Patents Assigned to Atossa Genetics, Inc.
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Publication number: 20190298771Abstract: The present invention relates to compositions and transpapillary methods of adoptive cell therapy for the treatment of subjects having or at risk of having breast disorders.Type: ApplicationFiled: September 25, 2017Publication date: October 3, 2019Applicant: ATOSSA GENETICS INC.Inventor: Steven C. Quay
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Publication number: 20180200206Abstract: Methods and treatments are taught for the treatment of breast disorders, including proliferative breast disease, breast cancer, and increased breast density. The methods and compositions deliver efficacious formulations of chemical and/or biological treatment medicaments to the breast via a transpapillary route.Type: ApplicationFiled: July 14, 2016Publication date: July 19, 2018Applicant: Atossa Genetics Inc.Inventor: Steven C. Quay
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Patent number: 9052318Abstract: Biological samples of mammary fluid or components thereof are obtained using a breast pump device coupled with an absorbent paper or membrane, optionally facilitated by administering oxytocin to the subject. The breast pump device stimulates expression of mammary fluid and provides for collection of diagnostic samples on the absorbent paper or membrane to evaluate breast disease, including cancer. The biological sample may include fluid containing one or more of cells or cellular components, proteins, glycoproteins, peptides, nucleotides or other desired constituents comprising a breast disease marker. Absorbent paper or membrane, and methods relating to the paper or membrane, and a breast pump device are also provided.Type: GrantFiled: October 24, 2012Date of Patent: June 9, 2015Assignee: ATOSSA GENETICS, INC.Inventors: Steven C. Quay, Shu-Chih Chen
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Publication number: 20140221461Abstract: Provided in this application are formulations of double stranded RNA molecules and Krebs Cycle analogs that improving ribonuclease stability, reducing off-target effects of a double stranded siRNA molecule, or of reducing interferon responsiveness of a double stranded siRNA molecule using such dsRNA. Also disclosed are methods of treating a primary tumor or a metastasis by contacting circulating tumor cells, a primary tumor, or a metastasis with a described formulation.Type: ApplicationFiled: April 11, 2014Publication date: August 7, 2014Applicant: Atossa Genetics, Inc.Inventor: Steven C. QUAY
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Publication number: 20130130310Abstract: Biological samples of mammary fluid or components thereof are obtained using a breast pump device coupled with an absorbent paper or membrane, optionally facilitated by administering oxytocin to the subject. The breast pump device stimulates expression of mammary fluid and provides for collection of diagnostic samples on the absorbent paper or membrane to evaluate breast disease, including cancer. The biological sample may include fluid containing one or more of cells or cellular components, proteins, glycoproteins, peptides, nucleotides or other desired constituents comprising a breast disease marker. Absorbent paper or membrane, and methods relating to the paper or membrane, and a breast pump device are also provided.Type: ApplicationFiled: October 24, 2012Publication date: May 23, 2013Applicant: Atossa Genetics, Inc.Inventor: Atossa Genetics, Inc.
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Publication number: 20130121968Abstract: The present invention describes changes in bacterial gastrointestinal, cutaneous and nasal microbiota associated various mammalian medical conditions. Described are diagnostic tests that arise from combining phylogenetic information about the families, genus, and species of the microbiome and their relative abundance with the metabolic information contained in the metatranscriptome to determine the presence and absence of a disease or medical condition. Provided are compositions of bacteria, co-cultures of bacteria and a carrier for use in treating the disclosed medical conditions. The described compositions restore or correct disease- or medical condition-related imbalances in the microbiome profile with culture-conditioned formulations in which the transcriptome activity of the administered organisms is optimized. Alternatively, formulations of metabolites that drive changes in the metatranscriptome native to the mammal that treat disease or a medical condition or restore health are taught.Type: ApplicationFiled: October 3, 2012Publication date: May 16, 2013Applicant: Atossa Genetics, Inc.Inventor: Atossa Genetics, Inc.
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Publication number: 20130115629Abstract: Methods of diagnosing breast cancers are provided. The methods include analyzing the expression patterns of biomarkers in a plurality of cells to distinguish between invasive and non-invasive cancers, usual and atypical hyperplasias, and basal-like breast cancers. Breast cancers are diagnosed based upon different combinations of the biomarkers found in nipple aspirate fluid.Type: ApplicationFiled: October 24, 2012Publication date: May 9, 2013Applicant: Atossa Genetics, Inc.Inventor: Atossa Genetics, Inc.
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Publication number: 20130078650Abstract: Methods and systems for identifying material from a breast duct using one or more markers that can be identified in ductal fluid retrieved from the breast are provided.Type: ApplicationFiled: November 16, 2012Publication date: March 28, 2013Applicant: ATOSSA GENETICS, INC.Inventor: ATOSSA GENETICS, INC.
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Publication number: 20120214245Abstract: The invention relates to a simple screening test for neoplasia, a precancerous condition, or cancer of the breast. A method is described whereby a breast cancer marker is detected in breast fluid. In a particular embodiment, the method involves treating samples of breast fluids with an aldehyde detecting reagent without any prewashing. The appearance in breast fluids of a marker that is detected by an aldehyde detecting reagent, such as a Schiff's reagent, correlates very well with the disease status of the breast cancer subjects from which the fluids were obtained. Screening test kits are also provided.Type: ApplicationFiled: February 8, 2012Publication date: August 23, 2012Applicant: Atossa Genetics, Inc.Inventors: Jiri Jan Krepinsky, Rudolf Furrer, Ka Sing Yeung
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Publication number: 20120149761Abstract: Provided in this application are formulations of double stranded RNA molecules and Krebs Cycle analogs that improving ribonuclease stability, reducing off-target effects of a double stranded siRNA molecule, or of reducing interferon responsiveness of a double stranded siRNA molecule using such dsRNA. Also disclosed are methods of treating a primary tumor or a metastasis by contacting circulating tumor cells, a primary tumor, or a metastasis with a described formulation.Type: ApplicationFiled: August 27, 2010Publication date: June 14, 2012Applicant: Atossa Genetics, Inc.Inventor: Steven C. Quay
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Patent number: 8133737Abstract: The invention relates to a simple screening test for neoplasia, a precancerous condition, or cancer of the breast. A method is described whereby a breast cancer marker is detected in breast fluid. In a particular embodiment, the method involves treating samples of breast fluids with an aldehyde detecting reagent without any prewashing. The appearance in breast fluids of a marker that is detected by an aldehyde detecting reagent, such as a Schiff's reagent, correlates very well with the disease status of the breast cancer subjects from which the fluids were obtained. Screening test kits are also provided.Type: GrantFiled: January 31, 2011Date of Patent: March 13, 2012Assignee: Atossa Genetics, Inc.Inventors: Jiri Jan Krepinsky, Rudolf Furrer, Ka Sing Yeung
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Publication number: 20120034644Abstract: Methods and systems for identifying material from a breast duct using one or more markers that can be identified in ductal fluid retrieved from the breast are provided.Type: ApplicationFiled: August 15, 2011Publication date: February 9, 2012Applicant: Atossa Genetics, Inc.Inventor: David T. Hung