Patents Assigned to Aron S.A.
  • Benzamidine derivatives
    Patent number: 4246272
    Abstract: The invention relates to a compound selected from the group consisting of compounds of the formula: ##STR1## in which R.sub.1, R.sub.2 and R.sub.3 are independently selected from hydrogen, halogen, trifluoromethyl, nitro, C.sub.1-4 alkoxy and C.sub.1-4 alkyl,R.sub.4 represents a heterocyclic radical selected from the radicals having the formulae ##STR2## in which R.sub.5 and R.sub.6 are independently selected from hydrogen, C.sub.1-4 alkyl, phenyl and halophenyl,R.sub.7 is selected from hydrogen and C.sub.1-4 alkyl, and a pharmaceutically acceptable acid addition salt thereof. These compounds are useful for the treatment of gastric ulcers.
    Type: Grant
    Filed: July 5, 1978
    Date of Patent: January 20, 1981
    Assignee: Aron S.A.
    Inventor: Michel Noel
  • Amino derivatives of pyrazolo [1,5-a]s-triazine, and their therapeutic applications
    Patent number: 4183930
    Abstract: This invention relates to compounds having the general formula: ##STR1## in which: R.sub.1 represents a hydrogen atom or a (C.sub.1-4) alkyl radical,R.sub.2 represents a hydrogen atom, a (C.sub.1-4) alkyl radical, a (C.sub.2-4) alkenyl radical, a (C.sub.1-4) alkoxy-(C.sub.1-4) alkyl radical or a tetrahydrofuryl- or tetrahydropyranyl-(C.sub.1-4) alkyl radical,R.sub.3 represents a hydrogen atom or a (C.sub.1-4) alkyl radical, andR.sub.4 represents a hydrogen atom or a (C.sub.1-4) alkyl radical, and their pharmaceutically acceptable acid addition salts.Said compounds have valuable bronchodilator properties.
    Type: Grant
    Filed: December 19, 1978
    Date of Patent: January 15, 1980
    Assignee: Aron S.A.
    Inventor: Claude Cohen
  • (3-Piperazinocarbonylimino-quanidino)-isoxazoles
    Patent number: 4103010
    Abstract: The present invention relates to compounds having the general formula: ##STR1## in which R.sub.1 and R.sub.2, which may be the same or different, represent each a hydrogen atom, a C.sub.1 -C.sub.6 alkyl radical or a C.sub.3 -C.sub.6 cycloalkyl radical; R.sub.3 represents a hydrogen atom or a C.sub.1 -C.sub.4 alkyl radical; R.sub.4 and R.sub.5, which may be the same or different, represent a hydrogen atom, a C.sub.1 -C.sub.6 alkyl radical or, together with the nitrogen atom to which they are attached, form a pyrrolidino, piperidino, morpholino or piperazinyl radical optionally substituted with a C.sub.1 -C.sub.4 alkyl radical, or a 4-hydroxypiperidino radical, and their pharmaceutically acceptable acid addition salts.Said compounds are therapeutically useful for the control of the cardio-vascular system and of the blood pressure.
    Type: Grant
    Filed: September 20, 1977
    Date of Patent: July 25, 1978
    Assignee: Aron S.A.R.L.
    Inventor: Jean-Jacques Sterne