Patents Assigned to Atrix Laboratories, Incorporated
  • Patent number: 5733950
    Abstract: A biodegradable polymer is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to form the implant in-situ. A thermoplastic system to form said implant comprises the steps of dissolving a non-reactive polymer in biocompatible solvent to form a liquid, placing the liquid within the animal, and allowing the solvent to dissipate to produce the implant. An alternative, thermosetting system comprises mixing together effective amounts of a liquid acrylic ester terminated, biodegradable prepolymer and a curing agent, placing the liquid mixture within an animal and allowing the prepolymer to cure to form the implant. Both systems provide a syringeable, solid biodegradable delivery system by the addition of an effective level of biologically active agent to the liquid before injection into the body.
    Type: Grant
    Filed: September 25, 1995
    Date of Patent: March 31, 1998
    Assignee: Atrix Laboratories, Incorporated
    Inventors: Richard L. Dunn, James P. English, Donald R. Cowsar, David P. Vanderbilt