Patents Assigned to Arkion Life Sciences LLC
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Publication number: 20130217098Abstract: A recombinant yeast that makes an isoprenoid compound is provided. The yeast comprises an endogenous mevalonate pathway comprising (i) an enzyme that converts acetyl-CoA to acetoacetyl-CoA, (ii) an enzyme that converts acetoacetyl-CoA to hydroxymethylglutaryl-CoA, (iii) an enzyme that converts hydroxymethylglutaryl-CoA to mevalonic acid, (iv) an enzyme that converts mevalonic acid to phosphomevalonic acid, (v) an enzyme that converts phosphomevalonic acid to phosphomevalonate, and (vi) an enzyme that converts phosphomevalonate to isopentenyl pyrophosphate. The yeast further comprises heterologous nucleic acid sequences encoding an enzyme that converts hydroxymethylglutaryl-CoA to mevalonic acid, an enzyme that converts mevalonic acid to phosphomevalonic acid, an enzyme that converts phosphomevalonic acid to phosphomevalonate, and an enzyme that converts phosphomevalonate to isopentenyl pyrophosphate.Type: ApplicationFiled: April 17, 2013Publication date: August 22, 2013Applicant: Arkion Life Sciences, LLCInventor: Arkion Life Sciences, LLC
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Patent number: 8241888Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: May 24, 2007Date of Patent: August 14, 2012Assignee: Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Publication number: 20110195470Abstract: The invention provides a biological method of producing isoprenoids.Type: ApplicationFiled: April 18, 2011Publication date: August 11, 2011Applicant: ARKION LIFE SCIENCES, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7927861Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: November 9, 2010Date of Patent: April 19, 2011Assignee: Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7927862Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: November 9, 2010Date of Patent: April 19, 2011Assignee: Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7910560Abstract: A method for increasing breast meat yield in avians by treating the poultry with an effective amount of natamycin. The effective amount of natamycin can be added to the avian's feed wither directly or in the form of a premix containing a carrier.Type: GrantFiled: May 4, 2004Date of Patent: March 22, 2011Assignee: Arkion Life Sciences LLCInventor: A. Franklin Carter
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Patent number: 7842497Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: May 24, 2007Date of Patent: November 30, 2010Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7838279Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: May 24, 2007Date of Patent: November 23, 2010Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7732161Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: May 24, 2007Date of Patent: June 8, 2010Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7718417Abstract: The invention provides a biological method of producing isoprenoids.Type: GrantFiled: May 24, 2007Date of Patent: May 18, 2010Assignee: Bio-Technical Resources, a division of Arkion Life Sciences, LLCInventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 7488493Abstract: A performance aid for increasing the effectiveness of a bioactive agent, and a composition including both the performance and the bioactive agent. The performance aid increases the effectiveness of the bioactive agent by providing a composition that adheres well to a surface but also increases transferability of the bioactive agent to a target animal that contacts the treated surface.Type: GrantFiled: April 23, 2004Date of Patent: February 10, 2009Assignee: Arkion Life Sciences, LLCInventors: Kenneth E. Ballinger, Jr., Michele Santer
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Publication number: 20090017520Abstract: The present invention relates to a method and materials for producing glucosamine by fermentation of a genetically modified microorganism. Included in the present invention are genetically modified microorganisms useful in the present method for producing glucosamine, as well as recombinant nucleic acid molecules and the proteins produces by such recombinant nucleic acid molecules.Type: ApplicationFiled: June 22, 2007Publication date: January 15, 2009Applicant: Arkion Life Sciences LLC d/b/a Bio-Technical ResourcesInventors: Alan Berry, Richard P. Burlingame, James R. Millis
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Patent number: 7332304Abstract: A biosynthetic method for producing glucosamine and N-acetylglucosamine is disclosed. Such a method includes the fermentation of a genetically modified microorganism to produce glucosamine and/or N-acetylglucosamine. Also disclosed are genetically modified microorganisms that are useful for producing glucosamine and N-acetylglucosamine. In addition, methods of recovering N-acetylglucosamine that has been produced by a fermentation process, including methods that result in N-acetylglucosamine of high purity, are described. Also disclosed is a method to produce glucosamine from N-acetylglucosamine.Type: GrantFiled: July 1, 2003Date of Patent: February 19, 2008Assignee: Arkion Life Sciences LLCInventors: Ming-De Deng, J. David Angerer, Don Cyron, Alan D. Grund, Thomas A. Jerrell, Jr., Candice Leanna, Owen Mathre, Reinhardt Rosson, Jeff Running, Dave Severson, Linsheng Song, Sarah Wassink
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Patent number: 7083809Abstract: Disclosed is a composition comprising a substantially purified Cytokine Inhibitory Factor (CIF) having certain characteristics, including the ability to inhibit RNA transcription of the pro-inflammatory cytokines tumor necrosis factor alpha (TNF-?), interleukin-1-beta (IL-1?), and interleukin-2 (IL-2). Also disclosed is a method for substantially purifying the Cytokine Inhibitory Factor and a method for modulating the immune system of an animal using such composition.Type: GrantFiled: February 11, 2003Date of Patent: August 1, 2006Assignee: Arkion Life Sciences, LLCInventors: Subramanian Iyer, William L. Johnson, Lance Nguyen, Steven C. Ross, Ruye Xing
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Publication number: 20060094085Abstract: The present invention relates to a method and materials for producing glucosamine by fermentation of a genetically modified microorganism. Included in the present invention are genetically modified microorganisms useful in the present method for producing glucsamine, as well as recombinant nucleic acid molecules and the proteins produces by such recombinant nucleic acid molecules.Type: ApplicationFiled: October 5, 2005Publication date: May 4, 2006Applicant: Arkion Life Sciences LLC d/b/a Bio-Technical ResourcesInventors: Alan Berry, Richard Burlingame, James Millis
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Publication number: 20040110257Abstract: The invention provides a biological method of producing farnesol or geranylgeraniol.Type: ApplicationFiled: November 20, 2003Publication date: June 10, 2004Applicant: Arkion Life Sciences LLC.Inventors: James R. Millis, Julie Maurina-Brunker, Thomas W. McMullin
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Patent number: 6743440Abstract: A composition, preferably used to reduce methane formation in a ruminant, wherein the composition is a combination of a polycyclic quinone compound and an ionophore compound.Type: GrantFiled: October 10, 2000Date of Patent: June 1, 2004Assignee: Arkion Life Sciences LLCInventor: Kenneth E. Ballinger, Jr.
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Patent number: 6743609Abstract: The present invention provides an isolated linoleate isomerase and its nucleic acid and amino acid sequence. The present invention also provides a method for producing CLA from an oil using an immobilized bacterial cell or an isolated linoleate isomerase.Type: GrantFiled: December 23, 1998Date of Patent: June 1, 2004Assignee: Arkion Life Sciences LLCInventors: Reinhardt A. Rosson, Alan D. Grund, Ming-De Deng, Fernando Sanchez-Riera
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Patent number: 6729265Abstract: A method for supplementing new antibody or adding additional titer of an already present antibody into the circulating system in a newborn by feeding antibody to the newborn within the first few days of its life. The antibody is preferably obtained from the egg of an immunized mother and fed to the newborn within the first 24 hours of its life.Type: GrantFiled: June 27, 2002Date of Patent: May 4, 2004Assignee: Arkion Life Sciences LLCInventors: Leslie A. Confer, Jeffrey G. Hunchar, Kevin C. Somerville
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Patent number: 6706267Abstract: The invention is directed to a composition and method for the treatment and prevention of inflammation and inflammatory related disorders. The composition is glucosamine in combination with an egg product. It is generally preferred that the egg product is obtained from an avian which has been hyperimmunized with an immungenic mixture and/or which contains an anti-inflammatory composition.Type: GrantFiled: September 7, 2000Date of Patent: March 16, 2004Assignee: Arkion Life Sciences LLCInventors: Orn Adalsteinsson, Jeffrey G. Hunchar, Subramanian Iyer