Patents Assigned to Arkansas State University
  • Patent number: 12319713
    Abstract: 3,4-thiazolo steroids are provided herein. Also provided herein are methods of making and using the same for the inhibition of cell proliferation or the killing of cells.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: June 3, 2025
    Assignee: Arkansas State University—Jonesboro
    Inventor: Mohammad Abrar Alam
  • Patent number: 11970473
    Abstract: Nootkatone derivatives comprising a fused thiazole ring and methods of using the same are disclosed herein.
    Type: Grant
    Filed: March 31, 2022
    Date of Patent: April 30, 2024
    Assignee: Arkansas State University—Jonesboro
    Inventor: Mohammad Abrar Alam
  • Patent number: 11773399
    Abstract: Methods of increasing production, stability or activity of a target polypeptide are provided herein. The method includes increasing the level of an antioxidant in a cell comprising a polynucleotide encoding the target polypeptide. Also provided are cells and transgenic organisms produced using the methods described herein. Methods of treating a subject with a condition treatable by administration of the target polypeptide are also disclosed. Finally methods and compositions for transiently increasing antioxidants in plant cells are provided.
    Type: Grant
    Filed: October 22, 2010
    Date of Patent: October 3, 2023
    Assignee: Arkansas State University—Jonesboro
    Inventors: Maureen C. Dolan, Argelia Lorence, Giuliana Medrano
  • Patent number: 11135547
    Abstract: An air-cooled condensing heat exchanger system (“ACHX”) installed in a fossil power plant flue gas treatment system recovers water and low temperature waste heat from boiler flue gas for advanced coal fired power plant applications. More particularly, the ACHX system recovers water from combustion flue gas by phase change. To recover water from flue gas, the ACHX system uses ambient air from an air intake installed on the stack to cool down the flue gas in the ACHX.
    Type: Grant
    Filed: September 30, 2017
    Date of Patent: October 5, 2021
    Assignee: Arkansas State University—Jonesboro
    Inventor: Kwangkook Jeong
  • Patent number: 11124800
    Abstract: Ascorbate protects tissues against damage caused by reactive oxygen species (ROS) produced through normal metabolism or generated from stress. The inositol route to AsA involves four enzymes: myo-inositol oxygenase, glucuronate reductase, gluconolactonase (GNL), and L-gulono-1,4-lactone oxidase (GulLO). Eighteen putative GNLs were identified in Arabidopsis, one of which, AtGNL, is interesting because it possesses a chloroplastic signal peptide. Knockouts on this gene had lower foliar AsA and stunted growth compared to controls. The functional gene restored the phenotype of the knockouts, and those plants had higher AsA content, enhanced photosynthetic capacity, and higher seed yield.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: September 21, 2021
    Assignee: Arkansas State University—Jonesboro
    Inventors: Argelia Lorence, Jessica Patricia Yactayo-Chang
  • Patent number: 10704052
    Abstract: The process and system led to the identification of prenyltransferase genes from elicitor-treated peanut hairy roots. One of the prenyltransferases, AhR4DT-1 catalyzes a key reaction involved in the biosynthesis of prenylated stilbenoids, in which resveratrol is prenylated at its C-4 position to form arachidin-2, while another, AhR3?DT-1, was able to add the prenyl group to C-3? of resveratrol. Each of these prenyltransferases has a high specificity for stilbenoid substrates, and their subcellular location in the plastid was confirmed by fluorescence microscopy. Structure analysis of the prenylated stilbenoids suggest that these two prenyltransferase activities represent the first committed steps in the biosynthesis of a large number of prenylated stilbenoids and their derivatives in peanut.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: July 7, 2020
    Assignees: Arkansas State University—Jonesboro, Indiana University Research and Technology Corporation
    Inventors: Luis Fabricio Medina-Bolivar, Tianhong Yang, Keithanne Mockaitis
  • Patent number: 10596153
    Abstract: New 1,3-dipenyl pyrazole derived azomethines and N-aryl amines have been synthesized. These anti-MRSA agents combat MRSA and other infections. These azomethine and N-arylamine derivatives of benzoic acid provide combat MRSA and other infections.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: March 24, 2020
    Assignee: Arkansas State University-Jonesboro
    Inventor: Mohammad Abrar Alam
  • Patent number: 10543434
    Abstract: The system and method spatially predict the condensation of water and acid from the flue gas in the condensing heat exchanger installed in fossil power plant flue gas treatment system or similar environment. By modifying the operational conditions, the heat exchanger can control rates and areas of condensations. The system and method adjust either the cooling water temperature or the flowrate ratio of flue gas to cooling water to control the condensation rates of water or acids. The system and method also estimate actual coverage areas to apply for anti-corrosive coating onto the tube or duct surfaces to resist corrosion due to acid condensation. The system and method also optimize or customize condensation rates of water and acids in boiler flue gas under operating conditions given at a power plant.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: January 28, 2020
    Assignee: Arkansas State University—Jonesboro
    Inventor: Kwangkook Jeong
  • Patent number: 10318672
    Abstract: The system effectively manipulates the operation of a charged particle flow device by approximating the total force on each ion during a trajectory calculation. The system applies the method in massively parallel general-purpose computing with GPU (GPGPU) to test its performance in simulations with thousands to over a million ions. The method calculates the forces on an ion using ions within an active region near the ion of interest. To decrease computation time, the method approximates the forces by calculating the ion-ion interactions within a first zone and the ion-ion cloud interactions within a second zone. The system adjusts settings of the charged particle flow device to affect the flow and positioning of the charged particles. Such setting may include adjusting the positioning of the charged plates, adjusting the voltage of the plates, and adjusting the pressure within the charged particle flow device.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: June 11, 2019
    Assignee: Arkansas State University—Jonesboro
    Inventors: Hideya Koizumi, Kenichiro Saito
  • Patent number: 10279366
    Abstract: The nozzle clog detection device, system, and method detect if a liquid flows through a nozzle via conduction of electricity. The clog detector provides an open circuit at an opening between two conductors. The two conductors are placed in the flow path of a liquid flowing from a nozzle. The liquid from the nozzle conducts electricity. The liquid flowing through the opening between the conductors closes the circuit. An alert system notifies the user whether liquid is flowing through the nozzle. The system detects flow of liquid from multiple nozzles and identifies the nozzles from which liquid flows. A break in the circuit at the opening between the conductors indicates that the liquid is not flowing sufficiently enough to close the circuit.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: May 7, 2019
    Assignee: Arkansas State University—Jonesboro
    Inventors: Peter Ako Larbi, Chin Nee Vong
  • Publication number: 20190117839
    Abstract: Decellularized plant tissues and the use of these plant tissues as scaffolds are disclosed herein. Particularly, decellularized plant tissues are functionalized such to allow for human cell adhesion, thereby allowing for their use as scaffolds for human cells. These scaffolds can then be used in a number of applications/markets, including as research tools for tissue engineering, regenerative medicine, and basic cellular biology.
    Type: Application
    Filed: March 14, 2017
    Publication date: April 25, 2019
    Applicants: Wisconsin Alumni Research Foundation, Arkansas State University - Jonesboro, Worcester Polytechnic Institute
    Inventors: William L. MURPHY, Gianluca FONTANA, Joshua GERSHLAK, Glenn GA UDETTE, Pam WEATHERS, Tanja DOMINKO, Marsha ROLLE, Sarah HERNANDEZ, Carol CRAMER, Fabricio MEDINA-BOLIVAR
  • Patent number: 10144913
    Abstract: A method or process to increase the production of products of interest in plant material including plant cultures, such as, for example, cell suspension cultures, root cultures, and hairy root cultures is provided. In one embodiment, the method is to contacting the plant material with a precursor or xenobiotic when producing a product of interest from a plant. In another embodiment the plant material is also contacted with a trapping agent. The process may also provide for contacting an elicitor of the product of interest with the plant material. An embodiment provides for contacting an elicitor, precursor and trapping agent with the plant material. The ability to produce novel compounds such as glucosides and glucuronides is provided.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: December 4, 2018
    Assignee: Arkansas State University-Jonesboro
    Inventors: Luis Fabricio Medina-Bolivar, Tianhong Yang
  • Patent number: 10010810
    Abstract: An integrated reaction condensing heat exchanger system (“IRCHX”) may be installed in a fossil power plant flue gas treatment system. More particularly, the IRCHX system may be used for recovering water from combustion flue gas by phase change to reduce fresh water consumption in fossil power plants including coal-, oil- and gas-fired plants. To recover water from flue gas, the IRCHX system may be installed in a current flue gas treatment system in a new or existing power plant, which allows power plants to save fresh water consumption up to 20%. Additionally, it benefits: 1) low temperature heat recovery after economizer, 2) lower exhaust temperature of flue gas at stack, 3) lower moisture contents in exhaust flue gas at stack, and 4) reduced acid emission in flue gas at stack.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: July 3, 2018
    Assignee: Arkansas State University—Jonesboro
    Inventor: Kwangkook Jeong
  • Patent number: 9866793
    Abstract: An intelligent sensor assisted system that dynamically adapts to the video streaming needs of a network or sub networks of users in order to facilitate collaboration. This automated audio/video distribution system includes an identifier detector that allows the system to intelligently activate the cameras/audio devices located at a zone according to the user's needs. The system detects an identifier that is associated with a user. The system identifies all users in the cyberspace associated with the identifier. The system captures the audio/video of the user's activities at the zone. The system then transmits the audio/video feed to remote users in the cyberspace who share the same identifier.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: January 9, 2018
    Assignee: Arkansas State University—Jonesboro
    Inventors: Farhad Moeeni, Keane McGough
  • Patent number: 9783817
    Abstract: A method of expressing heterologous expansin in a plant cell is provided where a nucleic acid molecule encoding expansin is introduced into the plant cell and in an embodiment is operably linked to a promoter preferentially expressing in the seed tissue of the plant, and in another embodiment is linked to a promoter preferentially expressing in the embryo tissue of the seed. An embodiment provides the nucleic acid molecule is operably linked to a second nucleic acid molecule that directs expression to the endoplasmic reticulum, vacuole or cell wall. Plants and plant parts expressing expansin are provided. An assay for detection of expansin activity is also provided.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: October 10, 2017
    Assignee: Arkansas State University
    Inventors: Elizabeth E. Hood, Sangwoong Yoon
  • Patent number: 9638666
    Abstract: The invention is essentially a sequential (“DMA”) apparatus using a novel arrangement of at least three electrodes and at least two block electrodes to produce a DMA apparatus having at least two sequential DMA regions between pairs of adjacent electrode walls within the same housing. This apparatus is used to improve the transfer of particles into the subsequent DMA region without a vacuum or pump, and to improve the separation of target particles from non-target particles and concentration and collection of the target particles.
    Type: Grant
    Filed: January 18, 2016
    Date of Patent: May 2, 2017
    Assignee: Arkansas State University—Jonesboro
    Inventor: Hideya Koizumi
  • Patent number: 9598707
    Abstract: A method to increase the production of products of interest in plant material including plant cultures, such as, for example, cell suspension cultures, root cultures, and hairy root cultures is provided. In one embodiment, the method is to contacting the plant material with a precursor or xenobiotic when producing a product of interest from a plant. In another embodiment the plant material is also contacted with a trapping agent. The process may also provide for contacting an elicitor of the product of interest with the plant material. An embodiment provides for contacting an elicitor, precursor and trapping agent with the plant material. The ability to produce novel compounds such as glucosides and glucuronides is provided.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: March 21, 2017
    Assignee: Arkansas State University-Jonesboro
    Inventors: Luis Fabricio Medina-Bolivar, Tianhong Yang
  • Patent number: 9313455
    Abstract: An intelligent sensor assisted system that dynamically adapts to the video streaming needs of a network or sub networks of users in order to facilitate collaboration. This automated audio/video distribution system includes an RFID sensor system that allows the system to intelligently activate the cameras/audio devices located at a zone according to user's needs. The system detects an RFID tag that is associated with a user. The system identifies a group ID of the RFID tag. The system identifies all users in the cyberspace that belong to the group. The system activates the streaming of audio/video to capture the user's activities at the zone. The system then transmits the audio/video feed to remote users in the cyberspace who share the same Group ID.
    Type: Grant
    Filed: April 9, 2015
    Date of Patent: April 12, 2016
    Assignee: Arkansas State University—Jonesboro
    Inventors: Farhad Moeeni, Keane McGough
  • Patent number: 9239279
    Abstract: The invention is essentially a sequential (“DMA”) apparatus using a novel arrangement of at least three electrodes and at least two block electrodes to produce a DMA apparatus having at least two sequential DMA regions between pairs of adjacent electrode walls within the same housing. This apparatus is used to improve the transfer of particles into the subsequent DMA region without a vacuum or pump, and to improve the separation of target particles from non-target particles and concentration and collection of the target particles.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: January 19, 2016
    Assignee: Arkansas State University—Jonesboro
    Inventor: Hideya Koizumi
  • Patent number: 9095598
    Abstract: The present invention generally provides stilbenoid derivatives and methods for using stilbenoid derivatives to modulate the activity of cannabinoid receptors or scavenge reactive nitrogen species.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: August 4, 2015
    Assignees: The Board of Trustees of the University of Arkansas, Arkansas State University—Jonesboro
    Inventors: Anna Radominska-Pandya, Paul L. Prather, Luis Fabricio Medina-Bolivar, Philip R. Mayeux