Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.

Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.

Abstract: A syringe includes a syringe cylinder and a distal end designed as a syringe cone. The distal end comprises a region set back in a radial direction such that an edge extending in the circumferential direction is formed. The edge has a first chamfer, and comprises an attachment piece having a clamping region. Holding forces are introduced from the attachment piece via the clamping region in the region of the syringe set back in a radial direction. The clamping region comprises a distal edge. The the distal edge of the clamping region has a second chamfer.

Abstract: The invention proposes a device (1) for controlling the temperature of products to be frozen during a freeze drying process. This device (1) is characterized in that at least one Peltier element (3) is present.

Abstract: A syringe or carpule includes a cylinder that surrounds a cavity and comprises an end that has an access to the cavity, membrane seals the access and has a puncture area that can be punctured by a needle. A two-part cap has a predetermined breaking line and spans the membrane. A cover device covers the puncture area of the membrane in a sterile manner and comprises a sealing area spanning the puncture area. The sealing area covers the puncture area in a sterile manner regardless of axial forces to be applied in the area of the predetermined breaking line.

Abstract: A device for controlling the temperature of products to be frozen during a freeze drying process includes a plurality of Peltier elements and at least one magazine including different areas for accommodating products to be frozen. The Peltier elements are separably controllable such that the different areas of the magazine are maintainable at different temperatures during a freeze drying process.

Abstract: A coating device for coating an inside of a hollow body with an atomized fluid has at least one atomizing tube enclosing an atomizing channel. A pressurized propellant gas for atomizing an unatomized fluid can be introduced into the atomizing tube. The atomizing tube has at least one outlet opening and further has at least one hollow needle having a discharge opening for the unatomized fluid. The at least one hollow needle interacts with the atomizing channel and is arranged essentially coaxially thereto. The atomizing tube and the hollow needle form a Venturi arrangement.

Abstract: A piston for a medical hollow body such as a syringe or a carpule includes at least one sliding surface for contact with the hollow body. The piston has at least one receiving area in which a lubricant can be received, and at least one dispensing mechanism for dispensing the at least one lubricant from the at least one receiving area to the at least one sliding surface.

Abstract: A coating device for coating an inside of a hollow body with an atomized fluid has at least one atomizing tube enclosing an atomizing channel. A pressurized propellant gas for atomizing an unatomized fluid can be introduced into the atomizing tube. The atomizing tube has at least one outlet opening and further has at least one hollow needle having a discharge opening for the unatomized fluid. The at least one hollow needle interacts with the atomizing channel and is arranged essentially coaxially thereto. The atomizing tube and the hollow needle form a Venturi arrangement.

Abstract: A device (1) for assembly of a pharmaceutical application aid (51), particularly a pen, is proposed. The device (1) is characterized by a holding device (3) for fixation of a first housing sleeve (5) that accommodates a pharmaceutical container, particularly a carpule (23), and by a stop (43) for limiting a displacement of a second housing sleeve (35) relative to the first housing sleeve (5).

Abstract: A coating device for coating an inside of a hollow body with an atomized fluid has at least one atomizing tube enclosing an atomizing channel. A pressurized propellant gas for atomizing an unatomized fluid can be introduced into the atomizing tube. The atomizing tube has at least one outlet opening and further has at least one hollow needle having a discharge opening for the unatomized fluid. The at least one hollow needle interacts with the atomizing channel and is arranged essentially coaxially thereto. The atomizing tube and the hollow needle form a Venturi arrangement.

Abstract: A device (1) for assembly of a pharmaceutical application aid (51), particularly a pen, is proposed. The device (1) is characterized by a holding device (3) for fixation of a first housing sleeve (5) that accommodates a pharmaceutical container, particularly a carpule (23), and by a stop (43) for limiting a displacement of a second housing sleeve (35) relative to the first housing sleeve (5).

Abstract: A container for medical products has at least one chamber. At least two lyophilized active substances and/or auxiliary substances are jointly present in the at least one chamber.

Abstract: A device places a plug and simultaneously checks a correct position alignment of the plug with a holding element for fixing a hollow body. The device has at least one first and one second opening and a plug placement mechanism with which the plug is be inserted into the second opening of the hollow body. The device has a measuring head that is traversed by at least one channel. The channel can be fluidically connected to the first opening of the hollow body. The device can further include a pressure sensor which can be fluidically connected to the channel of the measuring head.

Abstract: A method for filling dual-chamber systems (3) in pre-sterilizable carrier systems (1) is proposed, which comprises the following steps: provision of at least one washed, siliconized and sterilized dual-chamber system (3) with respectively one separating element separating the two chambers (5, 5?) from one another in a magazine (9), which accommodates the at least one dual-chamber system (3), wherein the magazine (9) is arranged in a container (11) sealed with a closure element (13); feeding the container (11) into a clean room; opening the container (11) and filling a first chamber (5) of the at least one dual-chamber system (3); closing the first chamber (5) with a gas-permeable closure element (19); freeze drying the solution (L1) contained in the first chamber (5); closing the first chamber (5) with a closure element (19); filling a second chamber (5?) of the at least one dual-chamber system (3); closing the second chamber (5?); discharge from the clean room.

Abstract: A pre-sterilizable carrier system includes providing at least one washed and sterilized dual-chamber system in a magazine. The dual-chamber system includes a separating element separating first and second chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element.

Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.

Abstract: A device for large-scale lyophilization of pharmaceutical solutions in medical hollow bodies, includes a lyophilization device and at least one camera. Images of at least one pharmaceutical solution to be lyophilized are recorded by the at least one camera. The images may be used for controlling and/or monitoring the lyophilization process.

Abstract: A device for checking the seal-tightness of closure caps on medical hollow bodies has a drive, a retaining element for the hollow body, and a retaining device for the closure cap. The retaining device is pivotably supported relative to the retaining element. The device further includes a sensor for the relative rotation of the retaining device with respect to the retaining element. A torque may be applied to the closure cap by the drive, the retaining element, and the retaining device. A hollow body and a closure cap are gripped by the retaining device and the retaining element from the same side, as viewed along the longitudinal axis of a hollow body.

Abstract: The invention relates to an attachment for a syringe or cartridge having a cannula, wherein the attachment comprises a sealing element, which is molded onto the cannula.