Abstract: The invention describes the isolation and methods of use of a non-senescent pool of adult cardiac stem cells. In particular, a subset of adult cardiac stem cells with superior regenerative capacity is disclosed. Such cells were found to have immortal DNA. Compositions comprising the non-senescent stem cells are also described. In addition, the present invention provides methods for repairing aged myocardium or damaged myocardium using the isolated non-senescent adult cardiac stem cells.
Type:
Grant
Filed:
August 19, 2013
Date of Patent:
May 9, 2017
Assignee:
AUTOLOGOUS REGENERATION, LLC
Inventors:
Piero Anversa, Annarosa Leri, Jan Kajstura