Abstract: The application relates to phthalazine derivatives of formula (I) which are inhibitors of PARP1, PARP2 and/or tubulin and thus useful for the treatment of cancer. Also disclosed are pharmaceutical formulations containing such compounds, as well as combinations of these compounds with at least one additional therapeutic agent.
Type:
Grant
Filed:
June 23, 2017
Date of Patent:
July 27, 2021
Assignees:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ATLASMEDX, INC.
Inventors:
Csaba J. Peto, David M. Jablons, Tsze Tsang, Hassan Lemjabbar-Alaoui
Abstract: This invention provides, among other things, compounds useful for treating diseases such as cancer, pharmaceutical formulations containing such compounds, as well as combinations of these compounds with at least one additional therapeutic agent.
Type:
Grant
Filed:
July 30, 2019
Date of Patent:
May 5, 2020
Assignees:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ATLASMEDX, INC.
Inventors:
Csaba J. Peto, David M. Jablons, Tsze Tsang, Hassan Lemjabbar-Alaoui
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