Patents Assigned to Aurobindo Pharma Ltd.
  • Pharmaceutical composition of ivermectin and process for preparation thereof
    Patent number: 11160780
    Abstract: The invention relates to a topical pharmaceutical composition comprising effective amount of ivermectin as an active agent, process of preparation thereof and method of treating dermatological conditions such as inflammatory lesions of rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acne form rashes, and the like.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: November 2, 2021
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Biswajit Saha, Nilendu Sen, Sivakumaran Meenakshisunderam
  • Process for the preparation of Eltrombopag olamine and its intermediates
    Patent number: 11161821
    Abstract: The present invention relates to an improved process for the purification of Eltrombopag olamine of compound of formula (2). The present invention also relates to an improved process for the preparation of Eltrombopag olamine intermediates and further conversion to Eltrombopag olamine of a compound of formula (2).
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: November 2, 2021
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Moturu Venkata Ramakrishna Murthy, Tiwari Shashi Kant, Nadakudity Sailendra Kumar, Samala Bhanuchander, Rajesh Chennuri, Srinivasa Chary Katuroju, Sivakumaran Meenakshisunderam
  • Naloxegol oxalate and solid dispersion thereof
    Patent number: 11077103
    Abstract: The present invention relates to solid dispersion of Naloxegol oxalate. Further, the present invention relates to an improved process for Naloxegol oxalate and intermediates thereof.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: August 3, 2021
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Rama Shankar, Nimesh Chandra Misra, Siva Rama Kasibabu Velegula, Suresh Chapala, Sivakumaran Meenakshisunderam
  • Process for the preparation of phenoxybenzamine
    Patent number: 10906866
    Abstract: The present invention provides a process for the preparation of N-phenoxyisopropyl ethanolamine of Formula (II) and its conversion to Phenoxybenzamine of Formula (I) or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: February 2, 2021
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Shashi Kant Tiwari, Rajesh Chennuri, Bhanuchandar Samala, Venkata Ramana Kintali, Sivakumaran Meenakshisunderam
  • Process for the preparation of docosanol
    Patent number: 10836693
    Abstract: The present invention provides a process for the preparation of Docosanol (I). The process comprises reducing cis-13-Docosenoic acid (V) to obtain Docosanoic acid (III), which is further reduced to obtain Docosanol (I).
    Type: Grant
    Filed: May 28, 2018
    Date of Patent: November 17, 2020
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Nandi Sukumar, Theriviam Sudalayandi Shanmugam Sundaram Dhanraj, Sreedhar Reddy Dwarakapally, Ravi Kumar Gupta Miriyala, Sivakumaran Meenakshisunderam
  • A process for the preparation of Deferasirox
    Publication number: 20200207725
    Abstract: The present invention provides an improved process for the preparation of Deferasirox of Formula-I substantially free from ‘hydrazino impurity’ by the condensation of 2-(2-hydrophenyl)-4H-1,3-benzoxazin-4-one of Formula-IV with 4-hydrazino benzoic acid of Formula-V in a polar solvent.
    Type: Application
    Filed: July 2, 2018
    Publication date: July 2, 2020
    Applicant: Aurobindo Pharma Ltd.
    Inventors: Hero Velladurai, Janardhana Rao Vascuri, Ravi Shankar Sathu, Sivakumaran Meenakshiaunderam
  • Process for the preparation of Mirabegron alpha-form crystals
    Patent number: 10253005
    Abstract: The present invention provides a process for the preparation of ?-Form crystals of Mirabegron using a solvent selected from water.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: April 9, 2019
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sukumar Nandi, Shantan Kumar Reddy, Gona Bala Narashimha Reddy, Sivakumaran Meenakshisundaram
  • Pharmaceutical Composition Comprising Canagliflozin, Process of Preparation and Use Thereof
    Publication number: 20190070120
    Abstract: The present invention relates to a binder tree pharmaceutical composition comprising canagliflozin or a prodrug or a pharmaceutically acceptable salt thereof, and one or more 5 pharmaceutically acceptable excipients, wherein the said composition is devoid of canagliflozin hemihydrate, and having acceptable chemical stability, polymorphic stability & comparative dissolution and bioequivalence profile to that of INVOKANA® tablets.
    Type: Application
    Filed: March 9, 2017
    Publication date: March 7, 2019
    Applicant: Aurobindo Pharma Ltd.
    Inventors: Satyabrata Barik, Venugopala Chokkasandra Jayarama Reddy, Sivakumaran Meenakshisundaram
  • Pharmaceutical compositions of Linagliptin and process for preparation thereof
    Publication number: 20180250304
    Abstract: Pharmaceutical compositions comprising an antidiabetic agent as an active agent are provided. The present invention relates to pharmaceutical compositions comprising linagliptin or a pharmaceutically acceptable salt thereof as an active agent. The present invention also relates to process of preparation of pharmaceutical compositions comprising linagliptin or a pharmaceutically acceptable salt thereof. The present invention also relates to method of administering the compositions comprising linagliptin to a subject in need thereof.
    Type: Application
    Filed: April 23, 2018
    Publication date: September 6, 2018
    Applicant: Aurobindo Pharma Ltd.
    Inventors: Venugopala Chokkasandra Jayaramareddy, Sreenivas Reddy, Chandrashekhar Shriram Kandi, Sivakumaran Meenakshisunderam
  • Solvates of darunavir
    Patent number: 9643976
    Abstract: The present invention relates to novel solvates of Darunavir of Formula I.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: May 9, 2017
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Anand Gopalkrishna Kamat, Naga Trinadhachari Ganala, Venkata Balaji Boddu, Joseph Prabahar Koilpillai, Sivakumaran Meenaakshisunderam
  • An improved process for the preparation of Dolutegravir
    Publication number: 20160108058
    Abstract: The present invention provides (R)-3-Amino-1-butanol (D)-tartarate (IIb); process for its preparation and its conversion to Dolutegravir. The present invention also provides an improved process for the preparation of Dolutegravir (I) or pharmaceutically acceptable salts wherein compound (XVI) is reacted with an optically active acid addition salt of (R)-3-amino-1-butanol (IIa).
    Type: Application
    Filed: February 7, 2014
    Publication date: April 21, 2016
    Applicant: Aurobindo Pharma Ltd.
    Inventors: Shankar Reddy Budidet, Nageshwar Dussa, Gowrisankar Rao Kaki, Srinivasa Rao Yatcherla, Jagan Mohan Reddy Sanapureddy, Subba Reddy Danda, Srinivasachary Katuroju, Sivakumaran Meenakshisunderam
  • Pharmaceutical compositions of Linagliptin and process for preparation thereof
    Publication number: 20150283248
    Abstract: Pharmaceutical compositions comprising an antidiabetic agent as an active agent are provided. The present invention relates to pharmaceutical compositions comprising linagliptin or a pharmaceutically acceptable salt thereof as an active agent. The present invention also relates to process of preparation of pharmaceutical compositions comprising linagliptin or a pharmaceutically acceptable salt thereof. The present invention also relates to method of administering the compositions comprising linagliptin to a subject in need thereof.
    Type: Application
    Filed: March 31, 2015
    Publication date: October 8, 2015
    Applicant: AUROBINDO PHARMA LTD.
    Inventors: Venugopala Chokkasandra Jayaramareddy, Sreenivas Reddy, Chandrashekhar Shriram Kandi, Sivakumaran Meenakshisunderam
  • Process for the manufacture of rosuvastatin calcium using crystalline rosuvastatin ethyl ester
    Patent number: 8846915
    Abstract: The present invention relates to an improved process to prepare Rosuvastatin calcium of Formula (I), with good quality. Further, the present invention also relates to a crystalline polymorphic form of Rosuvastatin ethyl ester.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: September 30, 2014
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Ganagadnar Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for the preparation of Dutasteride
    Patent number: 8563728
    Abstract: The present invention provides an improved process for the preparation of Dutasteride (I) which comprises: (i) reacting 4-aza-5?-androst-1-en-3-one-17?-carboxylic acid (VII), Formula VII with sulfonic acid anhydride (RSO2)2O in presence of base to produce an intermediate compound of Formula (XIII), wherein R represents C1-6 alkyl, C1-6 halo alkyl, C6-10 aryl, halo aryl; (ii) condensing compound of Formula (XIII) with 2,5-bis(trifluoromethyl)aniline (III), Formula (III) in the presence or absence of a base to produce Dutasteride (I).
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: October 22, 2013
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Balanarasimha Reddy Gona, Naresh Akkina, Rani Ananta, Islam Aminul, Sivakumaran Meenakshisunderam
  • Process for preparing pyrimidine propenaldehyde
    Patent number: 8394956
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of formula (I), which is an useful intermediate in the preparation of Rosuvastatin.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: March 12, 2013
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhara Bhima Shankar Nangi, Rani Ananta, Sivakumaran Meenakshisunderam
  • Process for the preparation of substantially pure (2S,3S,5S)-5-amino-2-N,N-dibenzylamino-3-hydroxy-1,6-diphenylhexane
    Patent number: 8236991
    Abstract: The present invention relates to the purification of (2S,3S,5S)-5-amino-2-N,N-dibenzylamino-3-hydroxy-1,6-diphenylhexane (III) by making its crystalline acid addition salt, which can be used as such to produce Lopinavir/Ritonavir with high purity and yield.
    Type: Grant
    Filed: June 5, 2008
    Date of Patent: August 7, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: V Raghava Reddy Ambati, Srinivas Garaga, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for preparation of rosuvastatin calcium field of the invention
    Patent number: 8212035
    Abstract: The present invention relates to an improved process for preparing (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium of Formula (I).
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nandi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • Process for preparing rosuvastatin calcium
    Patent number: 8212034
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-iso-propyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of Formula I which is an intermediate useful in the preparation of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid]calcium salt of Formula II.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • Process for preparing nevirapine
    Patent number: 8212025
    Abstract: An improved process for preparing 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2?,3?-e][1,4]diazepin-6-one of Formula (I).
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Jagan Mohan Reddy Sanapureddy, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for the preparation of Irbesartan
    Patent number: 8106216
    Abstract: The present invention relates to an improved process for the preparation of 2-n-butyl-3-[[2?-(1H-tetrazol-5-yl)[1,1?-biphenyl]-4-yl]-1,3-diazaspiro[4.4]non-1-en-4-one (Irbesartan).
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: January 31, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Venkata vara prasada rao Korrapati, Venkata subramanyeswara rao Inti, Rani Ananta, Ramesh Dandala, Sivakumaran Meenakshisunderam