Patents Assigned to Asimov, Inc.
  • STABLE PRODUCTION SYSTEMS FOR AAV VECTOR PRODUCTION
    Publication number: 20250011811
    Abstract: Described herein are AAV vector production systems and HSV-helper systems. Also described herein are engineered cells and kits comprising an AAV vector production system and/or an HSV-helper system and methods of using the same for AAV vector production.
    Type: Application
    Filed: November 9, 2022
    Publication date: January 9, 2025
    Applicant: ASIMOV INC.
    Inventors: Christopher S. Stach, Alec A.K. Nielsen
  • INTEGRASES, LANDING PAD ARCHITECTURES, AND ENGINEERED CELLS COMPRISING THE SAME
    Publication number: 20240409906
    Abstract: Described herein are modified bacteriophage serine integrases that function in mammalian cells. Also described herein are landing pad architectures. Engineered cells comprising these integrases and landing pads are also described, which facilitate site-specific genomic integration of pay load molecules.
    Type: Application
    Filed: October 13, 2022
    Publication date: December 12, 2024
    Applicant: Asimov Inc.
    Inventors: Michael T. Leonard, Jeremy J. Gam, Christopher S. Stach, Alec A.K. Nielsen
  • VIRAL VECTOR PRODUCTION SYSTEMS, ENGINEERED CELLS FOR VIRAL VECTOR PRODUCTION, AND METHODS OF USE THEREOF
    Publication number: 20240254513
    Abstract: Described herein are viral vector production systems and engineered cells for viral vector production. Also described herein are methods of using the engineered cells to produce viral vectors.
    Type: Application
    Filed: May 17, 2022
    Publication date: August 1, 2024
    Applicant: Asimov Inc.
    Inventors: Jeremy J. Gam, Christopher S. Stach, Alec A.K. Nielsen
  • COMPOSITIONS AND METHODS FOR ADENO-ASSOCIATED VIRAL PRODUCTION
    Publication number: 20240247283
    Abstract: Disclosed herein are cell genetically engineered cell for AAV production. The genetically engineered cell comprises molecular systems for temporal control of expression of genes required for AAV production. Also disclosed herein are methods of using genetically engineered cells for AAV production.
    Type: Application
    Filed: May 6, 2022
    Publication date: July 25, 2024
    Applicant: Asimov Inc.
    Inventors: Jeremy J. Gam, Brianna E.K. Jayanthi, Michael T. Leonard, Alec A.K. Nielsen
  • STABLE PRODUCTION SYSTEMS FOR LENTIVIRAL VECTOR PRODUCTION
    Publication number: 20240191253
    Abstract: Described herein are lentiviral vector production systems. Also described herein are engineered cells and kits comprising a lentiviral vector production system and methods of using the same for lentiviral vector production.
    Type: Application
    Filed: April 22, 2022
    Publication date: June 13, 2024
    Applicant: Asimov Inc.
    Inventors: Jeremy J. Gam, Alec A.K. Nielsen
  • COMPOSITIONS OF POLYNUCLEIC ACID VECTORS AND USES THEREOF
    Publication number: 20220090091
    Abstract: Disclosed herein are compositions of destination and entry vectors. Also disclosed herein are the use of destination and entry vectors in methylation-obstructed assembly reactions, wherein the assembled sequences may be used as entry vectors in subsequent assembly reactions.
    Type: Application
    Filed: January 7, 2020
    Publication date: March 24, 2022
    Applicant: Asimov, Inc.
    Inventors: Alec A.K. Nielsen, Yekaterina Tarasova, Amber Marie Delhagen
  • UNIVERSAL CHIMERIC RECEPTORS
    Publication number: 20210317181
    Abstract: Disclosed herein are chimeric receptors and precursors, chimeric antigen receptors and precursors, universal chimeric receptor cell precursors, chimeric antigen receptor T cells, and methods of constructing and using the same.
    Type: Application
    Filed: August 2, 2019
    Publication date: October 14, 2021
    Applicant: Asimov, Inc.
    Inventor: Alec Andrew Nielsen