacteria mixture is maintained at an approximately neutral pH until a sufficient amount of the manganese dioxide in the ore is reduced from Mn(IV) to Mn(II). The silver present in the ore is then recovered by conventional methods such as cyanide leaching.Type: GrantFiled: May 1, 1990Date of Patent: October 8, 1991Assignee: The Arizona Board of Regents/University of ArizonaInventors: Robert G. Arnold, Norval A. Sinclair, James E. Sharp
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Patent number: 4943586Abstract: A compound having pesticidal activity and which has the following general formula: ##STR1## wherein: R.sub.1 is selected from hydrogen, C.sub.1-6 alkyl, halogen, C.sub.1-6 alkoxy, C.sub.2-6 alkoxycarbonyl, amino, nitro, CF.sub.3, and C.sub.1-5 -(alkyl and dialkyl)-amino;X is a divalent hydrocarbon radical having 1 to 8 carbon atoms in its backbone, which may be interrupted by 1 or 2 of O or S, and which may be substituted by 1 or more halogens, C.sub.1-4 alkyl groups or C.sub.1-4 alkoxy groups;Y is O, S, CH.sub.2, SO, or SO.sub.2 ;Z is O, S, CH.sub.2, SO, or SO.sub.2 ;R.sub.2 is selected from hydrogen, halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.2-6 alkoxycarbonyl, amino, nitro, and CF.sub.3 ; andR.sub.3 is selected from hydrogen, halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.2-6 alkoxycarbonyl, amino, nitro, C.sub.1-5 -(alkyl and dialkyl)amino, and CF.sub.3.Type: GrantFiled: December 14, 1988Date of Patent: July 24, 1990Assignee: Arizona Board of Regents for the University of ArizonaInventors: William S. Bowers, Takeyoshi Sugiyama
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Patent number: 4294807Abstract: The flue gas desulfurization process using a lime or limestone slurry scrubbing solution producing used liquor containing calcium sulfite or sulfate (typically gypsum). Precipitated particles are removed by feeding the used scrubbing liquor to an agitated crystallization zone to grow crystals and directing part of the used scrubbing liquor from that zone to a quiescent crystallization zone, in which particles are settled back into the agitated zone. An underflow stream from the agitated zone containing large crystals is combined with an overflow stream from the quiescent zone, which combined stream is clarified with the fines being returned to the scrubber and the large crystals being removed as a waste product. Apparatus for performing the above process in which the agitated and quiescent crystallization zones form part of a single crystallization vessel, and the two zones are separated by a baffle.Type: GrantFiled: November 10, 1980Date of Patent: October 13, 1981Assignees: Electric Power Research Institute, Inc., The Arizona Board of Regents, The University of ArizonaInventor: Alan D. Randolph