Patents Assigned to ASTI Corporation
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Patent number: 11433680Abstract: Disclosed is a liquid-sealed cartridge that includes: a liquid storage portion configured to store liquid; a flow path in which the liquid stored in the liquid storage portion flows; and a liquid sealing portion configured to seal the liquid in the liquid storage portion, in which the liquid sealing portion has an outer circumferential portion and a center-side low strength portion disposed closer to a center than the outer circumferential portion, and the center-side low strength portion is broken when pressed, to allow the liquid in the liquid storage portion to flow in the flow path.Type: GrantFiled: September 25, 2020Date of Patent: September 6, 2022Assignees: SYSMEX CORPORATION, ASTI CORPORATIONInventors: Kazuyoshi Horii, Shun Nakamoto, Noriyuki Ogai, Yasuhiro Toda, Kimiaki Iwahori
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Patent number: 11344710Abstract: The purpose of the present invention is to provide a microneedle array and a microneedle manufacturing method, which improves medical solution delivery efficiency and facilitates manufacturing. The microneedle array is provided with a first divisional element, a second divisional element to be bonded to the first divisional element, a longitudinal passage formed between the first divisional element and the second divisional element bonded to each other; and a horizontal hole, having an orifice on a lateral side and formed in a direction parallel to a bonding surface of the first divisional element with the second divisional element, and communicating to the longitudinal passage.Type: GrantFiled: March 29, 2018Date of Patent: May 31, 2022Assignee: ASTI CORPORATIONInventors: Noriyuki Ogai, Masahiro Takigawa
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Patent number: 11117135Abstract: Disclosed is a liquid-sealed cartridge in which a liquid is transferred by a centrifugal force generated when the liquid-sealed cartridge is rotated around a rotation shaft, including: a liquid storage portion configured to store the liquid therein; a seal having an outer peripheral portion connected to the liquid storage portion, the seal being configured to seal the liquid storage portion; a flow path connected to the liquid storage portion via the seal, through which the liquid in the liquid storage portion is transferred by the centrifugal force in a direction away from the rotation shaft, wherein, when the seal receives a pressing force, the seal is inclined in a pressing direction, with one portion of the outer peripheral portion thereof remaining connected with the liquid storage portion, and the other portion of the outer peripheral portion being separated from the liquid storage portion.Type: GrantFiled: October 27, 2017Date of Patent: September 14, 2021Assignees: Sysmex Corporation, ASTI CorporationInventors: Kazuyoshi Horii, Takao Fujiwara, Tomoyuki Nose, Yasunori Maekawa, Noriyuki Ogai, Yasuhiro Toda
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Publication number: 20210178087Abstract: The purpose of the present invention is to provide an injection needle and an injection device which are capable of adjusting the puncture depth of a needle. The present invention is equipped with: a needle; a needle base holding the needle such that the needle protrudes from the distal end side; and an adjuster provided on the outer periphery of the needle base so as to be movable in the axial direction of the needle base. By adjusting the axial-direction position of the adjuster, the protrusion length of the needle can be adjusted. Consequently, the puncture depth of the needle can be adjusted, and there is no need to prepare a plurality of type of injection needles having different protrusion lengths.Type: ApplicationFiled: April 18, 2019Publication date: June 17, 2021Applicant: ASTI CorporationInventors: Akinori INOH, Isamu NONAKA, Noriyuki OGAI
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Patent number: 10744311Abstract: The purpose of the present invention is to provide a micro-needle unit and an injection device capable of being readily connected to a liquid supply source and capable of performing an effective injection via a simple configuration. The micro-needle unit is provided with a plurality of micro-needles disposed on the puncturing side and provided with a flow channel, and drug solution supply needles disposed on the side opposite from the puncturing side in a number less than that of the micro-needles and provided with a flow channel in communication with the aforementioned flow channel, the micro-needle unit thereby being capable of being readily connected to a liquid supply source and capable of performing an effective injection via a simple configuration.Type: GrantFiled: January 28, 2015Date of Patent: August 18, 2020Assignee: ASTI CORPORATIONInventors: Kenpei Onozuka, Noriyuki Ogai
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Patent number: 10697989Abstract: This liquid-sealed cartridge includes: a cartridge body including a plurality of liquid storage portions; a seal body configured to seal an opening of each of the plurality of liquid storage portions; and an elastic body disposed so as to be opposed to the plurality of liquid storage portions, the elastic body being configured to form a passage adjacent to the plurality of liquid storage portions. Each of the plurality of liquid storage portions and the passage are configured to be communicated with each other by the corresponding seal body being pushed to be opened through the elastic body.Type: GrantFiled: October 27, 2017Date of Patent: June 30, 2020Assignees: SYSMEX CORPORATION, ASTI CORPORATIONInventors: Kazuyoshi Horii, Takao Fujiwara, Noriyuki Ogai, Kenpei Onozuka, Yasuhiro Toda
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Patent number: 10500386Abstract: The purpose of the present invention is to provide: a microneedle array that does not readily break during puncture and thereby improves the reliability of puncturing, the microneedle array being capable of administering the desired amount of the target substance; and a microneedle manufacturing method for manufacturing a microneedle array of such description. To achieve the above purpose, the invention is characterized in being provided with: a substrate; a plurality of microneedle base sections formed integrally in a protruding manner on the substrate; and microneedle end sections installed at the ends of the microneedle base sections to form microneedles and provided with in vivo solubility or biodegradability, the microneedle end sections holding the target substance, a recess for admitting the microneedle end sections being provided to the microneedle base sections, and a part of the microneedle end sections being admitted into the recess for admitting the microneedle end sections.Type: GrantFiled: July 29, 2014Date of Patent: December 10, 2019Assignees: ASTI CORPORATION, TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Takuya Tamaru, Noriyuki Ogai, Akifumi Inoue, Sigeru Tomita, Ikuhiko Wada
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Patent number: 10441767Abstract: The invention relates to a jig for microneedle array placement that is provided with a main jig body with through holes through which the microneedles of the microneedle array will pass and a guiding part that guides the microneedle array to be incorporated into the main jig body and leads the microneedles into the through holes, and a microneedle array device using the jig for microneedle array placement. The invention prevents the deformation of the skin surface during puncture and allows penetration of the microneedles to the prescribed depth under the skin.Type: GrantFiled: October 27, 2011Date of Patent: October 15, 2019Assignee: ASTI CORPORATIONInventors: Takuya Tamaru, Isamu Nonaka, Yuko Wada
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Patent number: 9931496Abstract: A microneedle array includes a microneedle unit that includes microneedles; and a microneedle unit support member that includes an opening, guides both ends of the microneedle unit through inclined grooves, and arranges tips of the microneedles so as to project through the opening in an inclined manner.Type: GrantFiled: May 2, 2013Date of Patent: April 3, 2018Assignee: ASTI CORPORATIONInventors: Takuya Tamaru, Noriyuki Ogai, Ryo Sugimura, Isamu Nonaka, Yuko Wada
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Publication number: 20160082239Abstract: The objective of the present invention is to provide: a microneedle array which is capable of inserting a microneedle into the skin at an oblique angle and thereby, upon injection with the microneedle, is capable of both relieving the patient's pain and preventing a drug solution from leaking; and a microneedle array device which comprises the microneedle array. To this end, a microneedle array comprises: a microneedle unit that includes microneedles; and a microneedle unit support member that includes an opening, guides both ends of the microneedle unit through inclined grooves, and arranges tips of the microneedles so as to project through the opening in an inclined manner.Type: ApplicationFiled: May 2, 2013Publication date: March 24, 2016Applicant: ASTI CorporationInventors: Takuya TAMARU, Noriyuki OGAI, Ryo SUGIMURA, Isamu NONAKA, Yuko WADA
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Publication number: 20130218084Abstract: The invention relates to a jig for microneedle array placement that is provided with a main jig body with through holes through which the microneedles of the microneedle array will pass and a guiding part that guides the microneedle array to be incorporated into the main jig body and leads the microneedles into the through holes, and a microneedle array device using the jig for microneedle array placement. The invention prevents the deformation of the skin surface during puncture and allows penetration of the microneedles to the prescribed depth under the skin.Type: ApplicationFiled: October 27, 2011Publication date: August 22, 2013Applicant: ASTI CorporationInventors: Takuya Tamaru, Isamu Nonaka, Yuko Wada
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Patent number: 7229540Abstract: To provide a biochip, a biochip manufacturing method, an electrophoresis method, and an electrophoresis apparatus, by which the detection accuracy may improve, there is a biochip introducing a sample in band form into a sample separation passage, by a means for reducing the band width of sample, at which the sample is before being introduced in the sample separation passage in band form. The band of sample supplied to the sample separation passage is compressed, and the expansion by diffusion may be prevented, thus the detection accuracy may improve.Type: GrantFiled: January 7, 2003Date of Patent: June 12, 2007Assignees: President of Shizuoka University, a Japanese Government Agency, ASTI CorporationInventors: Naomichi Okamoto, Noriyuki Okumiya, Ryo Sugimura
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Publication number: 20040084311Abstract: To provide a biochip, a biochip manufacturing method, an electrophoresis method, and an electrophoresis apparatus, by which the detection accuracy may improve, there is a biochip introducing a sample in band form into a sample separation passage, by a means for reducing the band width of sample, at which the sample is before being introduced in the sample separation passage in band form. The band of sample supplied to the sample separation passage is compressed, and the expansion by diffusion may be prevented, thus the detection accuracy may improve.Type: ApplicationFiled: January 7, 2003Publication date: May 6, 2004Applicants: President of Shizuoka University, A Japanese Government Agency, ASTI CorporationInventors: Naomichi Okamoto, Noriyuki Okumiya, Ryo Sugimura
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Patent number: 5528421Abstract: A signal mirror includes an irradiation device for reflecting incident light by a same reflection function as a plane mirror and irradiating reflected light to an irradiation target; and an optical axis finding device including a sheet having at least a surface on an irradiation device side as a retroreflection face, for reflecting incident light incident on the sheet from the irradiation device side in an opposite direction to the irradiation target using retroreflection and reflection by the irradiation device, thereby ensuring finding of an optical axis of reflected light irradiated on the irradiation target by the irradiation device. The reflected light can be irradiated on the irradiation target by the irradiation device while the optical axis of the reflected light is found by the optical axis finding device.Type: GrantFiled: March 9, 1995Date of Patent: June 18, 1996Assignee: ASTI CorporationInventor: Hajime Kashibuchi
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Patent number: D868246Type: GrantFiled: January 26, 2018Date of Patent: November 26, 2019Assignee: ASTI CORPORATIONInventors: Noriyuki Ogai, Masahiro Takigawa
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Patent number: D882070Type: GrantFiled: March 26, 2019Date of Patent: April 21, 2020Assignee: ASTI CORPORATIONInventors: Akinori Inoh, Isamu Nonaka