Patents Assigned to Atsuo Hazato
  • Isocarbacyclin derivatives as apoptosis inhibitors
    Patent number: 6087395
    Abstract: The present invention provides an apoptosis inhibitor containing a 15R-isocarbacyclin derivative or a 15-deoxy-isocarbacyclin derivative, which can be manufactured easily and economically by means of chemical synthesis.
    Type: Grant
    Filed: October 16, 1998
    Date of Patent: July 11, 2000
    Assignees: Japan Science and Technology Corporation, Atsuo Hazato
    Inventors: Yasuyoshi Watanabe, Atsuo Hazato, Masaaki Suzuki, Yumiko Watanabe, Takumi Sato
  • Isocarbacyclin derivatives
    Patent number: 5700833
    Abstract: The present invention provides novel isocarbacyclin derivatives useful for search and study of prostacyclin receptor and as a therapeutic drug for central nervous system diseases, which derivatives are expressed by the following formula ?I!: ##STR1## ?where, R.sup.1 represents a hydrogen atom, an alkyl group, or cation of an appropriate amount, and R.sup.2 an alkylene group.
    Type: Grant
    Filed: January 31, 1996
    Date of Patent: December 23, 1997
    Assignees: Research Developement Corporation of Japan, Atsuo Hazato
    Inventors: Yasuyoshi Watanabe, Masaaki Suzuki, Atsuo Hazato, Bengt Langstrom