Abstract: Ifosfamide having improved properties is obtained by crystallization from a solvent mixture selected from the group consisting of (a) a mixture of diethyl ether and a C.sub.1 -C.sub.3 alkanol or (b) a mixture of diisopropyl ether and a C.sub.1 -C.sub.3 alkanol under specific controlled conditions.
Type:
Grant
Filed:
March 3, 1988
Date of Patent:
November 21, 1989
Assignee:
Asta Pharma Akteingesellschaft
Inventors:
Jurgen Engel, Siegfried Muller, Werner Laubner