Abstract: This invention is directed to a composition and method for the buccal delivery of sea cucumber extract. The composition for the buccal delivery of sea cucumber extract comprises a substantially uniform mixture of an effective amount of sea cucumber extract and sugar. In one embodiment of the invention, the sea cucumber extract is approximately 5% to approximately 35% by weight of the sea cucumber tablet formulation. In another embodiment of the invention, the composition for the buccal delivery of sea cucumber tablets comprises a substantially uniform mixture of an effective amount of sea cucumber extract and a sugar and an artificial sweetener. The compression process for the production of the buccal tablets uses lower pressure than conventional tableting pressures. The above dosage units dissolve quickly in the buccal cavity allowing rapid absorption of the sea cucumber tablets through the buccal mucus membrane into the systemic bloodstream.