Patents Assigned to ARRESTO BIOSCIENCES
  • LOX AND LOXL2 INHIBITORS AND USES THEREOF
    Publication number: 20090053224
    Abstract: The present application relates to anti-LOX and anti-LOXL2 antibodies and their use in purification, diagnostic and therapeutic methods. Antibodies include monoclonal antibodies, humanized antibodies and functional fragments thereof. Anti-LOX and anti-LOXL2 antibodies can be used to identify and treat conditions such as a fibrotic condition, angiogenesis, or to prevent a transition from an epithelial cell state to a mesenchymal cell state.
    Type: Application
    Filed: August 1, 2008
    Publication date: February 26, 2009
    Applicant: ARRESTO BIOSCIENCES
    Inventors: Victoria Smith, Scott Ogg, Peter Van Vlasselaer, Vivian E. Barry, Derek Marshall, Alison Kay Holzer, Hector Rodriguez, Miho Oyasu, Scott Alan McCauley, Carlos Aurelio Garcia, Donna Hiroko Tokuoka Biermann