Abstract: Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. Formula (I).
Type:
Application
Filed:
January 9, 2009
Publication date:
October 13, 2011
Applicants:
Genentech, Inc., Array BoPharma Inc.
Inventors:
Anna Banka, Josef R. Bencsik, James Blake, Martin Hentermann, Stephen T. Schlachter, Eli M. Wallace, Rui Xu