Abstract: Thrombectomy systems having curved tubular cutting devices, and methods of using them, are provided. These systems, devices, and methods can (i) effectively cut and remove a variety of thrombus tissue from blood vessels, including soft, tough, and hard tissue; (ii) safely self-collect and remove tissue particles to avoid release of emboli; and, (iii) effectively treat a blood vessel with a reduced risk of suffering vessel injuries that can lead to increased stenosis.

Abstract: Disclosed are example embodiments of an endovascular coil having a twisted figure 8 shape. The endovascular coil includes: a first loop; a second loop; and an inflection region where a portion of the first loop transitions into a portion of the second loop. The second loop is rotated about an axis parallel to the longitudinal axis of the first loop to create the twisted figure 8 shape. The twist adds more randomness and variability to the filling behavior of the endovascular coil. The added randomness and variability enables the twisted figure 8 coil to better fill the void of irregular-shaped aneurysms than other conventional embolic coils.

Abstract: Telescoping, self-driving, and laterally-pushing atherectomy devices are provided, each having a flexible sheath, a cutter with helical flutes, and a drive assembly. The drive assembly can have a flexible driveshaft that is rotatably translational with the lumen of the flexible sheath, a positive displacement pump that begins pumping at the distal end of the drive shaft adjacent to the helical flutes at the proximal end of the cutter, and the flexible drive shaft can be longer than the flexible sheath to enable a reversible telescoping of the drive assembly from the lumen of the flexible sheath. The positive displacement pump can be a screw pump having a drive screw portion extending beyond the flexible sheath, exposed for contact with a vascular lumen for the self-driving. And, the devices can have a reversibly-expandable, lateral pushing member at the distal end of the flexible sheath for the lateral pushing.

Abstract: Funnel-trap type delivery and/or retrieval devices for Inferior Vena Cava (IVC) filters or other medical implants are described in which the devices comprise two layers of braid with an axially support member. The support member may be interposed between braid layers or set inside the braid layers but interposed between heatset features. Delivery and/or retrieval devices, kits in which they are included, methods of use and methods of manufacture are all contemplated herein.

Abstract: After a prolonged period in the body, an IVC filter can be substantially absorbed by the body. When this occurs, it can be very difficult and/or dangerous for the patient if the IVC filter is forcibly removed. Thus, it is desirable to have systems and methods for safely abandoning the removal procedure of the IVC filter. Example embodiments of an apparatus for safely abandoning the removal procedure of the IVC filter can include: a sleeve having a lumen and a first hole on a wall of the sleeve; a shaft slidably disposed within the lumen of the sleeve; a flexible distal extension comprising a braid structure with a first opening; and a first lasso encircling a portion of the first opening of the braid.

Abstract: The embodiments described relate to retrieving temporary Inferior Vena Cava (IVC) filters and other endovascular implants or foreign bodies. Features are provided for effective actuation in closing an inner aperture of the embodiments.

Abstract: An embolic device and a corresponding embolic device delivery system and method. In one example, an embolic device delivery system comprises a delivery catheter, a coupler disposed inside the delivery catheter, and an embolic device that may be carried and placed by the coupler. The embolic device includes a primary winding that forms a hollow tube such that a coupler may be threaded therethrough. Further, the embolic device may include a slotted metal tube suited to be affixed to one end of the hollow tube formed by the primary winding. Additionally, the embolic device may include a retaining mechanism that includes one or more protrusions suited to engage with one or more slots of the slotted metal tube. In this manner, the retaining mechanism is affixed to the slotted metal tube and the hollow tube formed by the primary winding.

Abstract: Telescoping, self-driving, and laterally-pushing atherectomy devices are provided, each having a flexible sheath, a cutter with helical flutes, and a drive assembly. The drive assembly can have a flexible driveshaft that is rotatably translational with the lumen of the flexible sheath, a positive displacement pump that begins pumping at the distal end of the drive shaft adjacent to the helical flutes at the proximal end of the cutter, and the flexible drive shaft can be longer than the flexible sheath to enable a reversible telescoping of the drive assembly from the lumen of the flexible sheath. The positive displacement pump can be a screw pump having a drive screw portion extending beyond the flexible sheath, exposed for contact with a vascular lumen for the self-driving. And, the devices can have a reversibly-expandable, lateral pushing member at the distal end of the flexible sheath for the lateral pushing.

Abstract: Funnel-trap type devices made of shape-set (e.g., heatset) braid for delivery and/or retrieval of Inferior Vena Cava (IVC) filters or other medical devices are described. Delivery and/or retrieval devices, kits in which they are included, methods of use and methods of manufacture are all contemplated herein.

Abstract: A system and method for delivering an embolic device are disclosed. In one embodiment, the system and method may be directed to a combination of a catheter, coupler, and embolic device. The coupler is disposed inside of the catheter. The embolic device is coupled with a retaining mechanism at the proximal end. Until the embolic device is delivered to a certain location within an artery, the embolic device is engaged with the catheter by engaging the coupler with the retaining mechanism. The embolic device is further secured to the delivery catheter by securing the coupler with a securing mechanism formed on the catheter. When the delivery catheter reaches the desired location in the artery, the embolic device is released from the delivery catheter by simply pulling the coupler proximally such that the loop portion of the coupler first becomes disengaged from the locking window and then from the retaining mechanism.

Abstract: Funnel-trap type devices are described that are made of shape-set (e.g., heatset) braid for delivery and/or retrieval of Inferior Vena Cava (IVC) filters or other medical devices. Delivery and/or retrieval devices, kits in which they are included, methods of use and methods of manufacture are all contemplated. Additional forming tooling, methods and device embodiment shapes are described herein.

Abstract: Methods and systems for retrieving temporary Inferior Vena Cava (IVC) filters, other medical implants, or foreign bodies are described. These methods may employ a locking sheath or a proximal-aperture capture feature for IVC filter (or other device) retrieval. One of the methods includes: passing an elongate member having a braided funnel-shaped distal extension through a sheath, where the braided funnel-shaped distal extension includes a distal bend to form a distal aperture and a flap that defines a proximal aperture; passing an end of the medical device through the distal aperture and then through the proximal aperture to capture the medical device; and covering the medical device with the sheath.

Abstract: The embodiments described relate to retrieving temporary Inferior Vena Cava (IVC) filters and other endovascular implants or foreign bodies. Features are provided for effective actuation in closing an inner aperture of the embodiments.

Abstract: Funnel-trap type delivery and/or retrieval devices for Inferior Vena Cava (IVC) filters or other medical implants are described in which the devices comprise two layers of braid with an axially support member. The support member may be interposed between braid layers or set inside the braid layers but interposed between heatset features. Delivery and/or retrieval devices, kits in which they are included, methods of use and methods of manufacture are all contemplated herein.

Abstract: Systems, devices, and methods are provided for a catheter device for use in a medical procedure wherein the interior of the catheter device expands to accommodate longitudinal expansion of the expandable member to compress cancellous bone.

Abstract: Funnel-trap type devices or systems made of braid are described for capture and retrieval or, instead, capture and subsequent release of Inferior Vena Cava (IVC) filters or other medical devices. Delivery and/or retrieval devices, kits in which they are included, methods of use and methods of manufacture are all contemplated.

Abstract: Funnel-trap type devices are described that are made of shape-set (e.g., heatset) braid for delivery and/or retrieval of Inferior Vena Cava (IVC) filters or other medical devices. Delivery and/or retrieval devices, kits in which they are included, methods of use and methods of manufacture are all contemplated. Additional forming tooling, methods and device embodiment shapes are described herein.

Abstract: Funnel-trap type delivery and/or retrieval devices for temporary Inferior Vena Cava (IVC) filters or other medical implants or foreign bodies are described. These may employ a locking sheath or a proximal-aperture capture feature or features for IVC filter (or other device) retrieval.

Abstract: An intravascular balloon catheter includes a tubular catheter body having a balloon structure removably mounted over the catheter body. The catheter body has a guidewire lumen, and the catheter body may be left in place within a patient's vasculature while the balloon structure is withdrawn and optionally a second balloon structure introduced over the catheter body. The catheter and methods of the present invention are particularly suitable for performing angioplasty and subsequent procedures, such as stent placement, which are best performed using successive interventional balloon structures.

Abstract: The present invention provides improved devices and methods for minimizing and/or inhibiting restenosis and hyperplasia after intravascular intervention. In particular, the present invention provides luminal prostheses which allow for programmed and controlled mizoribine delivery with increased efficacy to selected locations within a patient's vasculature to inhibit restenosis. An intraluminal delivery prosthesis may comprise an expansible structure and means on or within the structure for releasing mizoribine into the body lumen to inhibit smooth muscle cell proliferation.