Patents Assigned to ARRAY BIOPHARM, INC.
  • Quinazoline analogs as receptor Tyrosine Kinase inhibitors
    Publication number: 20080194558
    Abstract: This invention concerns quinazoline analogs of Formula I: where an A group is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to three independent R3 groups. The invention also includes methods of using these compounds as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
    Type: Application
    Filed: April 21, 2008
    Publication date: August 14, 2008
    Applicant: ARRAY BIOPHARM, INC.
    Inventors: Eli Wallace, George Topalov, Joseph Lyssikatos, Alexandre Buckmelter, Qian Zhao