Abstract: The present disclosure provides methods and compositions for generating populations of auxotrophic cells and populations of differentiated cells and selecting populations of transfected cells using split auxotrophy.
Type:
Application
Filed:
May 8, 2020
Publication date:
October 13, 2022
Applicants:
AUXOLYTIC LTD, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Inventors:
James Patterson, Matthew Porteus, Volker Wiebking
Abstract: The present disclosure provides compositions and methods for producing and using modified auxotrophic host cells for improved therapy involving administration of an auxotrophic factor.
Type:
Application
Filed:
May 8, 2020
Publication date:
September 15, 2022
Applicants:
AUXOLYTIC LTD, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Inventors:
James Patterson, Matthew Porteus, Volker Wiebking
Abstract: The present disclosure provides compositions and methods for producing and using modified auxotrophic host cells for improved gene therapy involving administration of an auxotrophic factor.
Type:
Application
Filed:
November 4, 2020
Publication date:
February 25, 2021
Applicants:
AUXOLYTIC LTD, The Board of Trustees of the Leland Stanford Junior University
Inventors:
James PATTERSON, Matthew PORTEUS, Volker WIEBKING