Patents Assigned to Arkion Life Sciences LLC
  • Publication number: 20130217098
    Abstract: A recombinant yeast that makes an isoprenoid compound is provided. The yeast comprises an endogenous mevalonate pathway comprising (i) an enzyme that converts acetyl-CoA to acetoacetyl-CoA, (ii) an enzyme that converts acetoacetyl-CoA to hydroxymethylglutaryl-CoA, (iii) an enzyme that converts hydroxymethylglutaryl-CoA to mevalonic acid, (iv) an enzyme that converts mevalonic acid to phosphomevalonic acid, (v) an enzyme that converts phosphomevalonic acid to phosphomevalonate, and (vi) an enzyme that converts phosphomevalonate to isopentenyl pyrophosphate. The yeast further comprises heterologous nucleic acid sequences encoding an enzyme that converts hydroxymethylglutaryl-CoA to mevalonic acid, an enzyme that converts mevalonic acid to phosphomevalonic acid, an enzyme that converts phosphomevalonic acid to phosphomevalonate, and an enzyme that converts phosphomevalonate to isopentenyl pyrophosphate.
    Type: Application
    Filed: April 17, 2013
    Publication date: August 22, 2013
    Applicant: Arkion Life Sciences, LLC
    Inventor: Arkion Life Sciences, LLC
  • Patent number: 8241888
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: August 14, 2012
    Assignee: Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Publication number: 20110195470
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Application
    Filed: April 18, 2011
    Publication date: August 11, 2011
    Applicant: ARKION LIFE SCIENCES, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7927861
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: April 19, 2011
    Assignee: Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7927862
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: April 19, 2011
    Assignee: Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7910560
    Abstract: A method for increasing breast meat yield in avians by treating the poultry with an effective amount of natamycin. The effective amount of natamycin can be added to the avian's feed wither directly or in the form of a premix containing a carrier.
    Type: Grant
    Filed: May 4, 2004
    Date of Patent: March 22, 2011
    Assignee: Arkion Life Sciences LLC
    Inventor: A. Franklin Carter
  • Patent number: 7842497
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: November 30, 2010
    Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7838279
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: November 23, 2010
    Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7732161
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: June 8, 2010
    Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7718417
    Abstract: The invention provides a biological method of producing isoprenoids.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: May 18, 2010
    Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLC
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 7488493
    Abstract: A performance aid for increasing the effectiveness of a bioactive agent, and a composition including both the performance and the bioactive agent. The performance aid increases the effectiveness of the bioactive agent by providing a composition that adheres well to a surface but also increases transferability of the bioactive agent to a target animal that contacts the treated surface.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: February 10, 2009
    Assignee: Arkion Life Sciences, LLC
    Inventors: Kenneth E. Ballinger, Jr., Michele Santer
  • Publication number: 20090017520
    Abstract: The present invention relates to a method and materials for producing glucosamine by fermentation of a genetically modified microorganism. Included in the present invention are genetically modified microorganisms useful in the present method for producing glucosamine, as well as recombinant nucleic acid molecules and the proteins produces by such recombinant nucleic acid molecules.
    Type: Application
    Filed: June 22, 2007
    Publication date: January 15, 2009
    Applicant: Arkion Life Sciences LLC d/b/a Bio-Technical Resources
    Inventors: Alan Berry, Richard P. Burlingame, James R. Millis
  • Patent number: 7332304
    Abstract: A biosynthetic method for producing glucosamine and N-acetylglucosamine is disclosed. Such a method includes the fermentation of a genetically modified microorganism to produce glucosamine and/or N-acetylglucosamine. Also disclosed are genetically modified microorganisms that are useful for producing glucosamine and N-acetylglucosamine. In addition, methods of recovering N-acetylglucosamine that has been produced by a fermentation process, including methods that result in N-acetylglucosamine of high purity, are described. Also disclosed is a method to produce glucosamine from N-acetylglucosamine.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: February 19, 2008
    Assignee: Arkion Life Sciences LLC
    Inventors: Ming-De Deng, J. David Angerer, Don Cyron, Alan D. Grund, Thomas A. Jerrell, Jr., Candice Leanna, Owen Mathre, Reinhardt Rosson, Jeff Running, Dave Severson, Linsheng Song, Sarah Wassink
  • Patent number: 7083809
    Abstract: Disclosed is a composition comprising a substantially purified Cytokine Inhibitory Factor (CIF) having certain characteristics, including the ability to inhibit RNA transcription of the pro-inflammatory cytokines tumor necrosis factor alpha (TNF-?), interleukin-1-beta (IL-1?), and interleukin-2 (IL-2). Also disclosed is a method for substantially purifying the Cytokine Inhibitory Factor and a method for modulating the immune system of an animal using such composition.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: August 1, 2006
    Assignee: Arkion Life Sciences, LLC
    Inventors: Subramanian Iyer, William L. Johnson, Lance Nguyen, Steven C. Ross, Ruye Xing
  • Publication number: 20060094085
    Abstract: The present invention relates to a method and materials for producing glucosamine by fermentation of a genetically modified microorganism. Included in the present invention are genetically modified microorganisms useful in the present method for producing glucsamine, as well as recombinant nucleic acid molecules and the proteins produces by such recombinant nucleic acid molecules.
    Type: Application
    Filed: October 5, 2005
    Publication date: May 4, 2006
    Applicant: Arkion Life Sciences LLC d/b/a Bio-Technical Resources
    Inventors: Alan Berry, Richard Burlingame, James Millis
  • Publication number: 20040110257
    Abstract: The invention provides a biological method of producing farnesol or geranylgeraniol.
    Type: Application
    Filed: November 20, 2003
    Publication date: June 10, 2004
    Applicant: Arkion Life Sciences LLC.
    Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
  • Patent number: 6743440
    Abstract: A composition, preferably used to reduce methane formation in a ruminant, wherein the composition is a combination of a polycyclic quinone compound and an ionophore compound.
    Type: Grant
    Filed: October 10, 2000
    Date of Patent: June 1, 2004
    Assignee: Arkion Life Sciences LLC
    Inventor: Kenneth E. Ballinger, Jr.
  • Patent number: 6743609
    Abstract: The present invention provides an isolated linoleate isomerase and its nucleic acid and amino acid sequence. The present invention also provides a method for producing CLA from an oil using an immobilized bacterial cell or an isolated linoleate isomerase.
    Type: Grant
    Filed: December 23, 1998
    Date of Patent: June 1, 2004
    Assignee: Arkion Life Sciences LLC
    Inventors: Reinhardt A. Rosson, Alan D. Grund, Ming-De Deng, Fernando Sanchez-Riera
  • Patent number: 6729265
    Abstract: A method for supplementing new antibody or adding additional titer of an already present antibody into the circulating system in a newborn by feeding antibody to the newborn within the first few days of its life. The antibody is preferably obtained from the egg of an immunized mother and fed to the newborn within the first 24 hours of its life.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: May 4, 2004
    Assignee: Arkion Life Sciences LLC
    Inventors: Leslie A. Confer, Jeffrey G. Hunchar, Kevin C. Somerville
  • Patent number: 6706267
    Abstract: The invention is directed to a composition and method for the treatment and prevention of inflammation and inflammatory related disorders. The composition is glucosamine in combination with an egg product. It is generally preferred that the egg product is obtained from an avian which has been hyperimmunized with an immungenic mixture and/or which contains an anti-inflammatory composition.
    Type: Grant
    Filed: September 7, 2000
    Date of Patent: March 16, 2004
    Assignee: Arkion Life Sciences LLC
    Inventors: Orn Adalsteinsson, Jeffrey G. Hunchar, Subramanian Iyer