Patents Assigned to Arizona Board of Regents, The University of Arizona
  • Patent number: 10172908
    Abstract: The present invention provides compositions and methods for treating cognitive impairment or dysfunction in a subject. In particular, the present invention provides a method for using a composition comprising an angiotensin-(1-7) receptor agonist to treat cognitive dysfunction or impairment that is due to a various clinical conditions including, but not limited to, those associated with increase in inflammation, cytokine production, increases in reactive oxygen species, changes in expression of brain inflammatory related genes and/or in the expression of genes involved in learning and memory within the central nervous system of a subject.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: January 8, 2019
    Assignee: ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONA
    Inventors: Meredith Hay, Carol Barnes, John Konhilas
  • Publication number: 20180179144
    Abstract: The present invention provides a process for nitrating aromatic compounds without the need for a solid catalyst and/or any organic solvents and/or any other additives. A typical process includes combining or admixing a nitric acid and an anhydride compound under conditions sufficient to produce a reactive intermediate. The aromatic compound to be nitrated is then added to this reactive intermediate to produce a nitroaromatic compound. The nitroaromatic compound can be substituted with one or more, typically, one to three, and often one or two nitrate (—NO2) groups.
    Type: Application
    Filed: January 18, 2016
    Publication date: June 28, 2018
    Applicant: Arizona Board of Regents for the University of Arizona
    Inventors: Bhumasamudram Jagadish, Eugene Mash
  • Publication number: 20160135751
    Abstract: The present invention provides a system and a method for detecting a neuromotor disorder or condition in a subject using an electronic device that comprises an input device. The method generally involves determining input device usage characteristics of the subject and comparing the result to a reference input device usage characteristic.
    Type: Application
    Filed: June 20, 2014
    Publication date: May 19, 2016
    Applicant: Arizona Board of Regents for the University of Arizona
    Inventors: Joseph S. Valacich, Jeffrey L. Jenkins, John Howie
  • Publication number: 20100328742
    Abstract: The present invention provides a hologram which forms a light intensity distribution on a predetermined plane by using an incident light. The hologram includes a plurality of cells configured to control both a phase of a first polarized light component of the incident light and a phase of a second polarized light component. The plurality of cells are designed to form a portion in an overlap region in which a first light intensity distribution region formed on the predetermined plane by the first polarized light component and a second light intensity distribution region formed on the predetermined plane by the second polarized light component are superposed on each other. The phase of the first polarized light component is diffused in the portion formed in the overlap region.
    Type: Application
    Filed: June 24, 2009
    Publication date: December 30, 2010
    Applicants: CANON KABUSHIKI KAISHA, ARIZONA BOARD OF REGENTS / UNIVERSITY OF ARIZONA
    Inventors: Isao Matsubara, Yasuyuki Unno, William Dallas
  • Patent number: 5437976
    Abstract: The present invention is directed to a multi-domain oligonucleotide ligand having multiple functions conferred by each of the domains. The ligand is bound to a solid phase matrix for use in both mRNA-affinity chromatography and as a priming matrix for generating matrix-bound cDNA from the mRNA bound to the matrix. The resultant cDNA was tested and found to function as a solid-phase template for PCR. This solid-phase template approach to PCR is demonstrated with oligo-d(T) paper. The functional domains are defined by polynucleotide sequences on the ligand to confer the different functions.
    Type: Grant
    Filed: August 8, 1991
    Date of Patent: August 1, 1995
    Assignee: Arizona Board of Regents, The University of Arizona
    Inventor: Joseph G. Utermohlen
  • Patent number: 5055130
    Abstract: A method for recovering silver from a refractory manganese dioxide-silver ore. The ore is contacted with an effective amount of a culture of direct manganese-reducing Bacillus polymyxa bacteria. The ore-bacteria mixture is maintained at an approximately neutral pH until a sufficient amount of the manganese dioxide in the ore is reduced from Mn(IV) to Mn(II). The silver present in the ore is then recovered by conventional methods such as cyanide leaching.
    Type: Grant
    Filed: May 1, 1990
    Date of Patent: October 8, 1991
    Assignee: The Arizona Board of Regents/University of Arizona
    Inventors: Robert G. Arnold, Norval A. Sinclair, James E. Sharp
  • Patent number: 4943586
    Abstract: A compound having pesticidal activity and which has the following general formula: ##STR1## wherein: R.sub.1 is selected from hydrogen, C.sub.1-6 alkyl, halogen, C.sub.1-6 alkoxy, C.sub.2-6 alkoxycarbonyl, amino, nitro, CF.sub.3, and C.sub.1-5 -(alkyl and dialkyl)-amino;X is a divalent hydrocarbon radical having 1 to 8 carbon atoms in its backbone, which may be interrupted by 1 or 2 of O or S, and which may be substituted by 1 or more halogens, C.sub.1-4 alkyl groups or C.sub.1-4 alkoxy groups;Y is O, S, CH.sub.2, SO, or SO.sub.2 ;Z is O, S, CH.sub.2, SO, or SO.sub.2 ;R.sub.2 is selected from hydrogen, halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.2-6 alkoxycarbonyl, amino, nitro, and CF.sub.3 ; andR.sub.3 is selected from hydrogen, halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.2-6 alkoxycarbonyl, amino, nitro, C.sub.1-5 -(alkyl and dialkyl)amino, and CF.sub.3.
    Type: Grant
    Filed: December 14, 1988
    Date of Patent: July 24, 1990
    Assignee: Arizona Board of Regents for the University of Arizona
    Inventors: William S. Bowers, Takeyoshi Sugiyama
  • Patent number: 4294807
    Abstract: The flue gas desulfurization process using a lime or limestone slurry scrubbing solution producing used liquor containing calcium sulfite or sulfate (typically gypsum). Precipitated particles are removed by feeding the used scrubbing liquor to an agitated crystallization zone to grow crystals and directing part of the used scrubbing liquor from that zone to a quiescent crystallization zone, in which particles are settled back into the agitated zone. An underflow stream from the agitated zone containing large crystals is combined with an overflow stream from the quiescent zone, which combined stream is clarified with the fines being returned to the scrubber and the large crystals being removed as a waste product. Apparatus for performing the above process in which the agitated and quiescent crystallization zones form part of a single crystallization vessel, and the two zones are separated by a baffle.
    Type: Grant
    Filed: November 10, 1980
    Date of Patent: October 13, 1981
    Assignees: Electric Power Research Institute, Inc., The Arizona Board of Regents, The University of Arizona
    Inventor: Alan D. Randolph