Abstract: The subject invention relates to methods for detection of mutations in a PKD gene using DHPLC. The invention includes the following aspects: identification of PKD unique sites; design of PKD-specific primers; amplification of PKD-specific products; and analysis of PCR amplified products by DHPLC. The invention further relates to compositions such as identified unique sites and PKD-specific primers, and kits for performing the methods of the invention.
Type:
Application
Filed:
February 26, 2002
Publication date:
August 14, 2003
Applicant:
Athena Diagnostics
Inventors:
Jeffrey George Jones, Aidan Noel Hennigan, John A. Curran, Susan Kimberly Allen, Normand J. Robichaud, Jing Wang, Kerry Ellen Flynn, Jorge A. Garces, Christopher M. Palatucci