Patents Assigned to Aslan Pharmaceuticals Pte. Ltd.
  • Cancer therapy
    Patent number: 11382903
    Abstract: A method of treating haematological cancer with a therapy comprising a DHODH inhibitor. Also provided is a combination therapy comprising a pan-HER inhibitor and a DHODH inhibitor for treating a haematological cancer.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: July 12, 2022
    Assignee: Aslan Pharmaceuticals Pte. Ltd.
    Inventors: Bertil Lindmark, Ann Gee Lisa Ooi, Mark Thomas McHale
  • Cancer therapy
    Patent number: 11311548
    Abstract: A method of treating haematological cancer with a therapy comprising a DHODH inhibitor. Also provided is a combination therapy comprising a pan-HER inhibitor and a DHODH inhibitor for treating a haematological cancer.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: April 26, 2022
    Assignee: Aslan Pharmaceuticals Pte. Ltd.
    Inventors: Bertil Lindmark, Ann Gee Lisa Ooi, Mark Thomas McHale
  • Combination therapy comprising Varlitinib and an anticancer agent
    Patent number: 10849899
    Abstract: In one aspect the present disclosure provides a method of sensitizing a cancer patient to chemotherapy by administering a combination therapy comprising; a) a therapeutically effective amount of a compound of formula (I) an enantiomer thereof or a pharmaceutically acceptable salts of any one of the same, and b) a chemotherapeutic agent or a combination of chemotherapeutic agents.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: December 1, 2020
    Assignee: ASLAN Pharmaceuticals PTE LTD
    Inventors: Bertil Lindmark, Lisa Ooi
  • Varlitinib for use in the treatment of resistant or refractory cancer
    Patent number: 10682353
    Abstract: The present disclosure provides a method of treating a patient with refractory or resistant cancer by administering a therapeutically effective amount of a compound of formula (I), such as Varlitinib, or an enantiomer thereof or a pharmaceutically acceptable salt of any one of the same. Also provided is a compound of formula (I) for use in the treatment of resistant or refractory cancer and use of a compound of formula (I) for the manufacture of a medicament for the treatment of resistant or refractory cancer.
    Type: Grant
    Filed: September 5, 2016
    Date of Patent: June 16, 2020
    Assignee: ASLAN Pharmaceuticals PTE LTD
    Inventors: Bertil Lindmark, Lisa Ooi
  • Maintenance Therapy for the Treatment of Cancer
    Publication number: 20190321365
    Abstract: The present disclosure relates to a maintenance therapy for prolongation of remission of a cancer comprising administering a therapeutically effective amount of a compound of formula (I) an enantiomer thereof or pharmaceutically acceptable salt of any one of the same or a pharmaceutical composition thereof.
    Type: Application
    Filed: June 30, 2017
    Publication date: October 24, 2019
    Applicant: Aslan Pharmaceuticals Pte. Ltd.
    Inventor: Bertil Lindmark
  • Combination therapy comprising varlitinib and an anticancer agent
    Patent number: 10357494
    Abstract: In one aspect the present disclosure provides a method of sensitizing a cancer patient to chemotherapy by administering a combination therapy comprising; a) a therapeutically effective amount of a compound of formula (I) an enantiomer thereof or a pharmaceutically acceptable salts of any one of the same, and b) a chemotherapeutic agent or a combination of chemotherapeutic agents.
    Type: Grant
    Filed: September 5, 2016
    Date of Patent: July 23, 2019
    Assignee: ASLAN Pharmaceuticals PTE LTD
    Inventors: Bertil Lindmark, Lisa Ooi
  • CANCER THERAPY
    Publication number: 20190151326
    Abstract: A method of treating haematological cancer with a therapy comprising a DHODH inhibitor. Also provided is a combination therapy comprising a pan-HER inhibitor and a DHODH inhibitor for treating a haematological cancer.
    Type: Application
    Filed: January 18, 2019
    Publication date: May 23, 2019
    Applicant: Aslan Pharmaceuticals Pte. Ltd.
    Inventors: Bertil Lindmark, Ann Gee Lisa Ooi
  • Method of Treating Liver Cancer
    Publication number: 20190134034
    Abstract: A method of treating liver cancer, such as hepatocellular carcinoma, by administering a compound of formula (I), such as Varlitinib, or an enantiomer thereof, or a pharmaceutically acceptable salt thereof. Also provided is a compound of formula (I) for use in the treatment of liver cancer and use of a compound of formula (I) in the manufacture of a medicament for the treatment of liver cancer.
    Type: Application
    Filed: April 21, 2017
    Publication date: May 9, 2019
    Applicant: ASLAN Pharmaceuticals Pte. Ltd.
    Inventors: Lisa Ooi, Bertil Lindmark
  • Treatment of Biliary Duct Cancer
    Publication number: 20190117655
    Abstract: The present disclosure provides a method of treating a biliary duct cancer, such as cholangiocarcinoma, by administering a therapeutically effective amount of a compound of formula (I), in particular Varlitinib, an enantiomer thereof or a pharmaceutically acceptable salt of any one of the same.
    Type: Application
    Filed: September 18, 2018
    Publication date: April 25, 2019
    Applicant: ASLAN Pharmaceuticals PTE LTD
    Inventors: Bertil Lindmark, Mark Thomas McHale, Lisa Ooi
  • CANCER THERAPY
    Publication number: 20190038610
    Abstract: A method of treating haematological cancer with a therapy comprising a DHODH inhibitor. Also provided is a combination therapy comprising a pan-HER inhibitor and a DHODH inhibitor for treating a haematological cancer.
    Type: Application
    Filed: October 8, 2018
    Publication date: February 7, 2019
    Applicant: Aslan Pharmaceuticals Pte. Ltd.
    Inventors: Bertil Lindmark, Ann Gee Lisa Ooi