Patents Assigned to ASSOICATION INSTITUT DE MYOLOGIE
  • Allele-specific silencing therapy for dynamin 2-related diseases
    Patent number: 11926829
    Abstract: The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases caused by heterozygous mutation and/or overexpression of Dynamin 2.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: March 12, 2024
    Assignees: ASSOICATION INSTITUT DE MYOLOGIE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Marc Bitoun, Delphine Trochet, Bernard Prudhon