Abstract: Compounds of formula (I), or salts thereof, which inhibit acetyl CoA (acetyl coenzyme A):diacylglycerol acyltransferase (DGAT1) activity are provided, wherein R1, R2 and R3 are each independently selected from hydrogen, fluoro, chloro, cyano, trifluoromethyl, trifluoromethoxy and difluoromethoxy; together with processes for their preparation, pharmaceutical compositions containing them and their use as medicaments.
Type:
Grant
Filed:
May 29, 2007
Date of Patent:
December 27, 2011
Assignee:
AsstraZeneca AB
Inventors:
Roger John Butlin, Alleyn Thomas Plowright