Abstract: Extracellular vesicles derived from native, photosynthetic, non-fermenting microalgae are provided. A method for isolating extracellular vesicles from native, photosynthetic, non-fermenting microalgae involving growth, centrifugation and ultracentrifugation steps is also provided. Use of the isolated extracellular vesicles as carriers for delivering diagnostic, therapeutic, nutraceutic and/or cosmetic agents is further provided.

Abstract: A portable mirror therapy device comprises a stiff divider panel attached to a base unit which supports the divider panel in an upright position to define two adjacent limb receiving spaces at opposite sides of the divider panel. A mirror is mounted on one face of the divider panel. A clamp mounted at a lower end of the divider panel cooperates with an underside of the base unit for securing the base unit on a support such as a table or worktop. An exercise apparatus is mounted on the device and includes a limb engaging member, which in this case comprises a handle at a mirror side of the divider panel. The exercise apparatus is a resistance load training system and comprises a load cord extending from the handle to an associated resistance element mounted within a housing on an opposite side of the divider panel to the mirror.