Abstract: Methods for light-induced electroplating of aluminum are disclosed herein. Exemplary methods may comprise preparing an ionic liquid comprising aluminum chloride (AlCl3) and an organic halide, placing the silicon substrate into the ionic liquid, illuminating the silicon substrate, the illumination passing through the ionic liquid, and depositing aluminum onto the silicon substrate via a light-induced electroplating process, wherein the light-induced electroplating process utilizes an applied current that does not exceed a photo-generated current generated by the illumination.

Abstract: Methods and systems, including those employing machine learning, utilizing one or more algorithms for relating the structure of a molecule in a library to its function are described. Embodiments described herein relate structure to function by considering the covalent structure of the molecule, the components of that structure that are common to many molecules in the library, and the properties of those components as they relate to the function in question. Applications include, for example, enhancement and amplification of the diagnostic and prognostic signals provided by peptide arrays for use in analyzing the profile of antibodies in the blood produced in response to a disease, condition or treatment.

Abstract: The instant disclosure is directed to compositions comprising an encapsulated spheroid, and methods of making and using the same. A composition may comprise a spheroid comprising a plurality of cells and aminoglycoside antibiotic-derived hydrogel beads, wherein the spheroid is encapsulated by the aminoglycoside antibiotic-derived hydrogel beads to form an encapsulated spheroid. A method may comprise administering the composition to a subject in need thereof. Another method may comprise administering a compound to the encapsulated spheroid. A method of creating an encapsulated spheroid may comprise coating a surface with an aminoglycoside antibiotic-derived hydrogel, culturing a plurality of cells on the surface, thereby creating a spheroid, and encapsulating the spheroid with a plurality of aminoglycoside antibiotic-derived hydrogel beads.

Abstract: Methods and systems for screening therapeutic compositions for the treatment of age-related macular degeneration (AMD) or for the prevention of progression of AMD, wherein retinal pigment epithelium cells (RPE) are cultured and the level of hypoxia-induced exosome release from the RPE cells is subsequently measured. In the present invention, the level of hypoxia-induced exosome release can be correlated with AMD onset and severity.

Abstract: Assessing a thermal conductivity of a viscoelastic material in a steady state using a conduction method includes i) allowing a sample of the viscoelastic material to reach thermal equilibrium in a liquid at a first temperature, ii) assessing a heat flow of the sample at the first temperature, iii) repeating i) and ii) at one or more additional temperatures, and iv) assessing the thermal conductivity of the viscoelastic material based on the heat flow of the sample at the first temperature and the one or more additional temperatures, a cross-sectional area of the sample, and a temperature-thickness gradient of the sample at thermal equilibrium.

Abstract: Various embodiments of a system and associated method for generating a valid mapping for a computational loop on a CGRA are disclosed herein. In particular, the method includes generating randomized schedules within particular constraints to explore greater mapping spaces than previous approaches. Further, the system and related method employs a feasibility test to test validity of each schedule such that mappings are only generated from valid schedules.

Abstract: A phosphorescent emitter or delayed fluorescent and phosphorescent emitters represented by Formula I or Formula II, where M is platinum or palladium.

Abstract: A system for failure detection tools is disclosed. The system may include at least one user device, an application server, and a failure detection system, each of which may be in communication with one or more of the others via at least one network. The failure detection system may receive first data from a data source, process the first data to generate second data, apply a statistical modeling algorithm to make a prediction relating to the first data or the second data, and communicate data relating to the prediction and/or a trend related to the first data or the second data to the user device for displaying at least a portion of the data relating to the prediction and/or the trend on a display of the user device.

Abstract: A light emitting device includes a transparent organic light emitting device and a quarter-wave plate. The transparent organic light emitting device includes a chiral complex emitter and produces circularly polarized light, and the quarter-wave plate converts the circularly polarized light into linearly polarized light. Generating linearly polarized light includes generating circularly polarized light via a transparent organic light emitting device including a chiral complex emitter, and passing the circularly polarized light through a quarter-wave plate to yield linearly polarized light.

Abstract: Various embodiments of a system and methods for audio source separation via multi-scale feature learning are disclosed.

Abstract: A two-step thermochemical reactor and method are disclosed. The reactor includes a housing and a reactor cavity formed within, and surrounded by, thermal insulation within the housing. The reactor cavity includes at least one unit cell, each cell having an electric heat source and a reactive material. The reactor also includes a feedstock inlet and a product outlet in fluid communication with the reactor cavity. The reactor also includes a reducing configuration, with the inlet being closed and the electric heat source of each unit cell being driven to thermally reduce the reactive material at a first temperature, releasing oxygen into the cavity. The reactor also has a splitting configuration where the reactive material is at a second temperature that is lower than the first, the feedstock inlet open and introducing feedstock gas into the cavity to reoxidize the reactive material and split into a product gas.

Abstract: A safety-guaranteed control system for automated vehicles (AVs) considers both vehicle and tire stabilities on varying road conditions. Conventional AV control systems may not be sufficient to adequately handle control-dependent and time-varying safety constraints. The system integrates control-dependent barrier functions (CDBF) and time-varying CBFs (TCBFs) with control Lyapunov functions (CLFs) in a quadratic programming problem.

Abstract: The invention relates to compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens of interest.

Abstract: A system and method for modulating optogenetic vagus neurons in a noninvasive and transcutaneous manner is disclosed. The system and method comprises a two-dimensional array of organic light emitting diodes (OLEDs), a voltage-generating unit, a control unit, and a feedback loop. The array is placed on a subject's outer ear. Because the array is flexible, it can be closely placed on the skin of the outer ear. The array can deliver optical therapy and monitor heart rate variability (HRV) of the subject simultaneously, and the pixels of the array can be individually addressed. The voltage-generating unit generates pulsed voltage to the OLEDs. The control unit is connected to the array and controls the array and therapeutic patterns. The feedback loop uses the HRV to identify the therapeutic patterns.

Abstract: A system and method for the automatic stimulation of a vagus nerve for post-stroke rehabilitation is disclosed. The system includes an application subsystem having an electrode positioned to stimulate the vagus nerve and coupled to a user outside of a surgical setting. The system also includes a waveform generator communicatively coupled to the electrode, and a triggering subsystem including a receiver configured to detect the presence of a tag. The triggering subsystem is communicatively coupled to waveform generator and is configured to automatically trigger the stimulation of the vagus nerve upon detecting the presence of the tag. The tag is located proximate a rehabilitation context such that the tag is detected when the user is using the rehabilitation context, resulting in the vagus nerve of the user being automatically stimulated by the electrode in response to the user's post-stroke rehabilitation training.

Abstract: A zwitterionic polysulfone formed from an allyl-containing monomer, a phenol-containing monomer, and an aryl-halide-containing monomer. The zwitterionic polysulfone may be incorporated into a desalination membrane.

Abstract: Described herein are means for generation of self-taught generic models, named Models Genesis, without requiring any manual labeling, in which the Models Genesis are then utilized for the processing of medical imaging. For instance, an exemplary system is specially configured for learning general-purpose image representations by recovering original sub-volumes of 3D input images from transformed 3D images. Such a system operates by cropping a sub-volume from each 3D input image; performing image transformations upon each of the sub-volumes cropped from the 3D input images to generate transformed sub-volumes; and training an encoder-decoder architecture with skip connections to learn a common image representation by restoring the original sub-volumes cropped from the 3D input images from the transformed sub-volumes generated via the image transformations.

Abstract: Method and system for on-chip processing to obtain an EDOF image combines interferometry and imaging so the two operations do not interfere with one another but, rather, work together to create an in-focus, true color image of a three-dimensional object. This image has no significant artifacts and requires only limited processing. In addition, a coarse depth map is created in the process which may also be helpful in subsequent usage of the acquired image. A CMOS pixel-array sensor includes circuitry to implement processing at the pixel level.

Abstract: Disclosed are compositions for generating an immune response against human immunodeficiency virus (HIV) and their methods of uses.

Abstract: A method estimates an intention of a lead vehicle by an ego vehicle. The method includes: (a) receiving, from at least one of a first plurality of sensors coupled to the ego vehicle, information associated with a parametric variable, (b) selecting a partition of an operating region of the parametric variable based on the parametric variable information, wherein the operating region includes a predetermined range of values for the parametric variable, wherein the partition includes a subset of the predetermined range of values and being associated with a predetermined ego vehicle input, and wherein the predetermined vehicle input includes at least one value for a parameter corresponding to dynamics of the ego vehicle, and (c) causing a vehicle control system of the ego vehicle to perform a vehicle maneuver based on the predetermined ego vehicle input.