Abstract: Stents and methods for producing stents are provided. The stent includes a polymeric substrate comprised of 10-50% (w/w) of alginate and 45-85% (w/w) of gelatine and further includes a polymeric biodegradable resin for coating said polymeric substrate. The stent can also include a contrast agent. The stent can further include a crosslinking agent. The method for producing the stent includes dissolving the alginate and gelatine in water and stirring to obtain a polymeric substrate. The method also includes adding a crosslinking agent to the substrate, injecting the substrate into a mold to obtain the stent, placing the stent in a first alcohol solution, and placing the stent in a crosslinking agent solution. The method further includes placing the stent in a second alcohol solution, and a series of interchanging drying and immersing steps.
Type:
Grant
Filed:
May 17, 2016
Date of Patent:
May 11, 2021
Assignee:
ASSOCIATION FOR THE ADVANCEMENT OF TISSUE ENGINEER
Inventors:
Rui Luis Gonçalves Dos Reis, Ana Rita Cruz Duarte, Alexandre António Antunes Barros, Estêvão Augusto Rodrigues De Lima, Carlos André Ribeiro Oliveira, Jorge Manuel Nunes Correia Pinto