Abstract: The application describes methods for making a deuterated dextromethorphan of Formula (I), deuterated dextromethorphan produced by these methods, and pharmaceutically acceptable salts thereof.
Type:
Grant
Filed:
November 11, 2020
Date of Patent:
December 19, 2023
Assignee:
AVANIR PHARMACEUTICALS, INC.
Inventors:
Matt Johnson, Cunxiang Zhao, Weihua Meng, Zhijun Lu, Yan Li
Abstract: The application describes methods for making a deuterated dextromethorphan of Formula (I), deuterated dextromethorphan produced by these methods, and pharmaceutically acceptable salts thereof.
Type:
Grant
Filed:
June 24, 2020
Date of Patent:
December 15, 2020
Assignee:
Avanir Pharmaceuticals, Inc.
Inventors:
Matt Johnson, Cunxiang Zhao, Weihua Meng, Zhijun Lu, Yan Li
Abstract: The application describes methods for making a deuterated dextromethorphan of Formula (I), deuterated dextromethorphan produced by these methods, and pharmaceutically acceptable salts thereof.
Type:
Grant
Filed:
July 3, 2017
Date of Patent:
August 4, 2020
Assignee:
Avanir Pharmaceuticals, Inc.
Inventors:
Matt Johnson, Cunxiang Zhao, Weihua Meng, Zhijun Lu, Yan Li
Abstract: Pharmaceutical compositions and methods for treating neurological disorders by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine.
Type:
Application
Filed:
October 21, 2013
Publication date:
February 13, 2014
Applicant:
Avanir Pharmaceuticals, Inc.
Inventors:
Gerald Yakatan, James Berg, Laura E. Pope, Richard A. Smith
Abstract: Pharmaceutical compositions and methods for treating neurological disorders by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine. This invention also provides methods of reducing CNS and gastrointestinal side effects associated with a long term, dextromethorphan/low-dose quinidine combination therapy.
Abstract: Pharmaceutical compositions and methods for treating depression, anxiety, and neurodegenerative diseases and cognitive disorders, such as dementia and Alzheimer's disease, by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine.
Abstract: Pharmaceutical compositions and methods for treating neurological disorders by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine.
Abstract: Pharmaceutical compositions and methods for treating neurological disorders by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine.
Type:
Grant
Filed:
March 8, 2012
Date of Patent:
July 24, 2012
Assignee:
Avanir Pharmaceuticals, Inc.
Inventors:
Gerald Yakatan, James Berg, Laura Pope, Richard Alan Smith
Abstract: Pharmaceutical compositions and methods for treating neurological disorders by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine.
Type:
Application
Filed:
March 8, 2012
Publication date:
June 28, 2012
Applicant:
AVANIR PHARMACEUTICALS, INC.
Inventors:
Gerald YAKATAN, James Berg, Laura E. Pope, Richard A. Smith
Abstract: Pharmaceutical compositions and methods for treating neurological disorders by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine. This invention also provides methods of reducing CNS and gastrointestinal side effects associated with a long term, dextromethorphan/low-dose quinidine combination therapy.
Abstract: Pharmaceutical compositions and methods for treating depression, anxiety, and neurodegenerative diseases and cognitive disorders, such as dementia and Alzheimer's disease, by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine.
Abstract: Pharmaceutical compositions and methods for treating neurological disorders by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine.
Type:
Application
Filed:
February 3, 2010
Publication date:
June 3, 2010
Applicant:
AVANIR PHARMACEUTICALS, INC.
Inventors:
Gerald YAKATAN, James Berg, Laura E. Pope, Richard A. Smith
Abstract: Pharmaceutical compositions and methods for treating neurological disorders by administering same are provided. The compositions comprise dextromethorphan in combination with quinidine.
Type:
Grant
Filed:
January 12, 2005
Date of Patent:
February 9, 2010
Assignee:
Avanir Pharmaceuticals, Inc.
Inventors:
Gerald Yakatan, James Berg, Laura E. Pope, Richard A. Smith