Abstract: In certain aspects of the present disclosure, a method for rapid informatics-based prognosis development includes receiving a consult request. The method includes selecting a study template configured to design a study to develop a consult output in response to the consult request. The method includes receiving a completed study template, including a completed field in the study template based on information from the consult request, the completed field comprising a variable provided in at least one of a timeframe field, a phenotype field, a cohort field, and a demographic field. The method includes obtaining cohort data based on the completed study template, the cohort data derived from a plurality of patient objects. The method includes generating the consult output based on the cohort data, the consult output comprising a result from an analysis of the cohort data according to a criteria and an instruction in the study template.