Patents Assigned to AUM LifeTech, Inc
  • 2?F-ANA-LET7 mediated utrophin upregulation for DMD therapy
    Patent number: 12104152
    Abstract: The invention relates to compositions and methods for enhancing or upregulating utrophin protein production and methods for treating myopathies, such as Duchenne Muscular Dystrophy (DMD). Specifically, the invention relates to compositions, such as oligonucleotides, and methods for enhancing or upregulating utrophin in a subject by blocking binding of let-7c miRNA to the utrophin mRNA 3 untranslated region (UTR).
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: October 1, 2024
    Assignees: The Trustees of the University of Pennsylvania, AUM LifeTech, Inc
    Inventors: Tejvir S. Khurana, Manoj Kumar Mishra, Veenu Aishwarya
  • 2'F-ANA-LET7 MEDIATED UTROPHIN UPREGULATION FOR DMD THERAPY
    Publication number: 20210040481
    Abstract: The invention relates to compositions and methods for enhancing or upregulating utrophin protein production and methods for treating myopathies, such as Duchenne Muscular Dystrophy (DMD). Specifically, the invention relates to compositions, such as oligonucleotides, and methods for enhancing or upregulating utrophin in a subject by blocking binding of let-7c miRNA to the utrophin mRNA 3 untranslated region (UTR).
    Type: Application
    Filed: March 18, 2019
    Publication date: February 11, 2021
    Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, AUM LifeTech, Inc
    Inventors: Tejvir S. KHURANA, MANOJ KUMAR MISHRA, Veenu AISHWARYA