Abstract: The present invention provides compositions and methods having improved specificity and sensitivity for the pre-operative assessment of ovarian tumors (e.g., symptomatic and asymptomatic adnexal mass) in a variety of subjects (e.g., pre- and post-menopausal women) having a variety of ovarian cancer types (e.g., low malignant potential, intermediate malignant potential, high malignant potential).
Abstract: The present invention provides compositions and methods that provide a high degree of sensitivity and a high degree of specificity for the non-invasive assessment of endometriosis in women having a variety of endometriosis types (e.g., endometriosis, endometriotic cysts, endometrioma, or another benign condition of the endometrium) and at a variety of disease states (e.g., early and late stage).
Type:
Application
Filed:
February 18, 2021
Publication date:
March 23, 2023
Applicant:
Aspira Women's Health Inc.
Inventors:
Nitin BHARDWAJ, Todd PAPPAS, Herbert FRITSCHE
Abstract: The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.
Type:
Application
Filed:
December 17, 2021
Publication date:
October 6, 2022
Applicants:
Aspira Women's Health Inc., The Johns Hopkins University
Inventors:
Zhen ZHANG, Daniel W. CHAN, Eric T. FUNG, Zheng WANG, Fujun ZHANG
Abstract: The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.
Type:
Grant
Filed:
November 10, 2017
Date of Patent:
February 22, 2022
Assignees:
Aspira Women's Health Inc., The Johns Hopkins University
Inventors:
Zhen Zhang, Daniel W. Chan, Eric T. Fung, Zheng Wang, Fujun Zhang
Abstract: The present invention provides compositions and methods that provide a high degree of sensitivity and a high degree of specificity for the preoperative assessment of ovarian tumors in an African American subject (e.g., pre- and post-menopausal women) having a variety of ovarian cancer types (e.g., clear cell/mucinous, low malignant potential, high malignant potential) and at a variety of disease states (e.g., early and late stage).
Type:
Application
Filed:
August 13, 2019
Publication date:
July 15, 2021
Applicant:
Aspira Women's Health Inc.
Inventors:
Charles Dunton, Rowan Bullock, Herbert Fritsche
Abstract: The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
Type:
Application
Filed:
December 14, 2020
Publication date:
June 17, 2021
Applicants:
ASPIRA WOMEN'S HEALTH INC., THE JOHNS HOPKINS UNIVERSITY
Inventors:
ERIC THOMAS FUNG, ENRIQUE DALMASSO, VLADIMIR PODUST, ZHENG WANG, Zhen Zhang