Abstract: A unitary, hermetically-sealed dispensing container, having plural removable closures and suitable for containing and dispensing sterile solutions, is provided. The removable closures are unitary with the container. The dispensing container comprises a sealed, elongated shell of thermoplastic material provided with at least one access port at each end of the shell, a neck portion unitary with the shell and surrounding each access port, and removable cap means over the access ports and joined to the corresponding neck portions by means of frangible annular webs. The frangible annular webs are unitary with the cap means and with the neck portions. At least one of the neck portions is provided with a bore of predetermined controlled dimensions and is adapted to receive a draining spike or a similar means for withdrawing the contents of the container.

Abstract: A stopper is provided which is adapted to be held in place in an opening in a molded thermoplastic container that is molded about the stopper in place. The stopper has a substantially cylindrical body portion with a planar end surface at one end thereof and a unitary skirt portion depending from the other end of the body portion. An annular flange, unitary with the body portion, extends laterally away from the body portion in one end thereof to define first and second peripheral flange surfaces and a lateral flange surface. The first peripheral flange surface is contiguous with the planar end surface and with the lateral flange surface. The first peripheral flange surface further is disposed at an angle with respect to the planar end surface and converges towards the second peripheral flange surface in a direction away from the body portion. The second peripheral flange surface is contiguous with the lateral flange surface and the skirt portion.

Abstract: A hermetically sealed container with plural access ports is provided. The closure includes a severable dome unitary with the container and positioned over the container access opening. The dome is severable from the container by the action of a collar threadedly attached to the container. The dome is further provided with an access aperture that is closed off by a twist-off cap which, upon removal, exposes the dispensing aperture.

Abstract: A unitary, hermetically-sealed but pierceable dispensing container, suitable for packaging parenteral solutions, is made from a flexible, generally tubular body of thermoplastic material utilizing a form, fill and seal technique and a movable, composite mandrel that includes a forming ram member for compression molding from within the container a container wall portion which includes a pierceable membrane. The tubular body is closed at one end and terminates at the other end in a draining region having an access aperture or port sealed by a unitary membrane of predetermined thickness. The membrane permits penetration of a cannula therethrough without coring, and an annular sealing means surrounding the aperture is adapted for frictional and sealing engagement of the cannula after the membrane has been penetrated.

Abstract: A unitary, hermetically sealed but pierceable dispensing container, suitable for packaging parenteral solutions, is made from a flexible, generally tubular body of thermoplastic material utilizing a form, fill and seal technique and a movable, composite mandrel that includes a forming ram member for compression molding from within the container a container wall portion which includes a pierceable membrane. The tubular body is closed at one end and terminates at the other end in a draining region having an access aperture or port sealed by a unitary membrane of predetermined thickness. The membrane permits penetration of a cannula therethrough without coring, and an annular sealing means surrounding the aperture is adapted for frictional and sealing engagement of the cannula after the membrane has been penetrated.

Abstract: The hermetically sealed plastic container of the present invention has a body portion, a neck portion and a dispensing head all integrally formed. The containers furthermore preferably and advantageously are formed, filled and sealed in one continuous operation, automatically. The dispensing head is integrally molded with and atop the neck portion, and has an inside diameter which substantially corresponds with the outside diameter of the side wall of the neck portion so as to slidably and frictionally receive the neck portion within the dispensing head. A severable annular groove is provided between the neck portion and the dispensing head, with this annular groove being proportioned such that it can be severed by exerting a downward force on the dispensing head. Simultaneously, as the dispensing head is forcibly urged downwardly to sever the annular groove, the dispensing head is forcibly urged downwardly about the neck portion.