Patents Assigned to (ARO) (VOLCANI CENTER)
  • Patent number: 12098362
    Abstract: A method of killing a phytopathogen or reducing growth thereof is provided. The method comprising exposing the phytopathogen to an effective amount of a composition comprising a biologically pure culture of Daldinia sp. or at least one volatile organic compound (VOC) being produced by the biologically pure culture and capable of killing the phytopathogen or reducing growth thereof.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: September 24, 2024
    Assignee: THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER)
    Inventors: David Ezra, Orna Liarzi
  • Patent number: 12071646
    Abstract: Isolated mogroside and mogrol biosynthetic pathway enzyme polypeptides useful in mogroside biosynthesis are provided. Mogroside biosynthetic pathway enzymes of the invention include squalene epoxidase (SE), epoxy hydratase (EH), cytochrome p450 (Cyp), cucurbitadienol synthase (CDS) and udp-glucosyl-transferase (UGT), Also provided are methods of producing a mogroside using the isolated mogroside and mogrol biosynthetic enzyme polypeptides, the methods comprising contacting a mogrol and/or a glycosylated mogrol (mogroside) with at least one UDP glucose glucosyl transferase (UGT) enzyme polypeptide of the invention catalyzing glucosylation of the mogrol and/or the glucosylated mogrol to produce a mogroside with an additional glucosyl moietie(s), thereby producing the mogroside.
    Type: Grant
    Filed: December 28, 2021
    Date of Patent: August 27, 2024
    Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
    Inventors: Maxim Itkin, Rachel Davidovich-Rikanati, Shahar Cohen, Vitaly Portnoy, Adi Doron-Faigenboim, Marina Petreikov, Shmuel Shen, Yaakov Tadmor, Yosef Burger, Efraim Lewinsohn, Nurit Katzir, Arthur A. Schaffer, Elad Oren
  • Patent number: 12063902
    Abstract: Methods of in vitro clonal propagation and regeneration in Cannabis are provided. Also provided is the use of such methods in improvements of cannabis cultivars such as via breeding.
    Type: Grant
    Filed: July 11, 2022
    Date of Patent: August 20, 2024
    Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
    Inventors: Moshe Arie Flaishman, Reut Cohen Peer, Oded Cohen, Samuel Bocobza
  • Patent number: 12048295
    Abstract: A system for monitoring individual food intake of a livestock animal includes a calibration system configured to measure weight or volume of food intake of an animal over a pre-defined period of time and to calibrate a mathematical model for the animal based on the measure, a tracking system configured track animal eating behavior at times other than the pre-defined period of time and a computing system. The pre-defined period of time is less than three weeks. The mathematical model relates eating behavior of the animal and defined physiological parameters of the animal with food intake. The computing system determines food intake of the animal over a lactation period based on the mathematical model for the animal as calibrated and the eating behavior at the times other than the pre-defined period of time.
    Type: Grant
    Filed: November 22, 2018
    Date of Patent: July 30, 2024
    Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
    Inventors: Ilan Halachmi, Victor Bloch, Harel Levit, Ehud Ram
  • Patent number: 12016353
    Abstract: A method of feeding an aquaculture of an aquatic animal species of interest is provided. The method comprising providing the aquaculture with an aquaculture feed comprising a sub-optimal dose of protein and an effective amount of butyric acid or salt thereof, the effective amount facilitating reducing feed conversion ratio (FCR). Also provided are feed compositions for aquaculturing.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: June 25, 2024
    Assignees: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center), Israel Oceanographic and Limnological Research, Ltd. (PBC)
    Inventors: Amir Bitan, William Koven, Amos Tandler, Guy Allon
  • Patent number: 11998008
    Abstract: Disclosed herein are agricultural biocontrol compounds and compositions comprising the compounds, and methods of using the same. Specifically, nematacide fungicidal and herbecidial compounds, compositions comprising thereof, and methods for preventing and inhibiting nematodes, fungi and weed growth are disclosed herein.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: June 4, 2024
    Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (VOLCANI CENTER)
    Inventors: David Ezra, Orna Liarzi, Ariel Ewenson
  • Patent number: 11992014
    Abstract: Disclosed are beneficial complexes comprising entomopathogenic nematodes (EPNs), binders, and external cargos, methods for preparing the same and systems comprising the same.
    Type: Grant
    Filed: April 14, 2019
    Date of Patent: May 28, 2024
    Assignee: THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER)
    Inventors: Itamar Glazer, Liora Salame, Dana Ment, Neta Morag
  • Patent number: 11951138
    Abstract: A method of mimicking a phenotype of a first ruminating animal in a second ruminating animal is disclosed. The method comprises administering to the second ruminating animal a microbial composition comprising a plurality of microbes having a signature which is statistically significantly similar to the microbial signature of a rumen microbiome of the first ruminating animal, wherein the first and the second ruminating animal are of identical species, thereby mimicking the phenotype of the first ruminating animal in the second ruminating animal.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: April 9, 2024
    Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
    Inventors: Itzhak Mizrahi, Elie Jami
  • Patent number: 11939620
    Abstract: A method of determining the feed efficiency and methane production of a ruminating animal comprising analyzing the number and/or diversity of a bacterial taxon of a microbiome of the animal or of a gene content of said microbiome, wherein a number and/or diversity of said taxon below a predetermined level is indicative of an animal having a high feed efficiency and low methane production, or a number of genes below a predetermined level is indicative of an animal having a high feed efficiency and low methane production.
    Type: Grant
    Filed: February 9, 2021
    Date of Patent: March 26, 2024
    Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
    Inventor: Itzhak Mizrahi
  • Patent number: 11839195
    Abstract: A tomato plant exhibiting a facultative parthenocarpy is provided. The plant comprises a loss-of-function mutation in a SlAGL6 gene and alternatively or additionally characterized by an average fruit weight/plant at least about the same as that of a non-parthenocarpic tomato of the same genetic background under fertilization permissive conditions of the non-parthenocarpic tomato. Also provided are methods of producing such plants and processed products produced from same.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: December 12, 2023
    Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
    Inventors: Rivka Barg, Yehiam Salts, Chen Klap, Itzhak Arazi, Ester Yeshayahou, Anthony Bolger, Sara Shabtai
  • Patent number: 11827892
    Abstract: A polynucleotide comprising a nucleic acid sequence encoding an expression product of interest under a transcriptional control of a heterologous cis-acting regulatory element comprising a nucleic acid sequence at least 85% identical to SEQ ID NO: 2 (CsUbiquitin10), 4 (CsPs2), 6 (CsActin), 8 (CsTubulin), 10 (Cs EIF), 28 (metallothionein 2A), 30 (Catalase), 32 (Asparagine synthetase), 34 (60S ribosomal protein L3), 38 (40S ribosomal protein S3a), 40 (Phi-1 protein) or 44 (Receptor for activated protein kinase C) is provided. Also provided are nucleic acid constructs and cells comprising same.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: November 28, 2023
    Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
    Inventors: Moshe Arie Flaishman, Reut Cohen Peer, Oded Cohen, Samuel Bocobza
  • Patent number: 11812746
    Abstract: A method of controlling a fungus infection in a plant susceptible to Botrytis infection is provided. The method comprising applying to the plant an effective amount of a phenylalanine or an analog thereof for controlling said fungus infection in the plant.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: November 14, 2023
    Assignee: THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER)
    Inventors: Michal Oren-Shamir, Moran Oliva, Efraim Lewinsohn, Noam Alkan, Yigal Elad
  • Patent number: 11573173
    Abstract: Apparatus and method for detecting a dissolved gaseous impurity in an aqueous environment, comprises a tube for isolating liquid surface, or a sampler for obtaining a liquid sample from the aqueous environment, a vacuum pump located to exert a vacuum, leaving the surface to evaporate into the vacuum; and a holding compartment for holding evaporated gas which may then be analyzed using electrochemical or spectroscopic methods. The apparatus is useful for detecting levels of ammonia in fish ponds or indeed any impurity that may be dissolved in the water.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: February 7, 2023
    Assignees: Ariel Scientific Innovations Ltd., The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center), The State of Israel, Ministry of Agriculture & Rural Development
    Inventors: Amir Abramovich, Nafttaly Goldshleger, Sheenan Harpaz, Aharon Greenberg, Alexander Shulzinger
  • Patent number: 11331301
    Abstract: A method of treating a malignant disease in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of a first liquid chromatography fraction of a cannabis extract comprising at least 75% tetrahydrocannabinolic acid (THCA), and a therapeutically effective amount of a second liquid chromatography fraction of a cannabis extract comprising at least 75% cannabigerolic acid (CBGA), wherein the first liquid chromatography fraction comprises cannabis derived active ingredients other than the THCA, and the second liquid chromatography fraction comprises cannabis derived active ingredients other than the CBGA, thereby treating the malignant disease in the subject.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: May 17, 2022
    Assignees: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center), Mor Research Applications Ltd.
    Inventors: Hinanit Koltai, Yoram Kapulnik, Dvora Namdar, Moran Mazuz, Ido Laish, Timna Naftali
  • Patent number: 11297868
    Abstract: A method of preparing a bacterial composition is disclosed. The method comprises: (a) in vitro co-culturing beneficial bacteria with biofilm-producing bacteria in a growth substrate under conditions that generate a biofilm which comprises the beneficial bacteria and the non-pathogenic bacteria; and (b) isolating the biofilm from the growth substrate.
    Type: Grant
    Filed: May 29, 2017
    Date of Patent: April 12, 2022
    Assignees: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center), Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Moshe Shemesh, Ram Reifen
  • Publication number: 20210337753
    Abstract: Methods of in vitro clonal propagation, regeneration and transformation in Cannabis are provided. Also provided is the use of such methods in improvements of cannabis cultivars such as via breeding.
    Type: Application
    Filed: June 6, 2019
    Publication date: November 4, 2021
    Applicants: (ARO) (VOLCANI CENTER)
    Inventors: Moshe Arie FLAISHMAN, Reut COHEN PEER, Oded COHEN, Samuel BOCOBZA
  • Patent number: 10993981
    Abstract: A composition for the treatment of follicular tonsillitis is provided. The composition includes a therapeutically effective amount of carnosic acid and a carrier consisting of pharmaceutically acceptable solvents and ingredients. The composition is in the form of spray and includes ethanol and polyoxyethylenesorbitan monooleate and at least 0.1% oregano essential oil. Other compositions and treatment methods are disclosed.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: May 4, 2021
    Assignee: THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIATION (ARO), (VOLCANI CENTER)
    Inventors: Yoseph Rakover, Nativ Dudai
  • Patent number: 10975385
    Abstract: A method of regulating plant stomata conductance is provided. The method comprises modulating in the plant the level and/or activity of a type B hexokinase in a guard cell specific manner, thereby regulating plant conductance.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: April 13, 2021
    Assignees: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center), Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: David Granot, Gilor Kelly, Menachem Moshelion
  • Patent number: 10961559
    Abstract: A method of determining the feed efficiency and methane production of a ruminating animal comprising analyzing the number and/or diversity of a bacterial taxon of a microbiome of the animal or of a gene content of said microbiome, wherein a number and/or diversity of said taxon below a predetermined level is indicative of an animal having a high feed efficiency and low methane production, or a number of genes below a predetermined level is indicative of an animal having a high feed efficiency and low methane production.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: March 30, 2021
    Assignee: The State of Israel Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
    Inventor: Itzhak Mizrahi
  • Patent number: 10767187
    Abstract: A method of producing trilobatin is disclosed. The method comprising contacting a polypeptide comprising an amino acid sequence at least 90% identical to SEQ ID NO: 8 and having a 4?-O-glycosyltransferase activity with phloretin and UDP-glucose under conditions which allow the formation of trilobatin, thereby producing trilobatin. A method of producing a plant which produces trilobatin, transgenic plant or plant cell and methods of producing transgenic plants are disclosed. Composition comprising trilobatin are also disclosed.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: September 8, 2020
    Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
    Inventor: Mwafaq Ibdah