Patents Assigned to AstŕaZeneca AB
  • Amidinobenzylamine derivatives and their use as thrombin inhibitors
    Patent number: 6599894
    Abstract: There is provided compounds of formula I wherein R1, R2, Y, R3 and R4 have meanings given in the description which are useful as, or as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: July 29, 2003
    Assignee: AstŕaZeneca AB
    Inventors: Tord Inghardt, Jan-Erik Nyström