Patents Assigned to Avalanche Australia Pty Ltd.
  • Treatment of ocular neovascularization using anti-VEGF proteins
    Patent number: 10004788
    Abstract: The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: June 26, 2018
    Assignee: Avalanche Australia Pty Ltd.
    Inventors: Ian J. Constable, P. Elizabeth Rakoczy, Chooi-May Lai, Thomas W. Chalberg, Jr.
  • Treatment of ocular neovascularization using anti-VEGF proteins
    Patent number: 9943573
    Abstract: The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: April 17, 2018
    Assignee: Avalanche Australia PTY Ltd.
    Inventors: Ian J. Constable, P. Elizabeth Rakoczy, Chooi-May Lai, Thomas W. Chalberg, Jr.
  • TREATMENT OF AMD USING AAV SFLT-1
    Publication number: 20150004101
    Abstract: The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject.
    Type: Application
    Filed: May 19, 2014
    Publication date: January 1, 2015
    Applicant: Avalanche Australia Pty Ltd.
    Inventors: Ian J. Constable, P. Elizabeth Rakoczy, Chooi-May Lai, Thomas W. Chalberg, JR.
  • TREATMENT OF AMD USING AAV SFLT-1
    Publication number: 20140371438
    Abstract: The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject.
    Type: Application
    Filed: May 19, 2014
    Publication date: December 18, 2014
    Applicant: Avalanche Australia Pty Ltd.
    Inventors: Ian J. Constable, P. Elizabeth Rakoczy, Chooi-May Lai, Thomas W. Chalberg, JR.
  • TREATMENT OF AMD USING AAV SFLT-1
    Publication number: 20140341977
    Abstract: The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject.
    Type: Application
    Filed: May 19, 2014
    Publication date: November 20, 2014
    Applicant: Avalanche Australia Pty Ltd.
    Inventors: Ian J. Constable, Elizabeth P. Rakoczy, Chooi-May Lai, Thomas W. Chalberg, JR.
  • TREATMENT OF AMD USING AAV SFLT-1
    Publication number: 20130323302
    Abstract: The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject.
    Type: Application
    Filed: May 7, 2013
    Publication date: December 5, 2013
    Applicants: Lions Eye Institute Limited, Avalanche Australia Pty Ltd.
    Inventors: Ian J. Constable, Elizabeth P. Rakoczy, Chooi-May Lai, Thomas W. Chalberg, JR.