Abstract: A method of treating or preventing a respiratory infection can include delivering aerosolized droplets of an antiviral solution to lung tissue of a subject, the antiviral solution including an aqueous carrier and an ATH conjugate that is solubilized in the aqueous carrier. The ATH conjugate includes antithrombin covalently bonded to heparin, the heparin including a polysaccharide chain having from about 15 to about 1,500 monosaccharide units.
Type:
Application
Filed:
March 25, 2022
Publication date:
June 6, 2024
Applicant:
ATH Therapeutics Inc.
Inventors:
Leslie Roy BERRY, Anthony Kam Chuen CHAN, William JACKSON, Attilio DIFIORE
Abstract: Medical devices, systems, and methods for treating conditions using antithrombin-heparin conjugates are disclosed. For example, medical devices can be coated with antithrombin-heparin (ATH) resulting in reduced thrombogenicity. Various conditions can likewise be treated with ATH.
Type:
Grant
Filed:
June 10, 2016
Date of Patent:
September 12, 2023
Assignee:
ATH Therapeutics Inc.
Inventors:
Attilio Difiore, Leslie Roy Berry, Anthony Kam Chuen Chan