Patents Assigned to Artemis Pharmaceuticals GmbH
  • SHRNA AND SIRNA EXPRESSION IN A LIVING ORGANISM UNDER CONTROL OF A CODON-OPTIMIZED REPRESSOR GENE
    Publication number: 20090210955
    Abstract: The present invention relates to a biological entity carrying a regulator construct comprising a specific repressor gene and a responder construct comprising at least one segment corresponding to a short hairpin RNA (shRNA) or corresponding to complementary short interfering RNA (siRNA) strands, said at least one segment being under control of a promoter which contains an operator sequence corresponding to the repressor. The invention further relates to a method for preparing said biological entity and its use.
    Type: Application
    Filed: June 8, 2006
    Publication date: August 20, 2009
    Applicant: ARTEMIS PHARMACEUTICALS GMBH
    Inventors: Jost Seibler, Frieder Schwenk, Birgit Küter-Luks
  • SHRNA AND SIRNA AND MIRNA EXPRESSION IN A LIVING ORGANISM UNDER CONTROL OF A CODON-OPTIMIZED REPRESSOR GENE
    Publication number: 20090025097
    Abstract: The present invention relates to a biological entity, notably a rat, carrying a regulator construct comprising a specific repressor gene and a responder construct comprising at least one segment corresponding to a short hairpin RNA (shRNA) or corresponding to complementary short interfering RNA (siRNA) strands or corresponding to miRNA, said at least one segment being under control of a promoter which contains an operator sequence corresponding to the repressor. The invention further relates to a method for preparing said biological entity and its use.
    Type: Application
    Filed: May 9, 2008
    Publication date: January 22, 2009
    Applicant: ARTEMIS PHARMACEUTICALS GMBH
    Inventors: Jost SEIBLER, Frieder SCHWENK, Birgit KUTER-LUKS, Michael BADER, Katarina KOTNIK
  • Sirna mediated gene silencing in transgenic animals
    Publication number: 20060218654
    Abstract: The present invention relates to a process that enables constitutive and inducible gene knock down in living organisms using a short hairpin RNA expression vector integrated into the genome of the organism.
    Type: Application
    Filed: October 10, 2003
    Publication date: September 28, 2006
    Applicant: Artemis Pharmaceuticals GmbH
    Inventors: Jost Seibler, Frieder Schwenk, Ralf Kühn, Birgit Küter-Luks
  • Targeted transgenesis using the rosa26 locus
    Publication number: 20060205077
    Abstract: The invention provides a method for targeted transgenesis using the Rosa26 locus. Suitable nucleotide acid sequences and vectors for the targeted transgenesis and recombinase mediated transgenesis are provided. The Rosa26 locus proved to be a suitable integration site allowing strong and predictable expression of inserted transgenes carrying exogenous promoters.
    Type: Application
    Filed: January 8, 2004
    Publication date: September 14, 2006
    Applicant: Artemis Pharmaceuticals GmbH
    Inventors: Frieder Schwenk, Jost Seibler, Nicole Faust, Ralf Kuhn
  • Automated gene-targeting using non-toxic detectable markers
    Publication number: 20060179502
    Abstract: The invention relates to a method that enables automated identification and isolation of cells harbouring a predetermined genetic modification (homologous recombination) using detectable/sortable markers, e.g. fluorescence markers, to identify homologous DNA modifications. Suitable vectors are also provided.
    Type: Application
    Filed: February 3, 2004
    Publication date: August 10, 2006
    Applicant: ARTEMIS PHARMACEUTICALS GMBH
    Inventors: Gunther Kauselmann, Branko Zevnik, Jost Seibler, Heidrun Kern
  • Method for cryoconservation of Zebrafish sperm
    Patent number: 6465169
    Abstract: A method for cryoconservation of Zebrafish sperm, and Zebrafish sperm obtained by said method.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: October 15, 2002
    Assignee: Artemis Pharmaceuticals GmbH
    Inventors: Brigitte Walderich, Renate Nordin