Patents Assigned to AROS Applied Biotechnology ApS
  • Gene expression in biological conditions
    Patent number: 7666586
    Abstract: The present invention relates to a method of determining the presence or absence of a biological condition in animal tissue, wherein the expression of genes in normal tissue and tissue from the biological condition is examined and correlated to standards. The invention further relates to the treatment of the biological condition and an assay for determining the condition. More particularly the invention concerns gene expression in epithelial tissue, such as urianry bladder under both normal and abnormal conditions.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: February 23, 2010
    Assignee: Aros Applied Biotechnology APS
    Inventors: Torben F. Ørntoft, Thomas Thykjaer, Karin Demtröder
  • Classification of cancer
    Publication number: 20090297506
    Abstract: The invention discloses a method for classification of cancer in an individual having contracted cancer. The method of classification involves the determination of microsatellite status and a prognostic marker by examining gene expression patterns. The invention also relates to various methods of treatment of cancer. Additionally, the present invention concerns a pharmaceutical composition for treatment of cancer and uses of the present invention. The invention also relates to an assay for classification of cancer.
    Type: Application
    Filed: December 23, 2004
    Publication date: December 3, 2009
    Applicant: Aros Applied Biotechnology ApS
    Inventors: Torben Falck Orntoft, Paivi Laiho, Lauri A. Aaltonen, Mogens Kruhoffer, Jens Ledet Jensen
  • Gene expression in biological conditions
    Publication number: 20060240426
    Abstract: The present invention relates to a method of predicting the prognosis of a biological condition in animal tissue, wherein the expression of genes is examined and correlated to standards. The invention further relates to the treatment of the biological condition and. an assay for predicting the prognosis. In particular, the invention concerns gene expression in epithelial tissue, such as urinary bladder under both normal and abnormal conditions.
    Type: Application
    Filed: November 3, 2003
    Publication date: October 26, 2006
    Applicant: Aros Applied Biotechnology ApS
    Inventors: Torben Orntoft, Thomas Andersen, Lars Andersen, Jens Jensen
  • Gene expression in bladder tumors
    Patent number: 6936417
    Abstract: Methods for analyzing tumor cells, particularly bladder tumor cells employ gene expression analysis of samples. Gene expression patterns are formed and compared to reference patterns. Alternatively gene expression patterns are manipulated to exclude genes which are expressed in contaminating cell populations. Another alternative employs subtraction of the expression of genes which are expressed in contaminating cell types. These methods provide improved accuracy as well as alternative basis for analysis from diagnostic and prognostic tools currently available.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: August 30, 2005
    Assignee: AROS Applied Biotechnology ApS
    Inventor: Torben F. Orntoft