Abstract: Provided herein are methods of modulating temperature in detection fields and producing analyte imaging data. In some embodiments, the methods include introducing an incident light toward a second surface of a substrate to induce a plasmonic wave proximal to a first surface of the substrate such that a temperature in a selected heating space within the detection field is substantially uniformly changed to a selected temperature. Additional methods as well as related systems and computer readable media are also provided.

Abstract: Various embodiments of a variable geometry quadrotor with a compliant frame are disclosed, which adapts to tight spaces and obstacles by way of passive rotation of its arms.

Abstract: An auscultation system comprises an auscultation device comprising a wearable apparatus positionable proximate to a lung, a plurality of audio sensors embedded in the wearable apparatus configured to record lung sounds, wherein the plurality of audio sensors are positioned at locations of the wearable apparatus corresponding to lung auscultation points, and a computing system communicatively connected to the auscultation device, comprising a processor and a non-transitory computer-readable medium with instructions stored thereon, which when executed by a processor, perform steps comprising, establishing a background noise spectrum, recording a lung sound spectrum via the auscultation device for a period of time, calculating a background subtracted lung sound spectrum by subtracting the background noise spectrum from the measured lung sound spectrum, analyzing the background subtracted lung sound spectrum to produce an auscultation result, and providing the auscultation result to a practitioner to assist in pr

Abstract: A Processing-in-Memory (PIM) design is disclosed that converts any memory sub-array based on non-volatile resistive bit-cells into a potential processing unit. The memory includes the data matrix stored in terms of resistive states of memory cells. Through modifying peripheral circuits, the address decoder receives three addresses and activates three memory rows with resistive bit-cells (i.e., data operands). In this way, three bit-cells are activated in each memory bit-line and sensed simultaneously, leading to different parallel resistive levels at the sense amplifier side. By selecting different reference resistance levels and a modified sense amplifier, a full-set of single-cycle 1-/2-3-input reconfigurable complete Boolean logic and full-adder outputs could be intrinsically readout based on input operand data in the memory array.

Abstract: Described here are systems and methods for generating and implementing a hybrid machine learning and mechanistic model to produce biological feature maps, or other measurements of biological features, based on an input of multiparametric magnetic resonance or other images. The hybrid model can include a combination of a machine learning model and a mechanistic model that takes as an input multiparametric MRI, or other imaging, data to generate biological feature maps (e.g., tumor cell density maps), or other measures or predictions of biological features (e.g., tumor cell density). The hybrid models have capabilities of learning individual-specific relationships between imaging features and biological features.

Abstract: Solvent free epoxy system that includes: a hardener compound H comprising: a molecular structure (Y1—R1—Y2), wherein R1 is an ionic moiety Y1 is a nucleophilic group and Y2 nucleophilic group; and an ionic moiety A acting as a counter ion to R1; and an epoxy compound E comprising: a molecular structure (Z1—R2—Z2), wherein R2 is an ionic moiety, Z1 comprises an epoxide group, and Z2 comprises an epoxide group; and an ionic moiety B acting as a counter ion to R2. In embodiments, the epoxy compound E and/or the hardener H is comprised in a solvent-less ionic liquid. The systems can further include accelerators, crosslinkers, plasticizers, inhibitors, ionic hydrophobic and/or super-hydrophobic compounds, ionic hydrophilic compounds, ionic transitional hydrophobic/hydrophilic compounds, biological active compounds, and/or plasticizer compounds. Polymers made from the disclosed epoxy systems and their methods of used.

Abstract: In certain embodiments, the present invention provides a poultry vaccine comprising an antigenic protein comprising a PlcC protein unit that is operably linked to a peptide linker that is operably linked to a NetB protein unit, where the vaccine is effective in stimulating a protective cellular and/or humoral immune response to C. perfringens. Methods are also provided for making the vaccine and for vaccinating poultry by administering such a vaccine.

Abstract: A wireless multi-channel implantable device. In some embodiments, the system includes: a wireless reception element, for receiving power wirelessly through tissue of a subject; a power management and storage circuit, for storing a portion of the received power; and a control circuit for controlling the delivery of current from the power management and storage circuit to each of a plurality of stimulation electrodes individually, based on a modulation of the received power.

Abstract: Iridium, rhodium, and platinum complexes suitable for use as phosphorescent emitters or as delayed fluorescent and phosphorescent emitters having the following structures:

Abstract: Provided herein are methods of detecting exosomes, including unlabeled exosomes. In some embodiments, the methods include disposing a fluidic sample that comprises a plurality of exosomes in a chamber that is positioned at least partially within a fluidic device in which an inner surface of the chamber comprises a first set of exosome binding moieties that are capable of binding the exosomes. In some embodiments, the methods also include binding a portion of the plurality of exosomes to a portion of the first set of exosome binding moieties to produce surface-bound exosomes, introducing an incident light toward the inner surface of the chamber prior to, concurrent with, and/or after, producing the surface-bound exosomes, and detecting light scattered by the surface-bound exosomes to produce a set of exosome imaging data. Related fluidic devices, systems, and computer readable media are also provided.

Abstract: An additive manufacturing process for forming a metallic layer on the surface of the substrate includes fabricating a substrate from a polymerizable composition by a stereolithographic process, and contacting the reactive surface with an aqueous solution including a metal precursor. The metal precursor includes a metal, and the polymerizable composition includes a multiplicity of multifunctional components. Each multifunctional component includes a reactive moiety extending from a surface of the substrate to form a reactive surface. An interface between the reactive surface and the aqueous solution is selectively irradiated to form nanoparticles including the metal in a desired pattern. The nanoparticles are chemically coupled to the reactive surface by reactive moieties, thereby forming a metallic layer on the surface of the substrate.

Abstract: A full-stack neural network obfuscation framework obfuscates a neural network architecture while preserving its functionality with very limited performance overhead. The framework includes obfuscating parameters or “knobs”, including layer branching, layer widening, selective fusion and schedule pruning, that increase the number of operators, reduce/increase the latency, and number of cache and DRAM accesses. In addition, a genetic algorithm-based approach is adopted to orchestrate the combination of obfuscating knobs to achieve the best obfuscating effect on the layer sequence and dimension parameters so that the architecture information cannot be successfully extracted.

Abstract: Provided herein are qPCR-based methods for quantitatively detecting and differentiating between live and dead pathogenic bacteria such as carbapenem-resistant Enterobacteriaceae (CRE). Also provided herein are simple, fast, and reliable genomic DNA extraction methods with improved efficiency.

Abstract: Described herein are systems and methods for the depolymerization of polyethylene-based plastics. In one embodiment, a method is disclosed that comprises combining a polyethylene-based plastic with a solvent in a reactor to generate a plastic solvent mixture, heating the plastic solvent mixture in the reactor, and fractionating the plastic solvent mixture into a gas phase product, a solid phase product, and a liquid phase product. In another embodiment, a system is disclosed that comprises a solvent, and a reactor configured to receive the polyethylene-based plastic and the solvent and convert the polyethylene-based plastic into a gas phase product, a solid phase product, and a liquid phase product, the reactor being configured to operate at a temperature greater than 275° C. and at a pressure greater than 2 megapascals.

Abstract: Provided herein are systems and related methods of performing solar field and receiver inspections based on polarimetric-enhanced imaging.

Abstract: A computer-implemented SynF (Synthetic Infrastructure) model is designed to estimate the location and characteristics of urban water and power distribution networks, estimate how those networks are interconnected and connect to buildings and transportation systems, and assess how failures propagate within and across the systems. The model was designed using Phoenix metro area cities but has been extended to other cities.

Abstract: This disclosure includes systems and methods for extracting water vapor from atmospheric air and, more particularly, but not by way of limitation, systems and methods for optimizing liquid water production from air, in some instances, taking into account diurnal variations. The systems comprise an adsorption zone and a desorption zone, an actuator to move a desiccant between the adsorption zone and the desorption zone. The liquid water production is optimized based, at least in part, on measurements of one or more of: an ambient air temperature, ambient air relative humidity, and a level of solar insolation.

Abstract: A method for deep learning video microscopy-based antimicrobial susceptibility testing of a bacterial strain in a sample by acquiring image sequences of individual bacterial cells of the bacterial strain in a subject sample before, during, and after exposure to each antibiotic at different concentrations. The image sequences are compressed into static images while preserving essential phenotypic features. Data representing the static images is input into a pre-trained deep learning (DL) model which generates output data; and antimicrobial susceptibility for the bacterial strain is determined from the output data.

Abstract: Provided herein are methods of detecting and measuring disease-associated analytes such as proteins and antibodies in a sweat sample. Also provided are methods of determining and monitoring the disease state or physiological condition of a subject using small sweat samples.

Abstract: Platinum complexes suitable for use as phosphorescent emitters or as delayed fluorescent and phosphorescent emitters having the following structure: