Abstract: The present disclosure provides compositions, systems, and tools for modeling the canine liver and methods of using the same. The disclosure provides micropatterned hepatocyte co-cultures where individual cell populations remain functionally stable during long-term culture.
Type:
Grant
Filed:
January 26, 2016
Date of Patent:
June 30, 2020
Assignee:
Ascendance Biotechnology, Inc.
Inventors:
John K. McGeehan, Stacy Krzyzewski, Michael McVay