Abstract: The invention provides, among other things, methods and compositions for expanding stem cells. The invention further provides methods, devices and systems for directing differentiation of expanded stem cells. The invention further provides methods, devices and systems for treating a subject with differentiated cells in a subject in need thereof.
Type:
Application
Filed:
December 6, 2013
Publication date:
July 10, 2014
Applicant:
ARTERIOCYTE INC.
Inventors:
Yukang Zhao, Stephen Fischer, Anirudhasingh Sodha
Abstract: The invention provides, among other things, methods and systems for expanding CD133+ cells. The invention further provides methods and systems for increasing the blood flow to an ischemic tissue in a subject in need thereof, such as to ischemic myocardium. The invention further provides methods and systems for directing differentiation of expanded CD133+ cells. The invention further provides methods and systems for treating a subject with differentiated cells in a subject in need thereof.
Type:
Grant
Filed:
January 9, 2009
Date of Patent:
March 11, 2014
Assignees:
Arteriocyte Inc., Universite Pierre ET Marie Curie (Paris VI)
Inventors:
Ramasamy Sakthivel, Donald J. Brown, Hai-Quan Mao, Luc Douay, Vincent J. Pompili, Kevin McIntosh, Hiranmoy Das, Yukang Zhao
Abstract: The invention provides, in part, methods for treating liver disease in a subject in need thereof. The invention further provides methods for improving liver function in a subject in need thereof, such as a subject with an ischemic liver or a cirrhotic liver. In some aspects, the methods of treatment comprise the administration of AC133+ alone or in combination with other cell populations.
Type:
Application
Filed:
November 15, 2007
Publication date:
October 2, 2008
Applicant:
Arteriocyte Inc.
Inventors:
Ramasamy Sakthivel, Donald J. Brown, Vincent Pompili, Yukang Zhao
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