Abstract: A magnetic flux pad for generating or receiving magnetic flux has two pole areas (11, 12), a permeable core (14) and a coil (16) wound about the core. The pad allows useable flux to be generated at a significant height above a surface of the pad.

Abstract: Embodiments of the invention relate to a method of extracting eye velocity information from a video footage having a plurality of frames, comprising detecting at least part of an eye in at least two frames of the video footage, applying an optical flow algorithm to the at least two frames of the video footage to extract pixel velocity information, and determining a statistical measure from the pixel velocity information within the detected at least part of the eye. Other embodiments of the invention relate to a method of extracting head image trajectory information from a video footage having a plurality of frames, comprising detecting at least part of a facial region of the head image in at least two frames of the video footage, determining a measure of the movement of the at least part of a facial region between the at least two frames, and determining a transformation map from the measure of the movement.

Abstract: Antifungal compounds, an antifungal compound extracted from Epicoccum purpurascens, also known as Epicoccum nigrum, methods of producing the antifungal compounds, isolates and compositions comprising the antifungal compounds, and methods of using the antifungal compounds.

Abstract: A magnetic flux pad for receiving or generating magnetic flux. The pad includes two pole areas (11, 12) associated with a magnetically permeable core 14. Coils 17 define the pole areas. The pad allows useable flux to be generated at a significant height above a surface of the pad.

Abstract: A heat exchanger 10 includes a conduit 12 for conveying cooling fluid relative to a body to be cooled. A heat transfer arrangement 62 is arranged in communication with an interior of the conduit 12, the heat transfer arrangement 62 and the conduit 12 together defining an assembly that is mountable adjacent the body to be cooled, convective heat exchange occurring, in use, due to movement of the cooling fluid relative to the body and to the heat transfer arrangement 62 of the assembly and radiant heat exchange occurring between the body and at least part of the heat transfer arrangement 62 of the assembly.

Abstract: The present invention is concerned with methods for reprogramming of mammalian somatic cells and in particular to reprogramming of mature mammalian somatic cells into multi-potent precursor cells.

Abstract: A device comprising an operating system to run processes and a middleware layer operable to launch applications. An application launched by the middleware layer is run using one or more processes in the operating system. The operating system has a user layer and a kernel wherein the processes run in the user layer and interact with other processes running in the user layer through the kernel, the interaction being in response to calls to the kernel made by the processes. The device has one or more policy files defining policies for interaction of processes with the kernel of the device, and a monitor configured to monitor interaction of a process with the kernel to link or associate defined policies to the process, and to read code defined in the policy file or files linked or associated to the process.

Abstract: The present invention provides a method for obtaining feedback parameters related to the state of a dielectric elastomer (DE). The method comprises introducing a small-scale oscillation to the voltage difference between electrodes of the DE, monitoring or repeatedly measuring several measurable electrical characteristics of the DE, deriving other relevant data from the measurements, deriving an equation for a plane of best fit through the relevant data when defined as orthogonal axes, and deriving the feedback parameters from coefficients of the plane equation. The method thus provides important feedback regarding the capacitance, leakage current and/or electrode resistance of the DE. Also disclosed are a computer program and a system adapted to perform the method.

Abstract: The present application relates to the detection of moving vehicles and other objects, in particular though not exclusively for the application of switching stationary charging pads for moving electric vehicle charging. There is provided an electric vehicle detecting apparatus for switching a charging pad for charging a vehicle transmitting a locating signal, the apparatus comprising two sensors separated in the direction of travel of the vehicle, and a detector arranged to detect the vehicle by comparing the locating signals received by each of the two sensors.

Abstract: This invention relates to a device for controlling of movement of limbs of a user in a substantially mirror symmetrical manner, a user's limb or limbs being held in position via support arms, said device comprising a bar (or bars) adapted to move about a point of rotation, said bar (or bars) having a first end and a second end, said ends separated by the point of rotation, a first support arm(s) operatively coupled at or towards one end of said bar and a second support arm(s) operatively coupled at or towards a different end of the bar wherein the first and second support arms are adapted to substantially support and/or hold the limbs of a user of said device, the first and second support arms and the bar (or bars) configured such that, in use, as the bar (or bars) rotate(s) the support arms move in a substantially tandem synchronized manner with respect to each other.

Abstract: The invention provides kinase inhibitors of Formula I: wherein either: (1) R1 is H, and (a) R2 is (3-chlorobenzyl)oxy-and R3 is chloro; (b) R2 and R3, together with the carbon atoms to which they are attached, form 1-(3-fluorobenzyl)-1H-pyrazole; (c) R2 is 2-pyridinylmethoxy and R3 is chloro; (d) R2 and R3 are both chloro; (e) R2 is chloro and R1 is bromo; (f) R2 and R3 are both bromo; (g) R2 is fluoro and R3 is ethynyl; (h) R2 is chloro and R3 is ethynyl; (i) R2 is bromo and R3 is ethynyl; (j) other than when R1 is in the 3-position in combination with R3, in the 4-position, R2 is bromo and R3 is fluoro; (k) R2 is 2-pyridinylmethoxy and R3 is fluoro; or (l) R2 is 2-pyridinylmethoxy and R1 is bromo; or (2) at least one of R1, R2 and R3 is selected from benzyloxy, 3-chlorobenzyloxy and 2-pyridinylmethoxy and when at least one of R1, R2 and R3 is not benzyloxy, 3-chlorobenzyloxy or 2-pyridinylmethoxy, each of the others is independently selected from H, halogen, and C2-C4 alkynyl, with the proviso that

Abstract: Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.

Abstract: A system for orienting particles in a microfluidic system includes one or more radiation pressure sources arranged to expose particles to radiation pressure to cause the particles to adopt a particular orientation in the fluid. A system for sorting particles in a microfluidic system includes a detection stage arranged to detect at least one difference or discriminate between particles in the fluid flow past the detection stage, and one or more radiation pressure sources past which the particles move sequentially and a controller arranged to switch radiation energy to cause a change in direction of movement of selected particles in the fluid flow to sort the particles. The particles may be biological particles such as spermatazoa. The radiation pressure may be optical pressure and may be from one or more waveguides which may extend across a channel of the microfluidic system.

Abstract: The present invention provides methods for inhibiting growth and proliferation of HIF pathway proficient cells by administering GLUT1 inhibitors of the invention to HIF pathway proficient cells.

Abstract: The invention provides novel prodrug compounds comprising a kinase inhibitor and a reductively-activated fragmenting aromatic nitroheterocycle or aromatic nitrocarbocycle trigger, where the compound carries a positive charge. In preferred embodiments, the compounds are of Formula I: where: X is any negatively charged counterion; R1 is a group of the formula —(CH2)nTr, where Tr is an aromatic nitroheterocycle or aromatic nitrocarbocycle and —(CH2)nTr acts as a reductively-activated fragmenting trigger; and n is an integer from 0 to 6; R2, R3 and R4 may each independently be selected from aliphatic or aromatic groups of a tertiary amine kinase inhibitor (R2)(R3)(R4)N, or two of R2, R3, and R4 may form an aliphatic or aromatic heterocyclic amine ring of a kinase inhibitor, or one of R2, R3 and R4 may be absent and two of R2, R3 and R4 form an aromatic heterocyclic amine ring of a kinase inhibitor. The compounds of the invention are useful in treating proliferative diseases such as cancer.

Abstract: A method of controlling power delivered to one or more loads in an inductive power transfer (IPT) system includes varying a frequency of a current in a primary conductive path (109), detecting the frequency in a pick-up inductively coupled with the primary conductive path (109), and controlling the power supplied to a load (207) associated with the pickup dependent on the detected frequency of the current in the primary conductive path (109). The frequency of the current is determined by is determined by either or both the load on a power supply (104) of the IPT system or the load on an electricity supply network supplying the power supply (104).

Abstract: A magnetic flux pad for receiving or generating magnetic flux. The pad includes two pole areas (11, 12) associated with a magnetically permeable core 14. Coils 17 define the pole areas. The pad allows useable flux to be generated at a significant height above a surface of the pad.

Abstract: The present invention provides an inductively powered sensor system having a primary conductive path capable of being energized to provide an electromagnetic field in a defined space. An inductive power pick-up is associated with a sensor and is capable of receiving power from the field to supply the sensor. The system includes a first sensing unit to sense the power available to the pick-up and a control unit to increase or decrease the power available to the sensor dependant on the sensed power available. A method of inductively powering a sensor, an inductively powered sensor and an animal enclosure including one or more primary conductive path of an inductive power supply are also disclosed.

Abstract: A magnetic flux coupler comprising a magnetically permeable core having a first axis, two coils magnetically associated with the core, each coil defining a pole area located on a first side of the core and the pole areas being separated along the first axis, the coils each having a central region located between the pole areas, an end region opposite to the central region, and a side region between the central region and the end region, wherein an auxiliary pole area is provided beyond the end region of each coil which absorbs leakage flux which would otherwise emanate from the each coil in use in the vicinity of the end region.

Abstract: The invention comprises a process comprising infiltrating or infiltrating and coating a substrate with a boron-comprising precursor, and contacting the boron-comprising precursor with a nitrogen-comprising reactant to convert the boron-comprising precursor to BN or other a boron-nitrogen reaction product in the surface porosity or in the surface porosity and on the surface of the substrate. Composite materials comprising as one phase a substrate and BN or other a boron-nitrogen reaction product as a further phase, in surface porosity or in surface porosity and on a surface of the substrate, are claimed.