Patents Assigned to ATIR Holding S.A.
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Patent number: 11033549Abstract: Disclosed herein are compounds for use in lightening skin, treating uneven skin pigmentation and/or improving the appearance of aging skin, as well as methods utilizing the compounds, and anti-aging compositions comprising the compounds and a pharmaceutically acceptable carrier. The compounds have the general Formula I: or a pharmaceutically acceptable salt thereof, wherein the dashed line, X, Y, Z, Ra-Rd, and R1-R3 are as defined herein.Type: GrantFiled: March 14, 2018Date of Patent: June 15, 2021Assignee: ATIR Holding S.A.Inventors: Izabella Munblit, Karina Tsipe
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Publication number: 20200085826Abstract: Disclosed herein are compounds for use in lightening skin, treating uneven skin pigmentation and/or improving the appearance of aging skin, as well as methods utilizing the compounds, and anti-aging compositions comprising the compounds and a pharmaceutically acceptable carrier. The compounds have the general Formula I: or a pharmaceutically acceptable salt thereof, wherein the dashed line, X, Y, Z, Ra-Rd, and R1-R3 are as defined herein.Type: ApplicationFiled: March 14, 2018Publication date: March 19, 2020Applicant: ATIR Holding S.A.Inventors: Izabella MUNBLIT, Karina TSIPE
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Publication number: 20200069549Abstract: Compositions are disclosed herein, as well as methods and uses utilizing the compositions for improving the appearance of aging skin, lightening skin, treating uneven skin pigmentation and/or treating a sexual disorder. The compositions comprise a compound of the general Formula I: or a pharmaceutically acceptable salt thereof, wherein the dashed line, X, Y, Z, Ra-Rd, and R1-R5 are as defined herein, and a carrier suitable for topical administration on skin, being in a form of a water-in-oil emulsion, the emulsion comprising: propylene glycol, phosphatidyl choline, lauroyl macrogolglycerides, macrogolglycerol stearate, ethanol, caprylocaproyl macrogolglycerides, propylene glycol monolaurate and water, in proportions described herein.Type: ApplicationFiled: March 14, 2018Publication date: March 5, 2020Applicant: ATIR Holding S.A.Inventors: Leonid LURYA, Izabella MUNBLIT, Karina TSIPE
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Patent number: 9353067Abstract: Biologically active compounds, which are useful for treating a sexual disorder, are provided herein. Further provided are pharmaceutical compositions formulated for transdermal composition, which comprise a biologically active compound useful for treating a sexual disorder. The compounds and pharmaceutical compositions allow for a prolonged presence of a biologically active compound in plasma. Further provided herein are methods and uses of the compounds and pharmaceutical compositions described herein in the treatment of a sexual disorder, including female sexual disorders.Type: GrantFiled: December 26, 2011Date of Patent: May 31, 2016Assignee: ATIR Holding S.A.Inventor: Leonid Lurya
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Patent number: 9278957Abstract: Novel piperazine, piperidine and tetrahydropyridine derivatives comprising a dibenzofurane moiety are provided herein, as well as pharmaceutical compositions comprising same and therapeutic uses thereof.Type: GrantFiled: December 15, 2014Date of Patent: March 8, 2016Assignee: ATIR Holding S.A.Inventors: Vladimir Kogan, Lev Tabachnik
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Patent number: 9034872Abstract: Novel heterocyclic compounds having the Formula I: wherein A, B, D, E, G, K, L, M, Q, T, X, Y and Z are as defined herein, which exhibit a dopamine receptor (preferably a D4 receptor) agonistic activity, and/or a PDE5 inhibitory activity, processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of sexual disorders such as decreased libido, orgasm disorder and erectile dysfunction are disclosed.Type: GrantFiled: December 17, 2013Date of Patent: May 19, 2015Assignee: ATIR Holding S.A.Inventors: Dmitry Tworowski, Ron Matsievitch, Vladimir Kogan
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Patent number: 8912196Abstract: Novel piperazine, piperidine and tetrahydropyridine derivatives comprising a dibenzofurane moiety are provided herein, as well as pharmaceutical compositions comprising same and therapeutic uses thereof.Type: GrantFiled: May 26, 2010Date of Patent: December 16, 2014Assignee: ATIR Holding S.A.Inventors: Vladimir Kogan, Lev Tabachnik
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Patent number: 8614319Abstract: Novel heterocyclic compounds having the Formula I: wherein A, B, D, E, G, K, L, M, Q, T, X, Y and Z are as defined herein, which exhibit a dopamine receptor (preferably a D4 receptor) agonistic activity, and/or a PDE5 inhibitory activity, processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of sexual disorders such as decreased libido, orgasm disorder and erectile dysfunction are disclosed.Type: GrantFiled: November 13, 2012Date of Patent: December 24, 2013Assignee: ATIR Holding S.A.Inventors: Dmitry Tworowski, Ron Matsievitch, Vladimir Kogan
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Publication number: 20130072479Abstract: Novel heterocyclic compounds, which exhibit a dopamine receptor (preferably a D4 receptor) agonistic activity, and/or a PDE5 inhibitory activity, processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of sexual disorders such as decreased libido, orgasm disorder and erectile dysfunction are disclosed.Type: ApplicationFiled: November 13, 2012Publication date: March 21, 2013Applicant: ATIR Holding S.A.Inventor: ATIR Holding S.A.
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Patent number: 8349850Abstract: Novel heterocyclic compounds having the formula: or a pharmaceutically acceptable salt thereof, wherein A, B, D, E, G, K, L, M, Q, T, X, Y and Z are as described in the specification, which exhibit a dopamine receptor (preferably a D4 receptor) agonistic activity, and/or a PDE5 inhibitory activity, are disclosed, as well as processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of sexual disorders such as decreased libido, orgasm disorder and erectile dysfunction.Type: GrantFiled: March 28, 2007Date of Patent: January 8, 2013Assignee: ATIR Holding S.A.Inventors: Dmitry Tworowski, Ron Matsievitch, Vladimir Kogan
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Patent number: 8168639Abstract: Novel heterocyclic compounds of formula I: A-B-D??Formula I or a pharmaceutically acceptable salt thereof, wherein: A is selected from the group consisting of a moiety having general Formula II and a moiety having general Formula III: B is a moiety selected from the group consisting of: D is a moiety selected from the group consisting of: ?which exhibit a dopamine receptor (preferably a D4 receptor) and/or a serotonine receptor (preferably 5HTA1 agonistic activity), processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of medical conditions associated with the dopaminergic and/or serotonergic systems (e.g., sexual disorders, dyskinesia, anxiety) are disclosed.Type: GrantFiled: September 24, 2007Date of Patent: May 1, 2012Assignee: ATIR Holding S.A.Inventor: Vladimir Kogan
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Publication number: 20100216807Abstract: Novel heterocyclic compounds of formula I: A-B-D??Formula I or a pharmaceutically acceptable salt thereof, wherein: A is selected from the group consisting of a moiety having general Formula II and a moiety having general Formula III: B is a moiety selected from the group consisting of: D is a moiety selected from the group consisting of: which exhibit a dopamine receptor (preferably a D4 receptor) and/or a serotonine receptor (preferably 5HTA1 agonistic activity), processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of medical conditions associated with the dopaminergic and/or serotonergic systems (e.g., sexual disorders, dyskinesia, anxiety) are disclosed.Type: ApplicationFiled: September 24, 2007Publication date: August 26, 2010Applicant: ATIR Holding S.AInventor: Vladimir Kogan
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Publication number: 20100029671Abstract: Novel heterocyclic compounds, which exhibit a dopamine receptor (preferably a D4 receptor) agonistic activity, and/or a PDE5 inhibitory activity, processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of sexual disorders such as decreased libido, orgasm disorder and erectile dysfunction are disclosed.Type: ApplicationFiled: March 28, 2007Publication date: February 4, 2010Applicant: ATIR HOLDING S.A.Inventors: Dmitry Tworowski, Ron Matsievitch, Vladimir Kogan