Patents Assigned to Avanir Pharmaceutials
  • Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
    Patent number: 7435737
    Abstract: Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein n, R1, R2, R3, R4, X, Y and Z are as defined herein. Compositions containing an inhibitor of MIF in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: October 14, 2008
    Assignee: Avanir Pharmaceutials
    Inventors: Federico C. A. Gaeta, Andrew Baird, Jerry Anchin, Wenbin Ying, Robert Florkiewicz, Jagadish Sircar, Sunil Kumar K. C.