Abstract: The present invention provides a method for preventing and treating gastrointestinal diseases such as dyspepsia, irritable bowel disease and chemotherapy-associated nausea by administering an antagonist or partial agonist of 5HT1a receptors.
Type:
Grant
Filed:
October 13, 2000
Date of Patent:
August 29, 2006
Assignee:
Athpharma Limited
Inventors:
Timothy G. Dinan, Patrick W. N. Keeling
Abstract: Isosorbide mononitrate formulations and methods of treatment are disclosed. The formulations and treatments provide for subtherapeutic levels of the mononitrate in a washout period to prevent nitrate tolerance.
Type:
Application
Filed:
April 23, 2003
Publication date:
May 13, 2004
Applicant:
Athpharma Limited
Inventors:
Edward James Geoghegan, Seamus Mulligan, Mary Margaret Foynes
Abstract: Isosorbide mononitrate formulations and methods of treatment are disclosed. The formulations and treatments provide for subtherapeutic levels of the mononitrate in a washout period to prevent nitrate tolerance.
Type:
Grant
Filed:
February 7, 1997
Date of Patent:
November 4, 2003
Assignee:
Athpharma Limited
Inventors:
Edward James Geoghegan, Seamus Mulligan, Mary Margaret Foynes